How do opioid agonists work?
Opioidagonists are medications used for the short-term management of moderate-to-severeacute pain. Opioid agonists relievepainby stimulating opioid receptors. Opioid receptors areproteinmolecules on神经细胞(神经细胞on) membranesinthecentralandperipheralnervous systems.
Opioid receptors mediate the body’s response to most hormones and some of their functions include modulating pain,stressresponse,respiration, mood, and emotion. Opioid agonists stimulate mu-opioid receptors, one of the five types of opioid receptors in the human body.
Opioid agonists work by binding to mu-opioid receptors and inhibiting the release of chemicals (neurotransmitters) that transmit pain signals between the neurons.
How are opioid agonists used?
What are side effects of opioid agonists?
Side effects of opioid agonists may include the following:
- Nausea
- Vomiting
- Dizziness
- Hypoxia(inadequateoxygenin tissues)
- Somnolence(drowsiness)
- Pruritus(itching)
- Constipation
- Sedation
- Back pain
- Decreased oxygen saturation in theblood
Information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with yourdoctororpharmacistto make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking yourmedicationand never change your dose or frequency without consulting your doctor.