Vigamox vs. Polymyxin B

• Are Vigamox and Polymyxin B the Same Thing?
• What Are Possible Side Effects of Vigamox?
• What Are Possible Side Effects of Polymyxin B?
• What Is Vigamox?
• What Is Polymyxin B?
• What Drugs Interact with Vigamox?
• What Drugs Interact with Polymyxin B?
• How Should Vigamox Be Taken?
• How Should Polymyxin B Be Taken?

Vigamox(moxifloxacin hydrochlorideophthalmicsolution) andPolymyxin B(polymyxin b sulfate) are antibiotics used to treatbacterialinfections of the eyes.

Polymyxin B is also used to treat bacterial infections such asurinary tractinfections (UTIs),meningitis, andbloodinfections.

Side effectsof Vigamox and Polymyxin B that are similar includeblurred visionandeyereactions (stinging, burning, redness,itching).

Side effects of Vigamox that are different from Polymyxin B include watery eyes (tearing) and eye reactions (pain, dryness, and irritation).

Side effects of Polymyxin B that are different from Vigamox include injection site reactions (pain, redness, and swelling).

Vigamox may interact with other eye medications.

Polymyxin B may interact with other drugs that can harm the kidneys or nerves (e.g.,cisplatin, colistin, high-doseaspirin, aminoglycosides such as amikacin,gentamicin,tobramycin, nonsteroidalanti-inflammatory drugs-NSAIDssuch asibuprofenornaproxen).

Common side effects of Vigamox include:

• blurred vision,
• watery eyes (tearing), and
• eye (pain, dryness, redness, itching, burning, stinging, and irritation).

Serious side effects are not expected to occur during treatment with Vigamox. Tell yourdoctorif you have an unlikely but serious side effect of Vigamox such as swelling of the eye.

Common side effects of Polymyxin B include:

• pain,
• redness, and
• swelling at the injection site, or
• temporary eye stinging/burning/redness/itchiness or
• temporary blurred vision if used as eye drops.

Contact your doctor if you experience serious side effects of Polymyxin B including:

• flushing,
• dizziness,
• loss of coordination,
• drowsiness,
• fever,
• headache,
• numbness or tinglinginthe hands orfeet,
• back pain,
• stiffneck,
• unsteadiness,
• hives, and
• rash.

Vigamox (moxifloxacin hydrochloride ophthalmic solution) is anantibioticused to treat bacterial infections of the eyes.

Polymyxin B (polymyxin b sulfate) is an antibiotic used to treat bacterial infections such asurinarytract infections, meningitis, blood infections, and eye infections.

Do not use other eye drops or medications during treatment with Vigamox ophthalmic unless directed by your doctor. Other drugs may interact with Vigamox. Tell your doctor allprescriptionorover-the-countermedicines or supplements you use. Vigamox should be used only when prescribed duringpregnancy. It is not known if thismedicationpasses intobreast milk. Consult your doctor beforebreastfeeding.

Polymyxin B may interact with other drugs that can harm the kidneys or nerves (e.g., cisplatin, colistin, high-dose aspirin, aminoglycosides such as amikacin, gentamicin, tobramycin, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen or naproxen). Tell your doctor all medications you are taking. During pregnancy, Polymyxin B should be used only when prescribed. It is unknown if this medication passes intobreastmilk when used in the eye. It is unlikely to harm anursinginfant. Consult your doctor before breastfeeding.

The dose of Vigamox: Instill one drop in the affected eye 3 times a day for 7 days.

Polymyxin B dose is determined by a doctor, based on theconditionbeing treated. It may be injected into avein,muscle, or the spinal fluid or into the area around the eye (subconjunctival sac). It can also be prepared as eye drops.