Zinplava vs. Flagyl

• Are Zinplava and Flagyl the Same Thing?
• What Are Possible Side Effects of Zinplava?
• What Are Possible Side Effects of Flagyl?
• What Is Zinplava?
• What Is Flagyl?
• What Drugs Interact with Zinplava?
• What Drugs Interact with Flagyl?
• How Should Zinplava Be Taken?
• How Should Flagyl Be Taken?

Zinplava(bezlotoxumab) injection andFlagyl,Flagyl ER, andFlagyl Injection(metronidazole) are used to treatClostridium difficileinfection(CDI).

Flagyl is also used to treatbacterial vaginosis,trichomonas,amebiasis, andanaerobicbacterialinfections.

Zinplava and Flagyl belong to different drug classes. Zinplava is a humanmonoclonal antibodyand Flagyl is anantimicrobial.

Side effectsof Zinplava and Flagyl that are similar includenauseaandheadache.

Side effects of Zinplava that are different from Flagyl includefever.

Side effects of Flagyl that are different from Zinplava includeabdominalcramps,stomachupset, vomiting,diarrhea,constipation,weight loss,dizziness,dry mouth, dark-coloredurine, and a metallic味道inthemouthor changes in taste.

Zinplava may interact with other drugs.

Flagyl may interact withalcohol,foodor medicines that contain propylene glycol, busulfan,lithium, andbloodthinners.

Common side effects of Zinplava include:

• nausea,
• fever, and
• headache.

Common side effects of Flagyl include:

• nausea,
• abdominal cramps,
• stomach upset,
• vomiting,
• diarrhea,
• constipation,
• headache,
• weight loss (anorexia),
• dizziness,
• dry mouth,
• dark-colored urine, or
• a metallic taste in the mouth or changes in taste.

Uncomfortable side effects that may become serious are:

• fevers,
• painwith urination,
• mouth sores,
• 可能成为体育的刺痛或刺痛的感觉rmanent,
• braindisease, and
• seizures.

Serious but unlikely side effects of Flagyl include:

• unsteadiness,
• seizures,
• mood changes,
• numbness or tingling of the hands orfeet, and
• painful urination.

Zinplava (bezlotoxumab) injection is a humanmonoclonalantibodythat binds toClostridium difficile(C. Diff.)toxinB, indicated to reducerecurrenceofClostridium difficileinfection (CDI) in patients 18 years of age or older who are receivingantibacterialdrug treatment of CDI and are at a high risk for CDI recurrence.

Flagyl, FlagylER, and Flagyl Injection (metronidazole) are antimicrobial drugs used to treat bacterial vaginosis, trichomonas, amebiasis, and anaerobic bacterial infections.

Zinplava may interact with other drugs. Tell yourdoctorall medications and supplements you use. Tell your doctor if you arepregnantor plan to become pregnant before using Zinplava. It is unknown how it wouldaffectafetus. It is unknown if Zinplava passes intobreast milk. Consult your doctor beforebreastfeeding.

Flagyl may interact with blood thinners orseizuremedications.

Flagyl may also interact withcimetidine, lithium, or disulfiram.

The recommended dose of Zinplava is a single dose of 10mg/kg administered as anintravenousinfusion over 60 minutes.

Flagyl is supplied in 250 and 500 mg strength tablets, Flagyl ER is available in 750 mg strength tablets, and Flagyl Injection in 500 mg strength in a buffered 100 ml vial. Dosage is quite variable and dependent upon the severity of disease and other considerations made by the treatingphysician. Most of the serious side effects may occur with any of these three preparations of Flagyl. Flagyl may causeliverenzymelevels to increase; lithium andcreatininelevels should be checked to avoid lithiumtoxicityorrenalcompromise. Alcohol may increase the side effects of Flagyl. Patients on disulfiram should not take Flagyl until they have had a two week interval without taking disulfiram, especially alcoholic patients, to avoid psychotic reactions. Treatment in pregnant women (during first 3 months is not advised) or women who are breastfeeding should only be done if the benefits outweigh the potential problems. Flagyl passes intobreastmilk and may harm anursingbaby. Consult your doctor before breastfeeding. Except for use in amebiasis, studies inpediatricpatients are not available; Flagyl ER has no pediatric studies.