Prometrium vs. Provera

Are Provera and Prometrium the Same Thing?

Prometrium(progesterone) andProvera(medroxyprogesterone) are forms of thefemalehormoneprogesterone prescribed to preventendometrial hyperplasiainnon-hysterectomizedpostmenopausalwomen receiving conjugatedestrogenstablets and also forsecondary amenorrhea.

Provera is also used to treatabnormalbleeding from theuterusdue to hormonal imbalance and not due tofibroids, orcancer; for contraception; and for treating endometrial orrenal cancer.

What Are Possible Side Effects of Prometrium?

Commonside effectsof Prometrium include:

What Are Possible Side Effects of Provera?

Common side effects of Provera include:

  • breasttenderness or discharge,
  • hives,
  • itching,
  • skinrash,
  • increased acne,
  • 头发的生长,
  • loss of scalp hair,
  • spotting or break-through bleeding,
  • changes inmenstrualperiods,
  • vaginal itching or discharge,
  • changes in appetite,
  • increased or decreased weight,
  • nausea,
  • stomachpain,
  • bloating,
  • fever,
  • sleepproblems (insomnia), and
  • jaundice(yellowing of the skin or eyes), or
  • skin colorchanges.

Provera may increase risk ofheartattacks,stroke,breast cancer,blood clots, andpulmonaryemboliin postmenopausal women.

What Is Prometrium?

Prometrium (progesterone) is aprogestin, a female hormone, prescribed for the prevention of endometrialhyperplasiain nonhysterectomized postmenopausal women receiving conjugated estrogens tablets and also for secondaryamenorrhea. Prometrium is available as ageneric drug.

What is Provera?

醋酸甲羟孕酮(甲羟孕酮)是一种形式的有限元法ale hormone progesterone used to treat secondary amenorrhea; abnormal bleeding from the uterus due to hormonal imbalance and not due to fibroids, or cancer; and to prevent endometrial hyperplasia in postmenopausal women who have not undergone ahysterectomyand are receiving conjugated estrogens. Provera is used for contraception and for treating endometrial orrenalcancer.

What Drugs Interact With Prometrium?

Drug interactions include inhibitors of cytochrome P450 3A4 (for example,ketoconazole),colchicine,dabigatranetexilate (Pradaxa), silodosin (Rapaflo) and aminoglutethimide (Cytadren). Do not use Prometrium without yourdoctor's consent if you arepregnant. Tell your doctor if you become pregnant during treatment. Talk to your doctor about using birthcontrolwhile you are using Prometrium.

What Drugs Interact With Provera?

Provera may interact with other drugs. Tell your doctor all medications and supplements you use. Avoid smoking while taking Provera due to a greatly increased risk ofbloodclots. Provera passes intobreast milkand may harm anursingbaby. Consult your doctor beforebreastfeeding.

How Should Prometrium Be Taken?

Prometrium dose depends on theconditionthat is being treated.

How Should Provera Be Taken?

The dose of Provera varies depending on theindication. Provera inhibitsfertilityat high doses.

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References


FDA. Prometrium Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019781s013lbl.pdf

Pfizer. Provera Product Information.

http://labeling.pfizer.com/ShowLabeling.aspx?id=605

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