Plavix vs. Brilinta

• Are Brilinta and Plavix the Same Thing?
• What Are Possible Side Effects of Plavix?
• What Are Possible Side Effects of Brilinta?
• What is Plavix?
• What is Brilinta?
• What Drugs Interact with Plavix?
• What Drugs Interact with Brilinta?
• How Should Plavix Be Taken?
• How Should Brilinta Be Taken?

Plavix(clopidogrelbisulfate) andBrilinta(ticagrelor) are anticoagulants (bloodthinners) that inhibit aspects of blood clotting and are used to treat patients withacutecoronarysyndrome,heart attack(myocardial infarction),peripheral vascular disease, and ischemic strokes.

Commonside effectsof Plavix include:

• increased bleeding,
• nosebleeds,
• headaches,
• itching, and
• bruising.

Tell yourdoctorif you have serious side effects of Plavix including:

• bleeding that will not stop;
• bloody or tarry stools, bloodin你的urine;
• coughing up bloodorvomitthat looks like coffee grounds;
• chest painor heavy feeling,painspreading to thearmorshoulder,nausea,sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• suddenheadache, confusion, problems with vision, speech, orbalance;
• paleskin, weakness,fever, orjaundice(yellowing of the skin or eyes);
• unusual bleeding (nose,mouth,vagina, orrectum), or
• purple or red pinpoint spots under your skin.

Common side effects of Brilinta include:

• bruising
• bleeding more easily
• nosebleeds
• headache
• dizziness
• cough
• nausea
• diarrhea
• irregular heartbeat
• high blood pressure
• back pain
• 低血总统sure
• fatigue, and
• chestpain.

Tell your doctor if you experience serious side effects of Brilinta including severe bleeding or uncontrollable bleeding,shortness of breath, colored urine (pink, red, or brown), red or black stools (looks like tar), coughing or vomiting that produces blood orblood clots, or vomit that looks like coffee grounds.

Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibitsplatelet aggregationand thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardialinfarction(MI),peripheralvasculardiseaseand somestroke(ischemic type) patients. Plavix is available ingenericform.

Brilinta (ticagrelor) is ablood-thinnerused to reducecardiovasculardeathandheartattack in patients withacute coronary syndromes(ACS). Brilinta works by preventing the formation of new blood clots, thus maintaining blood flow in the body to help reduce the risk of another cardiovascularevent.

Plavix may interact with other blood thinners, antifungals,HIV/AIDSmedications, orseizuremedications.

Plavix may also interact withaspirin, nonsteroidalanti-inflammatory drugs (NSAIDs),armodafinil,modafinil,fluoxetine, fluvoxamine,gemfibrozil,isoniazid,cancermedications, orstomachacid reducers.

Brilinta may interact with other blood thinners, antifungals, HIV/AIDS medications, orseizure medications.

Brilinta may also interact withdexamethasone,digoxin, nefazodone, antibiotics,cholesterol-lowering medications, or heart orblood pressuremedications.

Plavix is supplied as 75 and 300mgtablets. For acute coronary syndrome with a non-ST elevation MI, the initial recommended dose is 300 mg, followed by a 75 mg dose per day; for ST elevation MIs, the initial and continuing dose is 75 mg per day. The recommended dose is 75 mg per day forpatientwith a history of MI, stroke, or peripheral vascular disease. Many doctors may choose to add an aspirin per day along with the Plavix dose in both non-ST elevation and ST elevation MIs as well as to stroke and peripheral vascular disease patients.

Brilinta should be started with two 90 mg tablets as a loading dose, continuing treatment with 90 mg twice daily. After the initial loading dose of aspirin (usually 325 mg), use Brilinta with a daily maintenance dose of aspirin of 75-100 mg. Patients who have received a loading dose of clopidogrel may be started on Brilinta. A patient who misses a dose of Brilinta should take one 90 mgtablet(their next dose) at its scheduled time.