Libraxvs. Donnatal

• Are Donnatal and Librax the Same Thing?
• What Are Possible Side Effects of Librax?
• What Are Possible Side Effects of Donnatal?
• What is Librax?
• What is Donnatal?
• What Drugs Interact with Librax?
• What Drugs Interact with Donnatal?
• How Should Librax Be Taken?
• How Should Donnatal Be Taken?

Librax(chlordiazepoxide and clidinium bromide) andDonnatal(belladonnaalkaloids,phenobarbital) are used to treat ulcers andirritable bowel syndrome．

Libraxis also used to treat intestinal infections.

Donnatal is also used to treatacuteinflammationof thestomachand intestines (gastroenteritis).

Libraxand Donnatal are different drug combinations. Librax is a combination of a benzodiazepine and ananticholinergic/spasmolytic and Donnatal is a combination of an anticholinergic/antispasmodicdrug and a barbituratesedative．

The brand name Librax is no longer availableinthe U.S.Genericversions may be available.

Side effectsof Librax and Donnatal that are similar includedizziness, drowsiness, weakness,blurred vision, dry eyes,dry mouth,nausea, vomiting,constipation, orabdominalbloating.

Side effects of Librax that are different from Donnatal includetiredness, swelling,skinrash, and irregularmenstrualperiods.

Side effects of Donnatal that are different from Librax include increasedsensitivityto light, decreasedtastesensation, decreasedsweatingor urination,headache,sleepproblems (insomnia), restlessness, excitability,impotence, loss of interest in sex, or trouble having anorgasm．

Both Librax and Donnatal may interact withalcohol,bloodthinners, or MAO inhibitors.

Libraxmay also interact withbarbiturates, medicines to treatpsychiatricdisorders, narcotics, orantidepressants．

Donnatal may also interact withketoconazole,atropine,benztropine, dimenhydrinate, methscopolamine,scopolamine,glycopyrrolate, mepenzolate, bronchodilators,bladderorurinarymedications, irritablebowelmedications, or hormonal birthcontrol．

Do not stop using Librax suddenly after long-term use, or you could have unpleasantwithdrawal symptoms．

• dizziness,
• drowsiness,
• tiredness,
• weakness,
• blurred vision,
• dry eyes,
• drymouth,
• nausea,
• 呕吐物ing,
• constipation,
• abdominal bloating,
• swelling,
• skin rash, and
• irregular menstrual periods.

Tell yourdoctorif you have unlikely but serious side effects of Librax (chlordiazepoxide and clidinium bromide) including:

• decreased sweating,
• dry/hot/flushed skin,
• fast or irregular heartbeat,
• loss of coordination,
• slurred speech,
• fainting,
• uncontrollable or unusualmusclemovements,
• mental/mood changes (such as confusion, agitation, unusual excitement,抑郁症, or strange thoughts),
• difficulty urinating,
• decreased sexual ability, or
• slow or shallowbreathing．

Common side effects of Donnatal include:

• dizziness,
• drowsiness,
• weakness,
• blurred vision,
• dry eyes,
• dry mouth,
• nausea,
• 呕吐物ing,
• constipation,
• abdominal bloating,
• increased sensitivity to light,
• decreased taste sensation,
• decreased sweating or urination,
• headache,
• sleep problems (insomnia),
• restlessness,
• excitability,
• impotence,
• loss of interest in sex, or
• trouble having an orgasm.

Tell your doctor if you have unlikely but serious side effects of Donnatal including:

• dry/hot/flushed skin,
• fast or irregular heartbeat,
• loss of coordination,
• slurred speech,
• fainting,
• mental/mood changes (such as confusion, agitation, unusual excitement, depression, rare thoughts ofsuicide),
• difficulty urinating, or
• slow or shallow breathing.

Librax(chlordiazepoxide and clidinium bromide) is a combination of a benzodiazepine and an anticholinergic/spasmolytic used to treat stomach ulcers, irritable bowelsyndrome, and intestinal infections.

Donnatal (belladonna alkaloids, phenobarbital) is a combination of an anticholinergic/antispasmodic drug and a barbiturate sedative used to treatabdominal pain, bloating and cramps in patients with irritable bowel syndrome. Donnatal is also used to treat acute inflammation of the stomach and intestines (gastroenteritis) to reducepainanddiarrhea, and in patients withduodenal ulcer．在常规形态Donnatal是可用的。

Libraxmay interact with other medicines that make you sleepy (such as cold orallergymedicine, sedatives,narcoticpain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, oranxiety), or MAO inhibitors.

Libraxmay also interact with alcohol, barbiturates, or medicines to treat psychiatric disorders.

Products that may interact with Donnatal include blood thinners, ketoconazole, MAO inhibitors, bronchodilators, bladder or urinary medications or irritable bowel medications. Hormonalbirth controlproducts (pills, patch, ring) may not be effective if taken with Donnatal. Discuss all medications you are taking with your doctor. Donnatal is not recommended for use duringpregnancy．It may harm afetus．Consult your doctor. Thismedicationpasses intobreast milkand may have undesirable effects on anursing婴儿．Consult your doctor beforebreastfeeding．Donnatal may cause withdrawal symptoms (anxiety, muscletwitching, shakiness, dizziness, worsening weakness, nausea, vomiting) if you suddenly stop using it. Withdrawal from phenobarbital can be severe and include seizures ordeath．

Librax(lorazepam) is administered orally. For optimal results, dose, frequency of administration, and duration oftherapyshould be individualized according topatient响应。为了促进这一点,0.5mg, 1 mg, and 2 mg tablets are available.

The usualrange是2到6毫克/天/剂量,the largest dose being taken before bedtime, but the daily dosage may vary from 1 to 10 mg/day.

For anxiety, most patients require an initial dose of 2 to 3 mg/day given two or three times a day.

For insomnia due to anxiety or transient situational stress, a single daily dose of 2 to 4 mg may be given, usually at bedtime.

For elderly or debilitated patients, an initial dosage of 1 to 2 mg/day in divided doses is recommended, to be adjusted as needed and tolerated.

The dosage of Librax (lorazepam) should be increased gradually when needed to help avoid adverse effects. When higher dosage is indicated, the evening dose should be increased before the daytime doses.

The dosage of Donnatal is adjusted to individual patients forsymptomaticcontrol with minimum adverse reactions. The usual dose is onetabletevery 8 or 12 hours as prescribed.