Prometrium vs. Crinone

• Are Crinone and Prometrium the Same Thing?
• What Are Possible Side Effects of Prometrium?
• What Are Possible Side Effects of Crinone?
• What Is Prometrium?
• What Is Crinone?
• What Drugs Interact with Prometrium?
• What Drugs Interact with Crinone?
• How Should Prometrium Be Taken?
• How Should Crinone Be Taken?

Prometrium(progesterone) andCrinone(progesterone) are forms of thefemalehormoneprogesterone used to treatsecondary amenorrhea.

Prometrium is also prescribed to preventendometrial hyperplasiainnon-hysterectomizedpostmenopausalwomen receiving conjugatedestrogenstablets.

Crinone is also used to treatinfertilewomen with progesterone deficiency.

Prometrium and Crinone are taken in different forms. Prometrium is acapsuletaken orally and Crinone is a bioadhesive vaginal gel.

Commonside effectsof Prometrium include:

• dizziness,
• spinningsensation,
• abdominal pain(cramping),
• headache,
• breast painor tenderness,
• musculoskeletalpain,
• jointpain,
• viral infection,
• diarrhea,
• nausea,
• bloating,
• fatigue,
• hot flashes,
• cough,
• acne,
• increased hair growth,
• changes in weight,
• vaginalitching/dryness/discharge,
• blurred vision,
• drowsiness,
• mood swings, and
• 红外ritability.

Common side effects of Crinone include:

• bloating,
• stomachpain,
• dizziness,
• drowsiness,
• tiredfeeling,
• headache,
• nausea,
• vomiting,
• stomach cramps,
• diarrhea,
• constipation,
• pain in your vaginal orrectalarea,
• pain during intercourse,
• loss of interest in sex,
• breastswelling or tenderness,
• joint ormusclepain,
• increased night-time urination,
• vaginal discharge,
• vaginal burning, and
• vaginal itching.

Tell yourdoctorif you have serious side effects of Crinone including:

• sudden headache, numbness or weakness (especially on one side of the body):
• shortness of breath, or problems with vision, speech, orbalance;
• chest painor heavy feeling, pain spreading to thearmorshoulder;
• pain or swelling in one or both legs;
• stomach pain, loss of appetite, darkurine, clay-colored stools,jaundice(yellowing of theskinor eyes);
• swelling in your hands, ankles, orfeet;
• fever,chills, body aches,flusymptoms;
• abreast lump; or
• symptoms ofdepression(sleepproblems, weakness, mood changes).

Prometrium (progesterone) is aprogestin, a female hormone, prescribed for the prevention of endometrialhyperplasiain nonhysterectomized postmenopausal women receiving conjugated estrogens tablets and also for secondaryamenorrhea. Prometrium is available as ageneric drug.

Crinone (progesterone) gel is a bioadhesive vaginal gel contained in single-use, one-piece polyethylene vaginal applicators. Crinone is indicated as treatment for infertile women with progesterone deficiency and women with secondary amenorrhea. Crinone is available as agenericdrug.

Drug interactions include inhibitors of cytochrome P450 3A4 (for example,ketoconazole),colchicine,dabigatranetexilate (Pradaxa), silodosin (Rapaflo) and aminoglutethimide (Cytadren). Do not use Prometrium without your doctor's consent if you arepregnant. Tell your doctor if you become pregnant during treatment. Talk to your doctor about using birthcontrolwhile you are using Prometrium.

Crinone may interact with other drugs.

Prometrium dose depends on theconditionthat is being treated.

Crinone is available in strengths of 4% gel (45mg) and 8% gel (45 mg) in single use vaginal applicators. Crinone 4% is indicated for the treatment of secondary amenorrhea is dosed every other day for 6 total doses. Crinone 8% is indicated for use in women who have failed to respond to treatment with Crinone 4% but is dosed forinfertilitytreatment at twice daily for 10 – 12 weeks.