Effexor XR vs. Celexa

Are Celexa and Effexor XR the Same Thing?

Effexor XR(venlafaxinehydrochloride extended-release) andCelexa(citalopramhydrobromide) areantidepressantsused to treat depression.

EffexorXR is also used to treat panic and social disorders.

Effexor XR and Celexa are different types of antidepressants. Effexor XR is a selectiveserotoninand去甲肾上腺素reuptakeinhibitor (SSNRI) and Celexa is aselective serotonin reuptake inhibitor(SSRI)。

What Are Possible Side Effects of Effexor XR?

Common side effects of Effexor XR include:

  • nausea,
  • constipation,
  • insomnia,
  • dizziness,
  • asthenia,
  • drowsiness,
  • dry mouth,
  • nervousness,
  • strangedreams,
  • blurred vision,
  • changes in appetite or weight,
  • decreased sex drive,
  • impotence,
  • difficulty having anorgasm, and
  • increased sweating.

Tell your doctor if you have unlikely but serious side effects of Effexor XR including:

  • easy bruising or bleeding,
  • decreased interest in sex,
  • changes in sexual ability,
  • muscle cramps or weakness, or
  • shaking (tremors).

Serious side effects of Effexor XR include clinical worsening of symptoms and suicide risk, especially in younger patients. Tell your doctor if you experience worsening depression or thoughts of suicide while taking Effexor XR.

What Are Possible Side Effects of Celexa?

Common side effects of Celexa include:

  • constipation,
  • nausea,
  • diarrhea,
  • upset stomach,
  • decreased sexual desire,
  • impotence,
  • difficulty having an orgasm,
  • dizziness,
  • drowsiness,
  • tiredness,
  • sleep problems (insomnia),
  • dry mouth,
  • increased sweating or urination,
  • weight changes, and cold symptoms such asstuffy nose,
  • sneezing,sore throat, or
  • cough.

What Is Effexor XR?

惠士XR(盐酸文拉法辛extended-release) is anantidepressantused to treat patients with major depressive disorders such as panic and social disorders. Effexor XR is available as ageneric.

What Is Celexa?

Celexa is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of not treating it. You should discuss all treatment choices with your healthcare provider. Celexa is also used to treat Major Depressive Disorder (MDD)

Talk to your healthcare provider if you do not think that your condition is getting better with Celexa treatment.

What Drugs Interact With Effexor XR?

Effexor XR may interact with other medicines that make you sleepy (such as cold orallergymedicines, sedatives, narcotics, sleeping pills, muscle relaxers, and medicines for seizures or anxiety), nonsteroidal anti-inflammatory drugs (NSAIDs),cimetidine,ketoconazole,linezolid,lithium,haloperidol,tramadol, L-tryptophan,warfarin, almotriptan, frovatriptan,sumatriptan, naratriptan, rizatriptan,zolmitriptan, other antidepressants, or other drugs.

What Drugs Interact With Celexa?

Do Not take Cymbalta if you:

  • take a Monoamine Oxidase Inhibitor (MAOI). Ask your healthcare provider or pharmacist if you are not sure if you take anMAOI, including theantibioticlinezolid or intravenousmethylene blue.
  • Do not take an MAOI within 5 days of stoppingCymbaltaunless directed to do so by your healthcare provider.
  • Do not start Cymbalta if you stopped taking an MAOI in the last 14 days unless directed to do so by your healthcare provider.

Tell your healthcare provider about all the medicines that you take,including prescription and over-the-counter medicines, vitamins, and herbal supplements. Cymbalta and some medicines may interact with each other, may not work as well, or may cause serious side effects.

Especially tell your healthcare provider if you take:

  • triptans used to treatmigraine headache
  • medicines used to treat mood, anxiety, psychotic or thought disorders, including tricyclics, lithium, buspirone, SSRIs, SNRIs or MAOIs
  • tramadol and fentanyl
  • amphetamines
  • cimetidine
  • the antibioticsciprofloxacin, enoxacin
  • medicine to treat irregular heart rate (likepropafenone,flecainide, quinidine)
  • theophylline
  • the blood thinner warfarin (Coumadin,Jantoven)
  • non-steroidal anti-inflammatory drug (NSAID) (likeibuprofen,naproxenoraspirin)。
  • over-the-counter supplements such as tryptophan or St. John's Wort
  • thioridazine(Mellaril)。Mellaril一起欣百达can cause serious heart rhythm problems or sudden death.

Ask your healthcare provider for a list of these medicines if you are not sure.

Do not take Cymbalta with any other medicine that containduloxetine.

How Should Effexor XR Be Taken?

The recommended dose of Effexor XR for most patients is 5 mg taken orally twice daily.

How Should Celexa Be Taken?

Take Celexa exactly as prescribed. Your healthcare provider may need to change the dose of Celexa until it is the right dose for you.

Celexa may be taken with or without food.

If you miss a dose of Celexa, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Celexa at the same time.

If you take too much Celexa, call your healthcare provider or poison control center right away, or get emergency treatment.

Disclaimer

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References

Pfizer. Effexor XR Drug Information.

https://www.effexorxr.com/

FDA. Celexa Drug Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020822s047lbl.pdf

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