Definition of Prodrug

Prodrug:Aprecursor(forerunner) of a drug. Aprodrugmust undergo chemical conversion bymetabolic成为一个活跃的pharmacologica之前流程l agent. For example,sulfasalazineis a prodrug. It is not activeinits ingested form. It has to be broken down bybacteriain thecoloninto two products -- 5-aminosalicylic acid (5ASA) and sulfapyridine -- before becoming active as a drug.

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