Nubeqa vs. Erleada

Are Nubeqa and Erleada the Same Thing?

Nubeqa(darolutamide) andErleada(apalutamide tablets) are androgenreceptorinhibitors indicated for the treatment of patients with non-metastatic castration-resistantprostatecancer.

Side effects of Nubeqa and Erleada that are similar includefatigue,pain/swellinginextremities, andrash.

Side effects of Erleada that are different from Nubeqa include highblood pressure(hypertension), rash,diarrhea,nausea,weight loss,jointpain, falls, hot flushes, decreased appetite, and fractures.

Nubeqa may interact with rifampicin, itraconazole, midazolam, androsuvastatin.

Erleada可能与药物相互作用that are sensitive substrates of CYP3A4, CYP2C19, CYP2C9, UGT, P-gp, BCRP, or OATP1B1.

What Are Possible Side Effects of Nubeqa?

Common side effects of Nubeqa include:

  • fatigue,
  • pain in extremities, and
  • rash

What Are Possible Side Effects of Erleada?

Common side effects of Erleada include:

  • fatigue,
  • high blood pressure(hypertension),
  • rash,
  • diarrhea,
  • nausea,
  • weight loss,
  • joint pain,
  • falls,
  • 潮热,
  • decreased appetite,
  • fractures, and
  • swelling of extremities

What Is Nubeqa?

Nubeqa (darolutamide) is an androgen receptor inhibitor indicated for the treatment of patients with non-metastatic castration-resistant prostate cancer.

What Is Erleada?

Erleada (apalutamide tablets) is anandrogenreceptor inhibitor indicated for the treatment of patients with non-metastaticcastration-resistantprostate cancer.

What Drugs Interact With Nubeqa?

Nubeqa may interact with rifampicin, itraconazole, midazolam, and rosuvastatin. Tell yourdoctorall medications and supplements you use.

What Drugs Interact With Erleada?

Erleada can be taken with or withoutfood. Erleada may interact with medications that are sensitive substrates of CYP3A4, CYP2C19, CYP2C9, UGT, P-gp, BCRP, or OATP1B1. Tell your doctor all medications and supplements you use.

How Should Nubeqa be Taken?

The dose of Nubeqa is 600mg, (two 300 mg tablets) administered orally twice daily with food. Patients should also receive agonadotropin-releasinghormone(GnRH)analogconcurrently or should have hadbilateralorchiectomy.

How Should Erleada be Taken?

The dose of Erleada is 240 mg (four 60 mg tablets) administered orally once daily. Swallow tablets whole.

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References
Bayer Pharmaceuticals. Nubeqa Product Information

https://www.nubeqahcp.com/

Janssen. Erleada Product Information.

https://www.erleadahcp.com/

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