Linzess vs. Viberzi

Are Linzess and Viberzi the Same Thing?

Linzess(linaclotide) andViberzi(eluxadoline) are used to treat different forms ofirritable bowel syndrome. Linzess is used to treat irritablebowelsyndromewithconstipation(IBS-C) and

Viberzi用于治疗肠易激综合症withdiarrhea(IBS-D).

Linzess is also used to treatchronicidiopathicconstipation (CIC)inadults.

Linzess is a guanylate cyclase-Cagonistand Viberzi is a mu-opioidreceptoragonist.

What Are Possible Side Effects of Linzess?

Commonside effectsof Linzess include:

What Are Possible Side Effects of Viberzi?

Common side effects of Viberzi include:

What Is Linzess?

Linzess (linaclotide) is a guanylate cyclase-C agonist used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) in adults.

What Is Viberzi?

Viberzi (eluxadoline) is a mu-opioid receptor agonist used in adults to treat irritable bowel syndrome with diarrhea (IBS-D).

What Drugs Interact With Linzess?

Linzess may interact with other drugs.

What Drugs Interact With Viberzi?

Viberzi may interact with other irritable bowel medications,narcoticpain medicines, orheartrhythm medications.

Viberzi may also interact withcyclosporine,gemfibrozil, antiretrovirals,rifampin, eltrombopag,ciprofloxacin,fluconazole,clarithromycin,paroxetine,bupropion, anticholinergics, opioids,rosuvastatin, dihydroergotamine, ergotamine, pimozide,sirolimus, or tacrolimus.

How Should Linzess Be Taken?

The recommended dose of Linzess for those with irritable bowel syndrome (IBS) is 290 mcg taken once a day on an empty stomach, at least 30 minutes before the first meal of the day. The same applies for those with chronic idiopathic constipation only the dosage is 145 mcg.Pediatricpatients under the age of 17 should not take Linzess.

How Should Viberzi Be Taken?

The recommended dosage of Viberzi in adults is 100mgtwice daily, taken withfood.

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References

Allergan/Ironwood. Linzess Product Information.
https://www.linzess.com
Allergan. Viberzi Product Information.
https://www.viberzi.com

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