What Are Tetracyclines and How Do They Work?
Tetracyclines are a class of antibiotics that work against a variety of infections. Theiranti-microbial actions have been reported even beyond their well-known effects ongram-positive andgram-negativebacterialinfections caused by Chlamydiae, Mycoplasmas, Rickettsiae, and even some protozoal parasites. Although their action across many bacterial infections is very effective, they are not effective againstviralinfections.
Tetracyclineinterferes with the ability of thebacteriato produce certainvitalproteinsrequired for bacterial growth. They target the ribosomal machinery within the bacteria that assembles proteins fromamino acids. Due to this mode of action, tetracyclines inhibit bacterial growth rather than killing them. Tetracyclinesprohibitproteinsynthesisinboth human and bacterial cells. However, bacteria transport tetracyclines to theircell, whereas human cells do not. Human cells, therefore, are spared from the adverse effects of tetracycline.
How Are Tetracyclines Used?
Tetracyclines are mainly used to treat infections of:
Tetracyclines are also prescribed for:
- Pneumonia
- Plague
- Tularemia
- Food poisoning
- Anthrax
- Cholera
- Rickettsial infections
- Trachoma
- Psittacosis
- Brucellosis
What Are Side Effects of Tetracyclines?
Some of the side effects of tetracyclines include:
- Nausea
- Vomiting
- Diarrhea
- Itchingof therectumorvagina
- Swollen tongue
- Black or hairytongue
- Soreor irritatedthroat
- Loss of appetite
If the above side effects don’t seem to resolve, you should inform yourphysician.
Some of the severe side effects that require immediate medical注意include:
- Musclepain
- Naildiscoloration
- Skinrash
- Hives
- Chest pain
- Difficulty inbreathingor swallowing
- Jointstiffness or swelling
- Unusual bleeding or bruising
- 水或血便
- Fever,sore throat,chills, or other signs of infections
- Swelling of face, throat, tongue, orlips
The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor. Also, irrational use of antibiotics can increase your risk of getting an infection later that resists antibiotic treatment.
What Are Names of Tetracycline Drugs?
Names of Tetracycline drugs include:
- Achromycin V
- Acticlate
- Actisite
- Adoxa
- Atridox
- Avidoxy
- Declomycin
- Demeclocycline
- Doryx
- Doryx MPC
- Doxy
- Doxycin
- Doxycycline
- Dynacin
- Eravacycline
- Minocin
- Minocin Kit
- Minocycline
- Minolira
- Monodox
- Nuzyra
- Ocudox
- Omadacycline
- Oracea
- Periostat
- Sarecycline
- Seysara
- Solodyn
- Sumycin
- Tetracycline
- Vibramycin
- Xerava
- Ximino
From![WebMD Logo](https://images.medicinenet.com/images/promo/logo_webmd.gif)
Infectious Disease Resources
Featured Centers
Health SolutionsFrom Our Sponsors
https://reference.medscape.com/drugs/tetracyclines
WebMD. Tetracycline HCL.
https://www.webmd.com/drugs/2/drug-5919/tetracycline-oral/details
Medline Plus. Tetracycline.
https://medlineplus.gov/druginfo/meds/a682098.html
NCBI. Tetracycline Antibiotics: Mode of Action, Applications, Molecular Biology, and Epidemiology of Bacterial Resistance.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC99026/