Definition of PML

PML:Stands for progressivemultifocalleukoencephalopathy, a rapidly progressive, often fatalviral infectionof the brain. Commonly abbreviated asPML.

PML is believed to be due to the Jacob-Creutzfeldt (JC) papovavirus. The virus infects oligodendrocytes (support cells in the brain).

PML的体征和症状包括头痛,memory loss, changes in mental status, speech and vision difficulties, loss of strength, limb weakness, seizures, partialparalysisand loss of coordination. The disease leads to coma and then to death.

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