Libraxvs. Valium

• Are Valium and Librax the Same Thing?
• What Are Possible Side Effects of Librax?
• What Are Possible Side Effects of Valium?
• What is Librax?
• What is Valium?
• What Drugs Interact with Librax?
• What Drugs Interact with Valium?
• How Should Librax Be Taken?
• How Should Valium Be Taken?

Librax(chlordiazepoxide and clidinium bromide) andValium(diazepam) both containbenzodiazepinesand are used to treat different conditions.

Libraxalso contains ananticholinergic/spasmolytic and used to treatstomachulcers,irritable bowel syndrome, and intestinal infections.

Valium is used to treatanxiety, seizures,musclespasms, and symptoms ofalcoholwithdrawal.

The brand name Librax is no longer availableinthe U.S.Genericversions may be available.

Side effectsof Librax and Valium that are similar includedizziness, drowsiness,tiredness, weakness,blurred vision,dry mouth,nausea,constipation, orskinrash.

Side effects of Librax that are different from Valium include dry eyes, vomiting,abdominalbloating, swelling, and irregularmenstrualperiods.

副作用的安定re different from Librax include spinningsensation,fatigue、失去balance,memoryproblems, restlessness, irritability, drooling, slurred speech, double vision,itching, or loss of interest in sex.

Both Librax and Valium may interact with alcohol, narcotics, orantidepressants.

Libraxmay also interact withbarbiturates,bloodthinners, MAO inhibitors, or medicines to treatpsychiatricdisorders.

Valium may also interact withgrapefruitand grapefruit juice, other drugs that make you sleepy or slow yourbreathing(sleeping pills,prescriptioncoughmedicines, muscle relaxers, or medicines for anxiety or seizures),cimetidine,酮康唑, oromeprazole.

Do not stop using Librax or Valium suddenly after long-term use, or you could have unpleasantwithdrawal symptoms.

• dizziness,
• drowsiness,
• tiredness,
• weakness,
• blurred vision,
• dry eyes,
• drymouth,
• nausea,
• vomiting,
• constipation,
• abdominal bloating,
• swelling,
• skin rash, and
• irregular menstrual periods.

Tell yourdoctorif you have unlikely but serious side effects of Librax (chlordiazepoxide and clidinium bromide) including:

• decreasedsweating,
• dry/hot/flushed skin,
• fast or irregular heartbeat,
• loss of coordination,
• slurred speech,
• fainting,
• uncontrollable or unusual muscle movements,
• mental/mood changes (such as confusion, agitation, unusual excitement,depression, or strange thoughts),
• difficulty urinating,
• decreased sexual ability, or
• slow or shallow breathing.

Common side effects of Valium include:

• drowsiness,
• tiredfeeling,
• dizziness,
• spinning sensation,
• fatigue,
• constipation,
• ataxia(loss of balance),
• memory problems,
• restlessness,
• 易怒,
• muscle weakness,
• nausea,
• drooling,
• dry mouth,
• slurred speech,
• blurred or double vision,
• skin rash,
• itching, or
• loss of interest in sex.

Librax(chlordiazepoxide and clidinium bromide) is a combination of a benzodiazepine and an anticholinergic/spasmolytic used to treat stomach ulcers, irritablebowelsyndrome, and intestinal infections.

Valium is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety ortensionassociated with thestressof everyday life usually does not require treatment with an anxiolytic.

Inacutealcohol withdrawal, Valium may be useful in thesymptomaticreliefc of acute agitation,tremor, impending or acutedelirium tremensand hallucinosis.

Libraxmay interact with other medicines that make you sleepy (such as cold orallergymedicine, sedatives,narcoticpainmedicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), or MAO inhibitors.

Libraxmay also interact with alcohol, barbiturates, or medicines to treat psychiatric disorders.

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If Valium is to be combined with other centrally acting agents, careful consideration should be given to thepharmacologyof the agents employed particularly with compounds that may potentiate or be potentiated by the action of Valium, such as phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics,sedativeantihistamines, narcotics, barbiturates, MAO inhibitors and other antidepressants.

Alcohol

Concomitant use with alcohol is not recommended due to enhancement of the sedative effect.

Antacids

Diazepam peak concentrations are 30% lower whenantacidsare administered concurrently. However, there is no effect on the extent ofabsorption. The lower peak concentrations appear due to a slower rate of absorption, with the time required to achieve peak concentrations on average 20 - 25 minutes greater in the presence of antacids. However, this difference was not statistically significant.

Librax(lorazepam) is administered orally. For optimal results, dose, frequency of administration, and duration oftherapyshould be individualized according topatientresponse. To facilitate this, 0.5mg, 1 mg, and 2 mg tablets are available.

The usualrangeis 2 to 6 mg/day given in divided doses, the largest dose being taken before bedtime, but the daily dosage may vary from 1 to 10 mg/day.

For anxiety, most patients require an initial dose of 2 to 3 mg/day given two or three times a day.

For insomnia due to anxiety or transient situational stress, a single daily dose of 2 to 4 mg may be given, usually at bedtime.

For elderly or debilitated patients, an initial dosage of 1 to 2 mg/day in divided doses is recommended, to be adjusted as needed and tolerated.

The dosage of Librax (lorazepam) should be increased gradually when needed to help avoid adverse effects. When higher dosage is indicated, the evening dose should be increased before the daytime doses.

The dosage of chlordiazepoxide and clidinium varies with thediagnosisand response of the individual patient. The usual maintenance dose is 1 or 2 capsules (5 mg chlordiazepoxide hydrochloride and 2.5 mg clidinium bromide), 3 or 4 times a day administered before meals and at bedtime.