Rituxan vs. Tysabri

Are Rituxan and Tysabri the Same Thing?

Rituxan(rituximab) andTysabri(natalizumab) aremonoclonalantibodies used to treatmultiple sclerosis(MS).

Rituxan is used off-label to treat MS.

Rituxan is also usedincombination with othercancermedicines to treat non-Hodgkin'slymphoma, and in combination with another drug calledmethotrexateto treat symptoms of adultrheumatoid arthritis.

Tysabri is also used to treat moderate to severeCrohn's disease在成人。其他Cr后Tysabri通常是给定的ohn'sdiseasemedications have been tried without successful treatment of thiscondition.

What Are Possible Side Effects of Rituxan?

Commonside effectsof Rituxan include:

Tell yourdoctorif you experience serious side effects of Rituxan including:

  • increased thirst or urination,
  • swelling of the hands orfeet, or
  • tingling of the hands or feet.

What Are Possible Side Effects of Tysabri?

Common side effects of Tysabri include:

Tell your doctor if you have side effects while Tysabri is being given or shortly after your treatment is finished (infusion reaction) including:

  • chills,
  • fever,
  • flushing,
  • nausea,
  • dizziness, and
  • chest pain.

What is Rituxan?

Rituxan (rituximab) is a cancermedicationused in combination with other cancer medicines to treat non-Hodgkin's lymphoma. Rituxan is also used in combination with another drug called methotrexate to treat symptoms of adult rheumatoidarthritis.

What is Tysabri?

Tysabri (natalizumab) is amonoclonal antibodyused in to treat relapsing forms of multiplesclerosis. Tysabri is also used to treat moderate to severe Crohn's disease in adults. Tysabri is usually given after other Crohn's disease medications have been tried without successful treatment of this condition.

What Drugs Interact With Rituxan?

Rituxan may interact withcisplatin,adalimumab, auranofin,azathioprine,cyclosporine道,英夫利昔单抗,leflunomide,minocycline,sulfasalazine,blood pressuremedications, or medication to treatmalaria.

What Drugs Interact With Tysabri?

Tysabri may interact with other medicines, especially those that mayaffecttheimmune systemsuch as:interferon, cyclosporine,sirolimus, tacrolimus, basiliximab, efalizumab,muromonab-CD3,mycophenolatemofetil, azathioprine, leflunomide, etanercept, orchemotherapyorradiationtreatments.

How Should Rituxan Be Taken?

Rituxan is administered under aphysician's supervision. The dose of Rituxan varies depending on the disorder being treated and the number of infusions (doses) needed.

How Should Tysabri Be Taken?

The recommended dose of Tysabri for multiple sclerosis or Crohn's disease is 300mgintravenousinfusion over one hour every four weeks.

Disclaimer

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References


Genentech. Rituxan Product Monograph.

http://www.rituxan.com/

Biogen. Tysabri Product Monograph.

https://www.tysabri.com

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