Trintellix vs. Celexa

Trintellix(vortioxetine) andCelexa(citalopramhydrobromide) areselective serotonin reuptake inhibitor(SSRI) typeantidepressantsused to treatmajordepressive disorder (MDD).

Side effectsof Trintellix and Celexa that are similar includenausea,diarrhea,dry mouth,constipation,dizziness, and decreased sexual desire.

Side effects of Trintellix that are different from Celexa include vomiting, gas,abnormaldreams, anditching.

Side effects of Celexa that are different from Trintellix include upsetstomach,impotence, difficulty having anorgasm, drowsiness,tiredness,sleepproblems (insomnia), increasedsweatingor urination, weight changes, and cold symptoms (such asstuffy nose, sneezing,sore throat, andcough).

Both Trintellix and Celexa may interact with other antidepressants,tramadol,L-tryptophan, nonsteroidalanti-inflammatory drugs (NSAIDs),bloodthinners, anti-malariamedications,migraine headachemedicines, andseizuremedications.

Trintellix may also interact with monoamine oxidase inhibitors (MAOIs), buspirone,aspirin,bupropion, and rifampicin.

Celexa may also interact withalcohol, other drugs that make you sleepy or slow yourbreathing(such as sleeping pills, narcotics,musclerelaxers, or medicine foranxiety,depression, or seizures),lithium, St. John's wort, tacrolimus,arsenic三氧化二,vandetanib、抗生素、heartrhythm medications,HIV/AIDSmedications, medicine to prevent or treat nausea and vomiting, medicines to treatpsychiatricdisorders, and stomach acid reducers.

Do not stop using Celexa suddenly, or you could have unpleasantwithdrawal symptoms.

Common side effects of Trintellix include:

• nausea
• diarrhea
• drymouth
• constipation
• vomiting
• gas
• dizziness
• abnormal dreams
• itching, and
• decreased sexual desire

Antidepressants such as Trintellix increased the risk ofsuicidalthoughts and behaviorinchildren, adolescents, and young adults in short-term studies. Tell yourdoctorif you experience any thoughts ofsuicidewhile taking Trintellix.

Common side effects of Celexa include:

• constipation,
• nausea,
• diarrhea,
• upset stomach,
• decreased sexual desire,
• impotence,
• difficulty having an orgasm,
• dizziness,
• drowsiness,
• tiredness,
• sleep problems (insomnia),
• dry mouth,
• increased sweating or urination,
• weight changes, and cold symptoms such as stuffynose,
• sneezing,sorethroat, or
• cough.

Trintellix (vortioxetine) tablets are anantidepressantindicated for the treatment of major depressive disorder (MDD).

Celexa is aprescriptionmedicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of not treating it. You should discuss all treatment choices with your healthcare provider. Celexa is also used to treat Major Depressive Disorder (MDD).

Talk to your healthcare provider if you do not think that yourconditionis getting better with Celexa treatment.

Trintellix may interact with monoamine oxidase inhibitors (MAOIs), selectiveserotoninreuptakeinhibitors (SSRIs), serotonin去甲肾上腺素reuptake inhibitors (SNRIs), triptans, buspirone, tramadol, tryptophan products, NSAIDs, aspirin,warfarin, bupropion,fluoxetine,paroxetine, quinidine, rifampicin,carbamazepine, andphenytoin. Tell your doctor all medications and supplements you use.

Do not take Celexa if you:

• are allergic to citalopram hydrobromide orescitalopramoxalate or any of the ingredients in Celexa. See the end of thisMedicationGuide for a complete list of ingredients in Celexa.
• take amonoamine oxidase inhibitor(MAOI). Ask your healthcare provider orpharmacistif you are not sure if you take an MAOI, including theantibioticlinezolid.
• Do not take an MAOI within 2 weeks of stopping Celexa unless directed to do so by yourphysician.
• Do not start Celexa if you stopped taking an MAOI in the last 2 weeks unless directed to do so by your physician.
• People who take Celexa close in time to an MAOI may have serious or even life-threatening side effects. Get medical help right away if you have any of these symptoms:
• highfever
• uncontrolled muscle spasms
• stiff muscles
• rapid changes inheart rateorblood pressure
• confusion
• loss of consciousness (pass out)
• take theantipsychoticmedicine pimozide (Orap®) because this can cause serious heart problems.
• have a heart problem includingcongenitallong QT syndrome

Before starting Celexa, tell your healthcare provider if you are taking certain drugs such as:

• Medicines for heart problems
• Medicines that lower yourpotassiumormagnesiumlevels in your body
• Cimetidine
• Triptans used to treatmigraineheadache
• Medicines used to treat mood, anxiety, psychotic or thought disorders, including tricyclics, lithium, SSRIs, SNRIs, amphetamines, or antipsychotics
• Tramadol
• Over-the-countersupplements such as tryptophan or St. John's Wort

Before starting Celexa, tell your healthcare provider if you:

• haveliverproblems
• havekidneyproblems
• have heart problems
• have or had seizures or convulsions
• havebipolar disorderormania
• have lowsodiumlevels in your blood
• have a history of astroke
• havehigh blood pressure
• have or had bleeding problems
• arepregnantor plan to become pregnant. It is not known if Celexa will harm your unborn baby. Talk to your healthcare provider about the benefits and risks of treating depression duringpregnancy
• arebreast-feeding or plan to breastfeed. Some Celexa may pass into yourbreast milk. Talk to your healthcare provider about the best way to feed your baby while taking Celexa

Tell your healthcare provider about all the medicines that you take, including prescription and non-prescription medicines,vitamins, andherbalsupplements. Celexa and some medicines may interact with each other, may not work as well, or may cause serious side effects.

你的医疗服务提供者或药剂师可以告诉你u if it is safe to take Celexa with your other medicines. Do not start or stop any medicine while taking Celexa without talking to your healthcare provider first.

The recommended starting dose of Trintellix is 10mgadministered orally once daily without regard to meals. Dosage should then be increased to 20 mg/day, as tolerated.

Take Celexa exactly as prescribed. Your healthcare provider may need to change the dose of Celexa until it is the right dose for you.

Celexa may be taken with or withoutfood.

If you miss a dose of Celexa, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Celexa at the same time.

If you take too much Celexa, call your healthcare provider orpoison control centerright away, or get emergency treatment.