Histamine:Asubstancethat plays amajorroleinmany allergic reactions,dilatingbloodvessels and making thevesselwalls abnormally permeable.Histamine是身体的自然的一部分过敏再保险吗sponse to substances such as pollens.Antihistamineswork by preventing the release of histamine from certain cells (mast cells) thereby blocking theallergic reaction.