Levsin vs. Donnatal

Are Levsin and Donnatal the Same Thing?

Levsin(hyoscyamine) andDonnatal(belladonnaalkaloids,phenobarbital) are used to treat differentstomachand intestinal disorders, includingpeptic ulcerandirritable bowel syndrome

Levsin is also used tocontrolmusclespasmsinthebladder, kidneys, or digestive tract, and to reduce stomach acid. Levsin is sometimes used to reduce tremors and rigid muscles in people with symptoms of帕金森病, and is also used as a drying agent to control excessive salivation,流鼻涕, or excessivesweating

Donnatal is also used to treatacuteinflammationof the stomach and intestines (gastroenteritis) to reducepainanddiarrhea, and in patients withduodenal ulcer

Both Levsin and Donnatal contain belladonna alkaloids, and Donnatal also contains a barbituratesedative

Side effectsof Levsin and Donnatal that are similar includedizziness, drowsiness,blurred vision,dry mouth,headache, trouble sleeping (insomnia),constipation,nausea, vomiting, bloating, changes in味道, problems with urination,impotence, loss of interest in sex, trouble having anorgasm, or decreased sweating.

Side effects of Levsin that are different from Donnatal include nervousness, vision problems,heartburn, flushing, ordry skin

Side effects of Donnatal that are different from Levsin include weakness, dry eyes, increasedsensitivityto light, restlessness, or excitability.

Both Levsin and Donnatal may interact withalcoholor MAO inhibitors.

Levsin may also interact withamantadine,haloperidol, phenothiazines, orantidepressants

Donnatal may also interact withbloodthinners,ketoconazole, bronchodilators, bladder orurinarymedications, irritablebowelmedications, or hormonalbirth control

Withdrawal symptomsmay occur if you suddenly stop taking Donnatal.

What Are Possible Side Effects of Levsin?

Common side effects of Levsin include:

  • dizziness,
  • drowsiness,
  • nervousness,
  • blurred vision,
  • drymouth,
  • vision problems,
  • headache,
  • trouble sleeping (insomnia),
  • constipation,
  • nausea,
  • vomiting,
  • bloating,
  • heartburn,
  • changes in taste,
  • problems with urination,
  • impotence,
  • loss of interest in sex,
  • trouble having an orgasm,
  • flushing,
  • dryskin, and
  • decreased sweating.

Tell yourdoctorif you experience unlikely but serious side effects of Levsin including:

  • mental/mood changes (e.g., confusion, unusual excitement),
  • fast/irregular heartbeat,
  • loss of coordination, or
  • slurred speech.

What Are Possible Side Effects of Donnatal?

Common side effects of Donnatal include:

  • dizziness,
  • drowsiness,
  • weakness,
  • blurred vision,
  • dry eyes,
  • dry mouth,
  • nausea,
  • vomiting,
  • constipation,
  • abdominalbloating,
  • increased sensitivity to light,
  • decreased tastesensation,
  • decreased sweating or urination,
  • headache,
  • sleepproblems (insomnia),
  • restlessness,
  • excitability,
  • impotence,
  • loss of interest in sex, or
  • trouble having an orgasm.

Tell your doctor if you have unlikely but serious side effects of Donnatal including:

  • dry/hot/flushed skin,
  • fast or irregular heartbeat,
  • loss of coordination,
  • slurred speech,
  • fainting,
  • mental/mood changes (such as confusion, agitation, unusual excitement,depression, rare thoughts ofsuicide),
  • difficulty urinating, or
  • slow or shallowbreathing

What Is Levsin?

Levsin (hyoscyamine) is one of the principalanticholinergic/antispasmodiccomponents of belladonna alkaloids used to treat different stomach and intestinal disorders, including pepticulcerand irritable bowelsyndrome。Levsin也是用来控制肌肉痉挛the bladder, kidneys, or digestive tract, and to reduce stomach acid. Levsin is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson'sdisease, and is also used as a drying agent to control excessive salivation, runnynose, or excessive sweating. Levsin is available ingenericform.

What Is Donnatal?

Donnatal (belladonna alkaloids, phenobarbital) is a combination of an anticholinergic/antispasmodic drug and a barbiturate sedative used to treatabdominal pain, bloating and cramps in patients with irritable bowel syndrome. Donnatal is also used to treat acute inflammation of the stomach and intestines (gastroenteritis) to reduce pain and diarrhea, and in patients withduodenalulcer. Donnatal is available in generic form.

What Drugs Interact With Levsin?

Levsin may interact with amantadine, haloperidol, MAO inhibitors, phenothiazines, or antidepressants. Tell your doctor all medications you use. Levsin should be used only when prescribed duringpregnancy。This drug passes intobreast milk。Consult your doctor beforebreastfeeding

What Drugs Interact With Donnatal?

Products that may interact with Donnatal include blood thinners, ketoconazole, MAO inhibitors, bronchodilators, bladder or urinary medications or irritable bowel medications. Hormonal birth control products (pills, patch, ring) may not be effective if taken with Donnatal. Discuss all medications you are taking with your doctor. Donnatal is not recommended for use during pregnancy. It may harm afetus。Consult your doctor. Thismedicationpasses intobreastmilk and may have undesirable effects on anursinginfant。Consult your doctor before breastfeeding. Donnatal may cause withdrawal symptoms (anxiety, muscletwitching, shakiness, dizziness, worsening weakness, nausea, vomiting) if you suddenly stop using it. Withdrawal from phenobarbital can be severe and include seizures ordeath

How Should Levsin Be Taken?

Dosage of Levsin for adults and children 12 years of age and older: 1 to 2 tablets every four hours or as needed. Do not exceed 12 tablets in 24 hours.Pediatricpatients 2 to under 12 years of age: ½ to 1tabletevery four hours or as needed. Do not exceed 6 tablets in 24 hours.

How Should Donnatal Be Taken?

The dosage of Donnatal is adjusted to individual patients forsymptomaticcontrol with minimum adverse reactions. The usual dose is one tablet every 8 or 12 hours as prescribed.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

DailyMed. Levsin Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0918c44e-54f6-47b9-b927-4f1b0b394152&audience=consumer
RedHill Biopharma. Donnatal Prescribing Information.
https://www.redhillbio.com/donnatal

Health SolutionsFrom Our Sponsors