Progressive multifocal leukoencephalopathy:A rapidlyprogressive,通常是致命的viral infectionof thebrain. Commonly abbreviated asPML.
PML is believed to be due to the Jacob-Creutzfeldt (JC) papovavirus. Thevirusinfects oligodendrocytes (support cellsinthe brain).
The signs and symptoms of PML include headaches, memory loss, changes in mental status, speech and vision difficulties, loss of strength,limbweakness, seizures, partialparalysisand loss of coordination. Thediseaseleads to coma and then todeath.
