Procardia vs. Cozaar

Are Procardia and Cozaar the Same Thing?

Procardia(nifedipine) andCozaar(losartan) are used to treathypertension(high blood pressure).

Procardia is also used to treat心绞痛(chest pain).

Procardia and Cozaar belong to different drug classes. Procardia is acalcium channel blockerand Cozaar (losartan) is anoralangiotensin receptor blocker(ARB).

Side effectsof Procardia and Cozaar that are similar includedizziness,legpainor cramps,headache,tiredfeeling,diarrhea,stomachpain, orsleepproblems (insomnia).

Side effects of Procardia that are different from Cozaar include weakness, swelling ankles/feet,jointpain, drowsiness,nausea,constipation,rashoritching, urinating more than usual, or flushing (warmth/redness/tingly feeling under yourskin).

Side effects of Cozaar that are different from Procardia includemusclecramps,back pain, and cold orflusymptoms such asstuffy nose, sneezing,sore throat,fever, andcough.

Procardia may interact with otherheartmedications to treat the same or anothercondition,grapefruitand grapefruit juice,cimetidine,erythromycin, itraconazole orketoconazole,carbamazepine,苯妥英,rifampin, or rifabutin.

Cozaar may interact withalcohol,potassiumsupplements orsaltsubstitutes,diuretics(waterpills), otherblood pressuremedications,lithium, or nonsteroidalanti-inflammatory drugs (NSAIDs).

What Are Possible Side Effects of Procardia?

Common side effects of Procardia include:

  • dizziness,
  • weakness,
  • swelling ankles/feet,
  • joint pain,
  • leg cramps,
  • headache,
  • drowsiness,
  • tired feeling,
  • nausea,
  • diarrhea,
  • constipation,
  • stomach pain,
  • 睡眠问题(失眠),
  • rash or itching,
  • urinating more than usual, or
  • flushing (warmth/redness/tingly feeling under your skin).

Tell yourdoctorif you experience unlikely but serious side effects of Procardia including:

  • fast/irregular/pounding heartbeat, or
  • fainting.

What Are Possible Side Effects of Cozaar?

Common side effects of Cozaar include:

  • diarrhea
  • stomach pain
  • muscle cramps
  • leg or back pain
  • dizziness
  • headache
  • 睡眠问题(失眠)
  • tiredness, and
  • cold or flu symptoms such as stuffynose, sneezing,sorethroat, fever, and cough

Tell your doctor if you experience serious side effects of Cozaar including pain or burning when you urinate; pale skin,lightheadedness,shortness of breath, rapidheart rate, trouble concentrating;wheezing,chestpain; drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting; swelling, weight gain, urinating less than usual or not at all; or high potassium (slow heart rate, weakpulse, muscle weakness, tingly feeling).

What Is Procardia?

Procardia (nifedipine) is acalciumchannel blocker used to treat hypertension (highblood压力)nd to treat angina (chest pain).

What Is Cozaar?

Cozaar (losartan) is an oralangiotensinreceptorblocker (ARB) prescribed for the treatment of hypertension.

What Drugs Interact With Procardia?

Procardia may interact with other heart medications to treat the same or another condition, cimetidine, erythromycin, itraconazole or ketoconazole, carbamazepine, phenytoin, rifampin, or rifabutin. Tell your doctor all medications you use. Duringpregnancy, Procardia should be used only when prescribed. Thismedicationpasses intobreast milk. Consult your doctor beforebreastfeeding.

What Drugs Interact With Cozaar?

Cozaar may interact with diuretics (water pills), other blood pressure medications, lithium, celecoxib, oraspirinor other nonsteroidal anti-inflammatory drugs (NSAIDs).

How Should Procardia Be Taken?

The usual starting dose of Procardia is one 10mgcapsule, 3 times/day. The usualeffective doserangeis 10–20 mg three times daily.

How Should Cozaar Be Taken?

Dosing preparations of Cozaar are 25, 50, and 100 mg tablets. Drug interactions with Cozaar may occur with inhibitors of cytochrome P450, potassium- sparing diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). Cozaar should not be used during pregnancy, and it is not known whether it is excretedinbreastmilk.

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References

FDA. Procardia XL Product Information.
http://labeling.pfizer.com/showlabeling.aspx?id=542
FDA. Cozaar Product Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020386s058lbl.pdf

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