Januvia vs. Glucotrol

• Are Januvia and Glucotrol the Same Thing?
• What Are Possible Side Effects of Januvia?
• What Are Possible Side Effects of Glucotrol?
• What Is Januvia?
• What Is Glucotrol?
• What Drugs Interact with Januvia?
• What Drugs Interact with Glucotrol?
• How Should Januvia Be Taken?
• How Should Glucotrol Be Taken?

Januvia(sitagliptin) andGlucotrol(glipizide) areoraldiabetesmedicines for people withtype 2 diabetes(non-insulin-dependent) diabetes.

Januvia is sometimes usedincombination with other diabetes medications, but is not for treatingtype 1 diabetes.

Side effectsof Januvia and Glucotrol that are similar includeheadache,nausea,diarrhea, orconstipation.

Side effects of Januvia that are different from Glucotrol include runny orstuffy nose,sore throat,back pain,jointormusclepain, orstomachpain.

Side effects of Glucotrol that are different from Januvia include vomiting, upset stomach, loss of appetite, weight gain,skinchanges (skinrash,hives, redness,itching, and blisters), gas, drowsiness, anddizziness.

Januvia may interact with otheranti-diabetic medications,digoxin, probenecid, nonsteroidal anti-inflammatory drugs (NSAIDs),aspirinor other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers.

Glucotrol may interact withalcoholand other drugs.

Common side effects of Januvia include:

• runny or stuffynose,
• sorethroat,
• headache,
• back pain,
• joint or muscle pain,
• nausea,
• stomach pain,
• diarrhea, or
• constipation.

Although Januvia by itself usually does not cause低血糖(hypoglycemia), lowblood sugar可能发生如果Januvia规定with other anti-diabetic medications. Symptoms of lowbloodsugar include suddensweating, shaking, fast heartbeat, hunger,blurred vision, dizziness, or tingling hands/feet.

Common side effects of Glucotrol include:

• diarrhea
• constipation
• nausea
• vomiting
• upset stomach
• loss of appetite
• headache
• weight gain,
• skin changes (skin rash, hives, redness, itching, and blisters)
• gas
• drowsiness, and
• dizziness

Tell yourdoctorif you experience serious side effects of Glucotrol including easy bruising or bleeding (nosebleeds, bleeding gums),tiredness,shortness of breath, upper stomach pain, itching, darkurine, clay-colored stools,jaundice(yellowing of the skin or eyes); pale skin,fever, confusion; or throbbing headache, severe nausea and vomiting, fast or pounding heartbeats, sweating or thirst, or feeling like you might pass out.

Januvia (sitagliptin) is an oral diabetes medicine for people with type 2 diabetes (non-insulin-dependent) diabetes. Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Many people using Januvia do not have serious side effects.

Glucotrol (glipizide) isblood glucoselowering drug of thesulfonylureaclass used to help maintainglucosecontrolin type 2 diabetics, in conjunction with an appropriate diet and exercise program. Glucotrol is available as agenericnamed glipizide.

Januvia may interact with digoxin, probenecid, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers. Tell your doctor allprescriptionandover-the-countermedications you use. DuringpregnancyJanuvia should be used only when prescribed. Pregnancy may cause or worsen diabetes. Your doctor may change your diabetes treatment during pregnancy. It is unknown if this drug passes intobreast milk. Consult your doctor beforebreastfeeding.

Many drugs may interact with Glucotrol; patients should carefully check glucose levels and inform their doctors about what medications they are taking. There are no adequate and well controlled studies of Glucotrol inpregnantwomen. Glucotrol (glipizide) should be used during pregnancy or breastfeeding women only if the potential benefit justifies the potential risk to thefetusandinfant.

The recommended dose of Januvia is 100mgonce daily.

Glucotrol is available in 5 and 10 mg strength tablets. The usual starting dose is 5 mg about 30 min before breakfast.