Plavix vs. Pradaxa

• Are Pradaxa and Plavix the Same Thing?
• What Are Possible Side Effects of Plavix?
• What Are Possible Side Effects of Pradaxa?
• What is Plavix?
• What is Pradaxa?
• What Drugs Interact with Plavix?
• What Drugs Interact with Pradaxa?
• How Should Plavix Be Taken?
• How Should Pradaxa Be Taken?

Plavix(clopidogrelbisulfate) andPradaxa(dabigatran) are anticoagulants (bloodthinners) that inhibit aspects of blood clotting and are used to treat patients withacutecoronarysyndrome,heart attack(myocardial infarction),peripheral vascular disease, and ischemic strokes.

Commonside effectsof Plavix include:

• easy bleeding and bruising;
• pain, redness, warmth, irritation, orskinchanges where the medicine was injected;
• itchingof yourfeet; or
• bluish-colored skin.

Thrombocytopenia, pradaxa-induced thrombocytopenia (HIT) and pradaxa-induced thrombocytopenia andthrombosis(HITT) are serious side effects of pradaxa.

Common side effects of Pradaxa include:

• bruising andminorbleeding (such as nosebleeds and bleeding fromcuts),
• nausea,
• abdominalorstomachpain,
• stomach upset,
• indigestion,
• heartburn,
• diarrhea,
• skinrash, or
• itching.

Tell yourdoctorif you have serious side effects of Pradaxa including:

• severe heartburn,
• nausea, or
• vomiting.

Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibitsplatelet aggregationand thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardialinfarction(MI),peripheralvasculardiseaseand somestroke(ischemic type) patients. Plavix is availableingenericform.

Pradaxa (dabigatran) is an抗凝剂that works by blocking the clottingproteinthrombin. Pradaxa is used to preventblood clotsfrom forming because of a certain irregularheartrhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke.

Plavix may interact with other blood thinners,aspirin, or nonsteroidalanti-inflammatory drugs (NSAIDs).

Plavix may also interact witharmodafinil,modafinil,fluoxetine, fluvoxamine,gemfibrozil,isoniazid,cancermedications, stomach acid reducers, antifungals,HIVmedications, orseizuremedications.

Pradaxa may interact with other medicines to treat or prevent blood clots, aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), antifungals, or HIV/AIDSmedications.

Pradaxa可能艾尔so interact with antibiotics, St. John's wort, heart orblood pressuremedications, or medicines used to preventorgantransplantrejection.

Plavix is supplied as 75 and 300mgtablets. For acute coronary syndrome with a non-ST elevation MI, the initial recommended dose is 300 mg, followed by a 75 mg dose per day; for ST elevation MIs, the initial and continuing dose is 75 mg per day. The recommended dose is 75 mg per day forpatientwith a history of MI, stroke, or peripheral vascular disease. Many doctors may choose to add an aspirin per day along with the Plavix dose in both non-ST elevation and ST elevation MIs as well as to stroke and peripheral vascular disease patients.

The usual recommended dose of Pradaxa is 150 mg taken orally, twice daily Pradaxa is administered incapsuleform.