Sinemetvs. Requip

Are Sinemet and Requip the Same Thing?

Sinemet(carbidopa-levodopa) andRequip(ropinirole) are used to treat Parkinson symptoms such asmusclestiffness, tremors, spasms, and poor musclecontrol.

Sinemetis also used to treat Parkinson symptoms caused bycarbon monoxide poisoningormanganeseintoxication.

Requip is also used to treatrestless legssyndrome(RLS).

Sinemetand Requip belong to different drug classes. Sinemet is a combination of an inhibitor of aromaticamino aciddecarboxylation and an aromatic amino acid and Requip is a non-ergolinedopamineagonist.

What Are Possible Side Effects of Sinemet?

Common side effects of Sinemet include:

Tell yourdoctorif you experience unlikely but serious side effects including:
  • greatly increasedeyeblinking/twitching,
  • fainting,
  • mental/mood changes (e.g., confusion,depression, hallucinations, thoughts ofsuicide),
  • unusual strong urges (such as increased gambling, increased sexual urges),
  • or worsening ofinvoluntarymovements/spasms.

What Are Possible Side Effects of Requip?

Common side effects of Requip include:

What is Sinemet?

Sinemet(carbidopa-levodopa) is a combination of an inhibitor of aromatic amino acid decarboxylation and an aromatic amino acid used to treat Parkinson symptoms such as

  • muscle stiffness,
  • tremors,
  • spasms,
  • and poor muscle control.
Sinemetis also used to treat Parkinson symptoms caused by carbon monoxidepoisoningor manganese intoxication.

What is Requip?

Requip (ropinirole) is a non-ergoline dopamine agonist used to treat symptoms of帕金森病, such as stiffness, tremors, muscle spasms, and poor muscle control. Requip is also used to treat restless legs syndrome (RLS). Requip is available ingenericform.

What Drugs Interact With Sinemet?

Sinemetmay interact withmetoclopramide,isoniazid,phenytoin,papaverine,antidepressants, orblood pressuremedications.

Sinemetmay also interact with other Parkinson's medications or medicines to treatpsychiatricdisorders.

What Drugs Interact With Requip?

Requip may interact with other Parkinson's medications, metoclopramide, or medicines to treat psychiatric disorders.

Requip may also interact withciprofloxacin, fluvoxamine,omeprazole,medicationused to treat nausea and vomiting, orestrogen.

Do not stop taking Requip suddenly or change your doses, or you could have unpleasantwithdrawal symptomssuch asfever, muscle stiffness, and confusion.

How Should Sinemet Be Taken?

Starting dosage is onetabletof Sinemet 25-100 (carbidopa-levodopa) three times a day. Dosage may be increased by one tablet every day or every other day, as necessary, until a dosage of eight tablets a day is reached.

How Should Requip Be Taken?

The dose of Requip depends on theconditionbeing treated and thepatient's response.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Medical Editor:John P. Cunha, DO, FACOEP

Health SolutionsFrom Our Sponsors