Sinemetvs. Mirapex

Sinemet(carbidopa-levodopa) andMirapex(pramipexole) are used to treat Parkinson symptoms such asmusclestiffness, tremors, spasms, and poor musclecontrol.

Sinemetis also used to treat Parkinson symptoms caused bycarbon monoxide poisoningormanganeseintoxication.

Mirapex is also used to treatrestless legssyndrome.

Sinemetand Mirapex belong to different drug classes. Sinemet is a combination of an inhibitor of aromaticamino aciddecarboxylation and an aromatic amino acid and Mirapex is adopamineagonist.

Side effectsof Sinemet and Mirapex that are similar includedizziness, drowsiness,blurred vision,nausea, vomiting,dry mouth, changesinappetite,constipation, trouble sleeping (insomniaor strangedreams), andheadache.

Side effects of Sinemet that are different from Mirapex includeheartburn,diarrhea, sneezing,stuffy nose,cough, other cold symptoms, musclepain, numbness or tingly feeling,skinrash, anditching.

Side effects of Mirapex that are different from Sinemet include dizziness when standing (postural hypotension),stomachpain, spinningsensation(vertigo), swelling in your hands andfeet, weight changes,memoryproblems (amnesia), forgetfulness, confusion or thinking problems, swelling in your hands or feet,impotence, loss of interest in sex, and trouble having anorgasm.

Both Sinemet and Mirapex may interact withseizuremedications,metoclopramide, and medicines to treatpsychiatricdisorders.

Sinemetmay also interact withironsupplements or a diet that is high inprotein, other Parkinson's medications,isoniazid,papaverine,blood pressuremedications, andantidepressants.

Mirapex may also interact withalcoholand other drugs that make you sleepy (narcotics, sleeping pills, muscle relaxers, or medicines foranxiety) andcimetidine.

Side effects of Sinemet include:

• dizziness,
• 睡意,
• blurred vision,
• nausea,
• vomiting,
• drymouth,
• loss of appetite,
• heartburn,
• diarrhea,
• constipation,
• sneezing,
• stuffynose,
• 咳嗽,
• other cold symptoms,
• muscle pain,
• numbness or tingly feeling,
• trouble sleeping (insomnia or strange dreams),
• skin rash,
• itching,
• and headache.

Tell yourdoctorif you experience unlikely but serious side effects including:

• greatly increasedeyeblinking/twitching,
• fainting,
• mental/mood changes (e.g., confusion,depression, hallucinations, thoughts ofsuicide),
• unusual strong urges (such as increased gambling, increased sexual urges),
• or worsening ofinvoluntarymovements/spasms.

Common side effects of Mirapex include:

• dizziness when standing (posturalhypotension)
• nausea
• dry mouth
• stomach pain
• vomiting
• constipation
• headache
• dizziness
• spinning sensation
• 睡意
• swelling in your hands and feet
• appetite or weight changes
• blurred vision
• sleepproblems (insomnia or unusual dreams)
• memory problems (amnesia)
• forgetfulness
  confusion or thinking problems
• swelling in your hands or feet
• impotence
• loss of interest in sex, or
• trouble having an orgasm

Sinemet(carbidopa-levodopa) is a combination of an inhibitor of aromatic amino acid decarboxylation and an aromatic amino acid used to treat Parkinson symptoms such as

• muscle stiffness,
• tremors,
• spasms,
• and poor muscle control.

Sinemetis also used to treat Parkinson symptoms caused by carbon monoxidepoisoningor manganese intoxication.

Mirapex (pramipexole) is a dopamine agonistmedicationused to treat symptoms of帕金森病, and restless legs syndrome.

Sinemetmay interact with metoclopramide, isoniazid,phenytoin, papaverine, antidepressants, orbloodpressure medications.

Sinemetmay also interact with other Parkinson's medications or medicines to treat psychiatric disorders.

Mirapex可能与感冒或交互allergymedicines, sedatives,narcoticpain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety, other medicines for Parkinson'sdisease, medicine to prevent or treat nausea and vomiting, or medicine to treat psychiatric disorders.

Mirapex may also interact withamantadine, cimetidine, diltiazem,ranitidine, quinidine,quinine,triamterene,verapamil,promethazine, and levodopa.

Starting dosage is onetabletof Sinemet 25-100 (carbidopa-levodopa) three times a day. Dosage may be increased by one tablet every day or every other day, as necessary, until a dosage of eight tablets a day is reached.

Mirapex is taken in tablet form three times per day.