Fosamax vs. Reclast

• Are Fosamax and Reclast the Same Thing?
• What Are Possible Side Effects of Fosamax?
• What Are Possible Side Effects of Reclast?
• What is Fosamax?
• What is Reclast?
• What Drugs Interact with Fosamax?
• What Drugs Interact with Reclast?
• How Should Fosamax Be Taken?
• How Should Reclast Be Taken?

Fosamax(alendronatesodium) andReclast(zoledronic acid) are bisphosphonates used to treat and preventosteoporosis, and to treat Paget's disease.

Reclastis also used to treat high blood levels of calcium caused by cancer such ashypercalcemiaofmalignancy,multiple myeloma(a type ofbone marrowcancer), or cancer that has spread from elsewhere in the body to the bone.

Common side effects of Fosamax include:

• gas,
• 便秘,
• heartburn,
• diarrhea,
• bloating,
• nausea,
• vomiting,
• stomach pain,
• joint pain or swelling,
• swelling in your hands or feet,
• dizziness,
• headache,
• eye pain,
• back pain, or
• weakness.

Serious side effects of Fosamax include:

• 严重的疼痛(关节、骨、muscle, jaw, back or heartburn),
• chest pain,
• difficulty swallowing,
• 血腥的凳子,
• eye pain,
• skin blisters, and
• swelling of the face, tongue, or throat.

Common side effects of Reclast include:

The most common side effects of Reclast ishypoglycemia, or low blood sugar. Symptoms include:

• nausea,
• tiredness,
• flu-like symptoms (e.g., fever, chills, muscle/joint aches),
• 咳嗽,
• dizziness,
• headache,
• vision problems,
• diarrhea,
• 便秘,
• joint or muscle pain, or
• injection site reactions (pain, redness, swelling).

Fosamax (alendronate sodium) is abisphosphonatethat is a specific inhibitor of osteoclast-mediated boneresorptionused to both treat and prevent osteoporosis, and to treat Paget's disease.

Reclastis a prescription medicine used to:

• Treat or prevent osteoporosis in women aftermenopause. Reclast helps reduce the chance of having a hip or spinalfracture(break).
• Increase bone mass in men with osteoporosis.
• Treat or prevent osteoporosis in either men or women who will be takingcorticosteroidmedicines for at least one year.
• Treat certain men and women who have Paget's disease of the bone.

It is not known how long Reclast works for the treatment and prevention of osteoporosis. You should see your doctor regularly to determine if Reclast is still right for you.

Reclastis not for use in children.

Fosamax may interact withaspirinor otherNSAIDs(non-steroidal anti-inflammatory drugs).

Reclastmay interact with different drugs. Reclast may interact withdiuretics(water pills), antibiotics, other medicines that can harm your kidneys, cancer medicines, or nonsteroidal anti-inflammatory drugs (NSAIDs).

Fosamax is available in a tablet or oral liquid form. Each bottle of the oral solution contains 91.35 mg of alendronate monosodium salt trihydrate, which is the molar equivalent to 70 mg of the drug. The recommended initial dosage is one 70 mg molar equivalent tablet or oral liquid bottle once weekly or one 10 mg molar equivalent tablet per day. Fosamax must be taken at least one-half hour before the first food, beverage, or medication of the day with plain water only to avoid any reduction ingastrointestinaladsorption.

• Your doctor will tell you how often you will receive Reclast.
• Reclastis given by infusion into your vein (intravenously). Your infusion should last at least 15 minutes.
• Before you receive Reclast, drink at least 2 glasses of fluid (such as water) within a few hours as directed by your doctor.
• You may eat before your treatment with Reclast.
• If you miss a dose of Reclast, call your doctor or healthcare provider to schedule your next dose.