Zithromax vs. Augmentin

Are Zithromax and Augmentin the Same Thing?

ZithromaxZ-PAK (azithromycin) andAugmentin(amoxicillin/clavulanate) are antibiotics used to treatbacterialinfectionssinusitis,pneumonia,earinfections,bronchitis, and other types of infections caused by susceptiblebacteria.

Zithromax is also effective against several sexually transmitted infectious diseases (STDs) such as nongonococcalurethritisandcervicitis.

Zithromax and Augmentin are different types of antibiotics. Zithromax Z-PAK is amacrolideantibioticand Augmentin is a combination of apenicillin-type antibiotic and a beta-lactamase inhibitor.

What Are Possible Side Effects of Zithromax?

Commonside effectsof Zithromax include:

What Are Possible Side Effects of Augmentin?

Common side effects of Augmentin include:

Rare and severe side effects of Augmentin can include:

  • watery or bloody diarrhea;
  • pale or yellowed skin, dark coloredurine,fever, confusion or weakness;
  • easy bruising or bleeding;
  • skin rash, bruising, severe tingling, numbness, pain,muscleweakness;
  • agitation, confusion, unusual thoughts or behavior, seizures (convulsions);
  • nausea, upper stomach pain, itching, loss of appetite, clay-colored stools,jaundice(yellowing of the skin or eyes); or
  • severe skin reaction -- fever,sore throat, swelling in your face ortongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

What Is Zithromax?

Zithromax Z-PAK (azithromycin) is a semi-synthetic macrolide antibiotic used for treating:

Zithromax is also effective against several sexually transmitted infectious diseases (STDs) such as nongonococcal urethritis and cervicitis. Zithromax is available ingenericform.

What Is Augmentin?

Augmentin (amoxicillin/clavulanate) is a combination antibiotic used to treat bacterial infections including sinusitis, pneumonia, ear infections, bronchitis,urinary tractinfections, and infections of the skin.

It is not known if Augmentin is safe and effective in children.

What Drugs Interact With Zithromax?

Zithromax may interact witharsenictrioxide,cyclosporine, pimozide, tacrolimus,theophylline,warfarin, other antibiotics,antidepressants, anti-malariamedications,cholesterol-lowering medicines,ergotmedicines,heartorblood pressuremedications, heart rhythm medicines,HIVmedicines, medicine to prevent or treat nausea and vomiting, medicines to treatpsychiatricdisorders,migraine headachemedicines, narcotics, sedatives, tranquilizers, orseizuremedicines. Tell yourdoctorall medications and supplements you use.

What Drugs Interact With Augmentin?

Augmentin may interact with probenecid.

Augmentin may also interact withallopurinol,bloodthinners, or other antibiotics.

How Should Zithromax Be Taken?

A typicaloraldose of Zithromax consists of 500mgfor 1 day then 250 mg for 4 days. A typicalintravenousdose consists of 500 mg for 2 days followed by 500 mg orally daily for an additional 5-8 days.

How Should Bactrim Be Taken?

Administer the solution by intravenous infusion over a period of 60 to 90 minutes. Avoid administration by rapid infusion or bolus injection. Do NOT administerBactrimintramuscularly.

How Should Augmentin Be Taken?

For Adults:

  • The usual adult dose is one 500-mgtabletof Augmentin every 12 hours or one 250-mg tablet of Augmentin every 8 hours. For more severe infections and infections of therespiratory束,剂量应该是8月的875毫克的平板电脑mentin every 12 hours or one 500-mg tablet of Augmentin every 8 hours. Adults who have difficulty swallowing may be given the 125 mg/5 mL or 250 mg/5 mL suspension in place of the 500-mg tablet. The 200 mg/5 mL suspension or the 400 mg/5 mL suspension may be used in place of the 875-mg tablet.
  • Two 250-mg tablets of Augmentin should not be substituted for one 500-mg tablet of Augmentin. Since both the 250-mg and 500-mg tablets of Augmentin contain the same amount of clavulanic acid (125 mg, as thepotassiumsalt), two 250-mg tablets are not equivalent to one 500-mg tablet of Augmentin.
  • The 250-mg tablet of Augmentin and the 250-mg chewable tablet should not be substituted for each other, as they are not interchangeable. The 250-mg tablet of Augmentin and the 250-mg chewable tablet do not contain the same amount of clavulanic acid (as the potassium salt). The 250-mg tablet of Augmentin contains 125 mg of clavulanic acid, whereas the 250-mg chewable tablet contains 62.5 mg of clavulanic acid.

ForPediatricPatients

Based on the amoxicillin component, Augmentin should be dosed as follows:

Neonates And Infants Aged under 12 Weeks (under 3 Months)

  • The recommended dose of Augmentin is 30 mg/kg/day divided every 12 hours, based on the amoxicillin component. Experience with the 200 mg/5 mL formulation in this age group is limited, and thus, use of the 125 mg/5 mL oral suspension is recommended.

Patients Aged 12 Weeks (3 Months) And Older

  • The every 12 hourregimenis recommended as it is associated with significantly less diarrhea. However, the every 12 hour suspension (200 mg/5 mL and 400 mg/5 mL) and chewable tablets (200 mg and 400 mg) containaspartameand should not be used by phenylketonurics.
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References


DailyMed. Cefdinir Product Monograph.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=df26edb0-9bd6-449c-a187-0be0c9e2600c

Pfizer. Zithromax Product Monograph.

https://www.pfizer.com/products/product-detail/zithromax

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