Protonix vs. Prilosec

Protonix(pantoprazolesodium) andPrilosec(omeprazole) are proton pump inhibitors (PPIs) used to treatgastroesophageal refluxdisease(GERD) and a history of erosiveesophagitis.

Prilosec is also used to treat ulcers and frequentheartburn.

Protonix is available byprescriptionwhile Prilosec is availableover-the-counter(OTC) and as ageneric.

Side effectsof Protonix include:

• injection site reactions (redness,pain, swelling),
• headache,
• nausea,
• vomiting,
• abdominalorstomachpain,
• diarrhea,
• gas,
• dizziness,
• jointpain,
• weight changes,
• drowsiness,
• tiredfeeling, or
• sleepproblems (insomnia).

Common side effects of Prilosec include:

• headache,
• nausea,
• vomiting,
• diarrhea,
• stomach pain,
• gas,
• constipation,
• fever, or
• cold symptoms (stuffy nose, sneezing, andsore throat).

What is Prilosec?

Prilosec (omeprazole) is a proton pump inhibitor (PPI) used for the treatment of conditions such as ulcers,gastroesophagealrefluxdisease (GERD), andZollinger-Ellison syndrome, which are all caused by stomach acid.

Protonix may interact with atazanavir,bloodthinners,digoxin,diuretics(waterpills),ketoconazole, ormethotrexate.

Protonix may also interact with nelfinavir,ampicillin, oriron.

Prilosec may interact with digoxin, diuretics (water pills), blood thinners,antifungal药物往下h as ketoconazole, antibiotics such as ampicillin, iron, or methotrexate, andHIVorAIDS药物往下h as atazanavir and nelfinavir.

Prilosec may also interact with bosentan,cilostazol,clopidogrel,cyclosporine,diazepam, disulfiram, St. John's wort, tacrolimus, orseizuremedications.

The recommended adult dose of Protonix is 40mgonce daily.

• ProtonixOralSuspension should be taken 30 minutes before a meal
• Protonix Oral Suspension should only be taken with applesauce or apple juice 30 minutes before a meal.
• Protonix口服悬挂不应inor with water or other liquids, or with other foods.
• Protonix Oral Suspension should not be chewed or crushed.
• Protonix Oral Suspension packet should not be divided to make a smaller dose.

The recommended adult oral dose of Prilosec ranges from 20 mg to 60 mg once daily, depending on theconditionbeing treated. For maximal efficacy, Prilosec tablets should be taken before meals, swallowed whole and should not be crushed, chewed or opened.