Levsin vs. Librax

Are Levsin and Librax the Same Thing?

Levsin(hyoscyamine) andLibrax(chlordiazepoxide and clidinium bromide) are used to treat differentstomachand intestinal disorders, includingpeptic ulcerandirritable bowel syndrome

Levsin is also used tocontrolmusclespasmsinthebladder, kidneys, or digestive tract, and to reduce stomach acid. Levsin is sometimes used to reduce tremors and rigid muscles in people with symptoms ofParkinson's disease, and is also used as a drying agent to control excessive salivation,runny nose, or excessivesweating

Libraxis also used to treat intestinal infections.

The brand name Librax is no longer available in the U.S.Genericversions may be available.

Levsin is one of the principalanticholinergic/antispasmodiccomponents ofbelladonnaalkaloids and Librax is a combination of a benzodiazepine and an anticholinergic/spasmolytic.

Side effectsof Levsin and Librax that are similar includedizziness, drowsiness,blurred vision,dry mouth,constipation,nausea, vomiting, or bloating.

Side effects of Levsin that are different from Librax include nervousness,headache, trouble sleeping (insomnia),heartburn, changes intaste, problems with urination,impotence, loss of interest in sex, trouble having anorgasm, flushing,dry skin, and decreased sweating.

Side effects of Librax that are different from Levsin includetiredness, weakness, dry eyes, swelling,skinrash, and irregularmenstrualperiods.

Both Levsin and Librax may interact withalcohol, MAO inhibitors, orantidepressants

Levsin may also interact withamantadine,haloperidol, or phenothiazines.

Libraxmay also interact withbarbiturates,bloodthinners, medicines to treatpsychiatricdisorders, or narcotics.

Withdrawal symptomsmay occur if Librax is stopped abruptly.

What Are Possible Side Effects of Levsin?

Common side effects of Levsin include:

  • dizziness,
  • drowsiness,
  • nervousness,
  • blurred vision,
  • drymouth,
  • vision problems,
  • headache,
  • trouble sleeping (insomnia),
  • constipation,
  • nausea,
  • vomiting,
  • bloating,
  • heartburn,
  • changes in taste,
  • problems with urination,
  • impotence,
  • loss of interest in sex,
  • trouble having an orgasm,
  • flushing,
  • dry skin, and
  • decreased sweating.

Tell yourdoctorif you experience unlikely but serious side effects of Levsin including:

  • mental/mood changes (e.g., confusion, unusual excitement),
  • fast/irregular heartbeat,
  • loss of coordination, or
  • slurred speech.

What Are Possible Side Effects of Librax?

Common side effects of Librax include:

  • dizziness,
  • drowsiness,
  • tiredness,
  • weakness,
  • blurred vision,
  • dry eyes,
  • dry mouth,
  • nausea,
  • vomiting,
  • constipation,
  • abdominalbloating,
  • swelling,
  • skin rash, and
  • irregular menstrual periods.

Tell your doctor if you have unlikely but serious side effects of Librax (chlordiazepoxide and clidinium bromide) including:

  • decreased sweating,
  • dry/hot/flushed skin,
  • fast or irregular heartbeat,
  • loss of coordination,
  • slurred speech,
  • fainting,
  • uncontrollable or unusual muscle movements,
  • mental/mood changes (such as confusion, agitation, unusual excitement,depression, or strange thoughts),
  • difficulty urinating,
  • decreased sexual ability, or
  • slow or shallowbreathing

What Is Levsin?

Levsin (hyoscyamine) is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids used to treat different stomach and intestinal disorders, including pepticulcerand irritablebowelsyndrome。Levsin也是用来控制肌肉痉挛the bladder, kidneys, or digestive tract, and to reduce stomach acid. Levsin is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson'sdisease, and is also used as a drying agent to control excessive salivation, runnynose, or excessive sweating. Levsin is available in generic form.

What Is Librax?

Librax(chlordiazepoxide and clidinium bromide) is a combination of a benzodiazepine and an anticholinergic/spasmolytic used to treat stomach ulcers, irritable bowel syndrome, and intestinal infections.

What Drugs Interact With Levsin?

Levsin may interact with amantadine, haloperidol, MAO inhibitors, phenothiazines, or antidepressants. Tell your doctor all medications you use. Levsin should be used only when prescribed duringpregnancy。This drug passes intobreast milk。Consult your doctor beforebreastfeeding

What Drugs Interact With Librax?

Libraxmay interact with other medicines that make you sleepy (such as cold orallergymedicine, sedatives,narcoticpainmedicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, oranxiety), or MAO inhibitors.

Libraxmay also interact with alcohol, barbiturates, or medicines to treat psychiatric disorders.

How Should Levsin Be Taken?

Dosage of Levsin for adults and children 12 years of age and older: 1 to 2 tablets every four hours or as needed. Do not exceed 12 tablets in 24 hours.Pediatricpatients 2 to under 12 years of age: ½ to 1tabletevery four hours or as needed. Do not exceed 6 tablets in 24 hours.

How Should Librax Be Taken?

Librax(lorazepam) is administered orally. For optimal results, dose, frequency of administration, and duration oftherapyshould be individualized according topatientresponse. To facilitate this, 0.5mg, 1 mg, and 2 mg tablets are available.

The usualrange是2到6毫克/天/剂量,the largest dose being taken before bedtime, but the daily dosage may vary from 1 to 10 mg/day.

For anxiety, most patients require an initial dose of 2 to 3 mg/day given two or three times a day.

For insomnia due to anxiety or transient situationalstress, a single daily dose of 2 to 4 mg may be given, usually at bedtime.

For elderly or debilitated patients, an initial dosage of 1 to 2 mg/day in divided doses is recommended, to be adjusted as needed and tolerated.

The dosage of Librax (lorazepam) should be increased gradually when needed to help avoid adverse effects. When higher dosage is indicated, the evening dose should be increased before the daytime doses.

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References

DailyMed. Levsin Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0918c44e-54f6-47b9-b927-4f1b0b394152&audience=consumer
FDA. Librax Prescribing Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/012750s065lbl.pdf

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