Macrobid vs. Bactrim

Are Macrobid and Bactrim the Same Thing?

Macrobid(nitrofurantoin monohydrate/macrocrystals) andBactrim(sulfamethoxazole andtrimethoprim) are antibiotics used to treaturinary tractinfections.

Macrobid is also used to treatbladderinfections.

Bactrim is also used to treat ear infections (acute otitis media),bronchitis,Shigellosis,Pneumocystis pneumonia,traveler's diarrhea,甲氧西林-resistant Staphylococcus aureus(MRSA), and other bacterial infections.

Bactrim is prescribed to treat Candida fungal infections of the mouth,vagina,esophagus,lungs, urinary tract, abdomen, and other organs. Bactrim is also used to treat fungalmeningitisand may be prescribed to ward off fungal infections in patients being treated withchemotherapyorradiationbefore abone marrowtransplant.

What Are Possible Side Effects of Macrobid?

Common side effects of Macrobid include:

  • nausea,
  • vomiting,
  • upset stomach,
  • diarrhea,
  • rust-colored or brownish urine,
  • vaginal itching ordischarge,
  • headaches, and
  • gas.

Tell your doctor if you experience serious side effects of Macrobid including:

  • bloody or watery diarrhea,
  • sudden chest pain,
  • shortness of breath,
  • 咳嗽,
  • fever or chills,
  • numbness or tingling in the hands or feet, or
  • easy bruising.

What Are Possible Side Effects of Bactrim?

Common side effects of Bactrim include:

  • loss of appetite,
  • nausea,
  • vomiting,
  • painful orswollen tongue,
  • dizziness,
  • spinning sensation,
  • ringing in your ears,
  • tiredness, or
  • sleep problems (insomnia).

Tell your doctor if you experience serious side effects of Bactrim including:

What is Macrobid?

Macrobid (nitrofurantoin monohydrate/macrocrystals) is anantibacterialdrug used to treat urinary tract and bladder infections caused byEscherichia coliorStaphyloccocus saprophyticusstrains of bacteria that are sensitive to this drug. Macrobid is available as ageneric. Macrobid should not be used forpyelonephritis(kidney infections) or other deep tissue infections such as perinephric abscesses.

What is Bactrim?

Bactrim (sulfamethoxazole and trimethoprim) DS is a combination of two antibiotics used to treat urinary tract infections, acuteotitis media, bronchitis, Shigellosis,Pneumocystispneumonia, traveler's diarrhea,甲氧西林-resistantStaphylococcusaureus (MRSA), and other bacterial infections susceptible to thisantibiotic. Bactrim is available as ageneric drug.

What Drugs Interact With Macrobid?

Macrobid may also interact with magnesium salicylate or choline magnesium salicylate.

What Drugs Interact With Bactrim?

Bactrim may interact with blood thinners,cyclosporine,methotrexate, oraldiabetesmedications, andseizuremedications. Bactrim may also interact withantidepressants,digoxin,diuretics(water pills), indomethacin,leucovorin, calcium folinate, and heart or blood pressure medications.

How Should Macrobid Be Taken?

Macrobid is available in 100 mg tablets for use in children under 12 years old and adults. Macrobid may interact with magnesium salicylate, choline magnesium salicylate, and probenecid or othergoutmedications.

How Should Bactrim Be Taken?

Bactrim is available in tablets in two strengths; 400 mg sulfamethoxazole and 80 mg trimethoprim and the "DS" form which means double strength, 800 mg sulfamethoxazole and 160 mg trimethoprim. Patients should follow their doctor's instructions and take all of the Bactrim prescribed. Patients allergic to sulfa compounds should not take Bactrim. Bactrim may interact with many drugs; the patient and prescribing doctor should be aware of any potential interactions. Bactrim should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus; the same situation exists for women who are breastfeeding and their neonates.

Disclaimer

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The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

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If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

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References
SOURCE:

DailyMed. Macrobid Prescribing Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1971e893-5fdb-41e3-a1e9-5e52deed03d1

DailyMed. Bactrim Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1ba409b6-8dcd-41d2-aa9e-81b77f87ea14

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