Synthroid vs. Euthyrox

• Are Synthroid and Euthyrox the Same Thing?
• What Are Possible Side Effects of Synthroid?
• What Are Possible Side Effects of Euthyrox?
• What Is Synthroid?
• What Is Euthyrox?
• What Drugs Interact with Synthroid?
• What Drugs Interact with Euthyrox?
• Synthroid应如何Taken?
• How Should Euthyrox Be Taken?

Synthroid(levothyroxine sodium) andEuthyrox(levothyroxinesodium) are synthetic compounds identical toT4(levothyroxine) produced by the humanthyroid glandused to treathypothyroidism(lowthyroid hormone).

Synthroid is also used forpituitaryTSHsuppression.

Euthyrox is also used as an adjunct tosurgery和radioiodinetherapyinthe management ofthyrotropin-dependent well-differentiatedthyroid cancer.

Side effectsof Synthroid and Euthyrox that are similar includeheadache, nervousness, irritability,sleepproblems (insomnia), heat intolerance, changes in appetite or changes in weight, and changes inmenstrualperiods.

Side effects of Synthroid that are different from Euthyrox includefever,hot flashes,sweating,nausea, and temporaryhair loss.

Side effects of Euthyrox that are different from Synthroid include irregular heartbeats,heart attack,shortness of breath,肌肉spasm, tremors, muscle weakness,diarrhea, andskinrash.

Both Synthroid and Euthyrox may interact with glucocorticoids,amiodarone,heroin/methadone,ferrous sulfate,antacids,sucralfate, clofibrate,oralcontraceptives,estrogens, 5 -fluorouracil, mitotane,tamoxifen,furosemide,heparin, hydantoins, nonsteroidalanti-inflammatory drugs (非甾体抗炎药), salicylates,carbamazepine,phenobarbital,rifampin, beta-blockers,antidepressants, antidiabetics orinsulin, anticoagulants,cardiacglycosides,ketamine, and sympathomimetics.

Synthroid may also interact withdopamine/dopamine agonists,octreotide, aminoglutethimide,iodide,lithium,methimazole,propylthiouracil(PTU),sulfonamides, tolbutamide,orlistat, cytokines, growth hormones, bronchodilators, radiographic agents,chloral hydrate,diazepam, ethionamide,lovastatin,metoclopramide, 6-mercaptopurine, nitroprusside,para-aminosalicylate sodium,perphenazine, resorcinol (excessivetopicaluse), and thiazidediuretics.

Euthyrox may also interact withcalciumcarbonate,bile acidsequestrants, ion exchange resins, proton pump inhibitors (PPIs), androgens, steroids, asparaginase, slow-releasenicotinic acid, andtyrosine-kinase inhibitors.

Common side effects of Synthroid include:

• fever,
• hot flashes,
• sensitivityto heat,
• sweating,
• headache,
• nervousness,
• 易怒,
• nausea,
• sleep problems (insomnia),
• changes in appetite or changes in weight,
• 月经的变化perdiods,
• 和temporary hair loss.

Notify yourdoctorif you experience serious side effects of Synthroid including rapid heartbeat, fluttering in yourchest, orchest pain.

Common side effects of Euthyrox include:

• irregular heartbeats,
• heartattack,
• shortness of breath,
• 肌肉spasm,
• headache,
• nervousness,
• 易怒,
• insomnia,
• tremors,
• 肌肉weakness,
• increased appetite,
• weight loss,
• diarrhea,
• heat intolerance,
• menstrual irregularities, and
• skin rash

Synthroid (levothyroxine sodium) is a synthetic compound identical to T4 (levothyroxine) produced by the humanthyroidglandused to treat hypothyroidism due to many causes (for example):

• thyroid removal,
• thyroidatrophy,
• functional T4 deficiency,
• radiation治疗甲状腺,
• 和other causes).

Synthroid is also used for pituitary TSH suppression.

Euthyrox (levothyroxine sodium) isL-thyroxine(T 4) indicated inpediatric和adult patients as replacement inprimary(thyroidal), secondary (pituitary), and tertiary (hypothalamic)congenitaloracquiredhypothyroidism; and as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroidcancer. Euthyrox is available ingenericform.

Synthroid may interact with ferrous sulfateironsupplements, sucralfate, and antacids.

Synthroid may also interact with dopamine/dopamine agonists, glucocorticoids, octreotide, aminoglutethimide, amiodarone, iodide, lithium, methimazole, propylthiouracil (PTU), sulfonamides, tolbutamide, orlistat, clofibrate, oral contraceptives, estrogens, heroin/methadone, 5-fluorouracil, mitotane, tamoxifen, furosemide, heparin, hydantoins, nonsteroidal anti-inflammatory drugs (NSAIDs), salicylates, carbamazepine, phenobarbital, rifampin, beta-adrenergic antagonists, anticoagulants, antidepressants, antidiabetics, cardiac glycosides, cytokines, growth hormones, ketamine, bronchodilators, radiographic agents, sympathomimetics, chloral hydrate, diazepam, ethionamide, lovastatin, metoclopramide, 6-mercaptopurine, nitroprusside,para-aminosalicylate sodium, perphenazine, resorcinol (excessive topical use), and thiazide diuretics.

Euthyrox may interact withcalcium carbonate, ferrous sulfate,bileacid sequestrants, ion exchange resins, proton pump inhibitors (PPIs), sucralfate, antacids, clofibrate,estrogen-containing oral contraceptives, estrogens (oral), heroin/methadone, 5-fluorouracil, mitotane, tamoxifen, androgens, steroids, asparaginase, glucocorticoids, slow-release nicotinic acid, salicylates, carbamazepine, furosemide, heparin, hydantoins, nonsteroidal anti-inflammatory drugs (NSAIDs), phenobarbital, rifampin,beta blockers, amiodarone, antidiabetic drugs or insulin, anticoagulants, digitalis glycosides, antidepressants, ketamine, sympathomimetics, and tyrosine-kinase inhibitors. Tell your doctor all medications and supplements you use.

Synthroid is prescribed in tablets thatrangefrom 25 to 300 mcg in strength and is usually taken once a day with a full glass ofwater(about 8 ounces) 30 to 60 minutes before breakfast for best adsorption into the body. Children can take the medicine if thetabletis crushed and put into about 1 to 2 teaspoons of water; do not store or delay giving this crushedpillsuspension. Doctors often may have to slowly increase the dose; patients should not increase or decrease thismedicationthemselves. Because some preparations of the drug may containiodineorlactose, patients should tell their doctors about such allergies or reactions to these components. Many drugs can inhibit Synthroid's adsorption by the body; other medications may increase or decrease its effectiveness once it is adsorbed. Providing a complete list of medications to the doctor will help with getting the correct dose established for each individual病人.Pregnant和lactating females need to discuss the dose and use of this medication with their caregivers.

Administer a dose of Euthyrox once daily, on an emptystomach, one-half to one hour before breakfast. Administer Euthyrox at least 4 hours before or after drugs that are known to interfere withabsorption.