Conjugated Linoleic Acid

Other Name(s):

Acide Linoléique Conjugué, Acide Linoléique Conjugué Cis-9,trans-11, Acide Linoléique Conjugué trans-10,cis-12, Acido Linoleico Conjugado, ALC, Cis-9,trans-11 Conjugated Linoleic Acid, Cis-Linoleic Acid,CLA, CLA-Free Fatty Acid, CLA-Triacylglycerol, LA, Linoleic Acid, Trans-10,cis-12 Conjugated Linoleic Acid.

Overview

Conjugated linoleic acid refers to a group of chemicals found in the fatty acid linoleic acid. Dairy products and beef are the major dietary sources.

共轭亚油酸是用于癌症,”努力ening of the arteries” (atherosclerosis),obesity, weight loss caused bychronic disease, bodybuilding, and limiting foodallergyreactions.

An average diet supplies 15-174 mg of conjugated linoleic acid daily.

How does it work?

Conjugated linoleic acid might help reduce body fat deposits and improve immune function.

QUESTION

What are risk factors for developing colon cancer?See Answer

Uses & Effectiveness

Possibly Effective for...

  • High blood pressure。Taking conjugated linoleic acid along with ramipril seems to reduce blood pressure more than ramipril alone in people with uncontrolledhigh blood pressure
  • Obesity。Taking conjugated linoleic acid by mouth daily might help decrease body fat in adults, but it does not seem to decrease body weight orbody mass index(BMI) in most people. Conjugated linoleic acid might reduce feelings of hunger, but it's not clear if this leads to reduced caloric intake. Taking conjugated linoleic acid does not seem to prevent weight gain in previouslyobesepeople who lost some weight.
    Adding conjugated linoleic acid to fatty foods does not seem to promote weight loss. However, adding conjugated linoleic acid to milk might help decrease body fat in obese adults.
    In children, taking 3 grams of conjugated linoleic acid daily seems to help reduce body fat.
    While conjugated linoleic acid might help reduce body weight, some research shows that taking a particular form of conjugated linoleic acid (the trans-10,cis-12 isomer) might increase risk factors for type 2 diabetes and heart disease. It's not clear whether supplements containing different forms of conjugated linoleic acid have this same risk.

Possibly Ineffective for...

  • Common cold。Research suggests that taking conjugated linoleic acid does not prevent or reduce symptoms of thecommon cold
  • Diabetes。Taking conjugated linoleic acid does not improve pre-meal or post-meal blood sugar orinsulinlevels in people withtype 2 diabetes
  • High cholesterol。Drinking milk containing conjugated linoleic acid does not seem to improve levels ofcholesterolor blood fats calledtriglyceridesin people with mildly high cholesterol levels.

Insufficient Evidence to Rate Effectiveness for...

  • Allergies (hay fever)。Taking conjugated linoleic acid for 12 weeks seems to improve well-being in people with birch allergies. However, it doesn't seem to improve overall allergy symptoms.
  • Asthma。Taking conjugated linoleic acid for 12 weeks seems to improve airway sensitivity and ability to exercise in people withasthma。However, it doesn't seem to reduce the need to use inhalers or improve lung capacity.
  • Breast cancer。共轭亚油酸的影响研究cid for preventingbreast canceris conflicting. Some early research suggests that higher intake of conjugated linoleic acid from foods, particularly cheese, seems to be linked with a lower risk of developing breast cancer. However, other research suggests that increased dietary intake of conjugated linoleic acid is not linked with a reduced risk of breast cancer. Furthermore, some research suggests that increased intake of conjugated linoleic acid might be linked with an increased risk of breast cancer.
  • Colon and rectal cancer。Some research suggests that a diet high in conjugated linoleic acid might be linked with a lower risk of cancer of thecolonandrectumin women. It is not known whether taking conjugated linoleic acid supplements provides the same benefit.
  • Strength。共轭亚油酸的影响研究cid for improving strength is conflicting. Some research shows that taking conjugated linoleic acid, alone or along with creatine and whey protein, helps increase strength and improve lean tissue mass in people who are strength training. However, other research shows that conjugated linoleic acid does not improve strength or body composition when used along with strength training.
  • Rheumatoid arthritis。Early research suggest that taking conjugated linoleic acid, alone or along with vitamin E, reduces pain and morning stiffness, as well as lab markers of swelling, compared to pretreatment in people withrheumatoid arthritis
  • Other conditions
More evidence is needed to rate conjugated linoleic acid for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate(detailed description of each of the ratings).

Side Effects

Conjugated linoleic acid isLIKELY SAFEwhen taken by mouth in amounts found in foods and isPOSSIBLY SAFEwhen taken by mouth in medicinal amounts (larger amounts than those found in food). It might cause side effects such as stomach upset, diarrhea, nausea, and fatigue.

SLIDESHOW

Digestive Disorders: Common MisconceptionsSee Slideshow

Special Precautions & Warnings

Children: Conjugated linoleic acid isPOSSIBLY SAFEfor children when taken by mouth in medicinal amounts for up to 7 months. There is not enough evidence to know if long-term use is safe.

Pregnancy and breast-feeding: Conjugated linoleic acid isLIKELY SAFEwhen taken by mouth in food amounts. But there is not enough evidence to know if conjugated linoleic acid is safe to use in medicinal mounts during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Bleeding disorders。Conjugated linoleic acid might slow blood clotting. In theory, conjugated linoleic acid might increase the risk of bruising and bleeding in people with bleeding disorders.

Diabetes: There are concerns that taking conjugated linoleic acid can worsendiabetes。Avoid use.

Metabolic syndrome: There are concerns that taking conjugated linoleic acid might increase the risk of getting diabetes if you havemetabolic syndrome。Avoid use.

Surgery: Conjugated linoleic acid might cause extra bleeding during and after surgery. Stop using it at least 2 weeks before a scheduled surgery.

Interactions


Medications for high blood pressure (Antihypertensive drugs)Interaction Rating:ModerateBe cautious with this combination.Talk with your health provider.

Conjugated linoleic acid seems to decrease blood pressure. Taking conjugated linoleic acid along with medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril),furosemide(Lasix), and many others.


Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)Interaction Rating:ModerateBe cautious with this combination.Talk with your health provider.

Conjugated linoleic acid might slow blood clotting. Taking conjugated linoleic acid along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting includeaspirin, clopidogrel (Plavix), diclofenac (Voltaren,Cataflam, others),ibuprofen(艾德维尔,布洛芬,其他)、萘普生(Anaprox,Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox),heparin, warfarin (Coumadin), and others.


Ramipril (Altace)Interaction Rating:ModerateBe cautious with this combination.Talk with your health provider.

Ramipril (Altace) is a medication used to lower blood pressure. Taking conjugated linoleic acid along with ramipril seems to increase the blood pressure-lowering effects of ramipril. In theory, taking conjugated linoleic acid plus ramipril might cause your blood pressure to go too low.

Dosing

The following doses have been studied in scientific research:

BY MOUTH

  • For reducing body fat in obese patients, a dose of 1.8 to 7 grams per day has been used. However, doses greater than 3.4 grams per day do not seem to offer any additional benefit.

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Blasi, F., Maurelli, S., Cossignani, L., D'Arco, G., Fiorini, D., Simonetti, M. S., and Damiani, P. Synthesis and Structural Analysis of Structured Triacylglycerols with CLA Isomers in the sn-2- Position. JAOCS: Journal of the American Oil Chemists' Society 2008;85(7):613-619.

Blasi, F., Maurelli, S., Cossignani, L., D'Arco, G., Simonetti, M. S., and Damiani, P. Study of Some Experimental Parameters in the Synthesis of Triacylglycerols with CLA Isomers and Structural Analysis. JAOCS: Journal of the American Oil Chemists' Society 2009;86(6):531-537.

Blasko, J., Kubinec, R., Ostrovsky, I., Pavlikova, E., Krupcik, J., and Sojak, L. Chemometric deconvolution of gas chromatographic unresolved conjugated linoleic acid isomers triplet in milk samples. J Chromatogr.A 4-3-2009;1216(14):2757-2761. View abstract.

Bocca, C., Bozzo, F., Cannito, S., Colombatto, S., and Miglietta, A. CLA reduces breast cancer cell growth and invasion through ERalpha and PI3K/Akt pathways. Chem.Biol.Interact. 1-5-2010;183(1):187-193. View abstract.

Bocca, C., Bozzo, F., Francica, S., Colombatto, S., and Miglietta, A. Involvement of PPAR gamma and E-cadherin/beta-catenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF-7 cells. Int J Cancer 7-15-2007;121(2):248-256. View abstract.

Bocca, C., Bozzo, F., Gabriel, L., and Miglietta, A. Conjugated linoleic acid inhibits Caco-2 cell growth via ERK-MAPK signaling pathway. J Nutr Biochem. 2007;18(5):332-340. View abstract.

Boeckaert, C., Vlaeminck, B., Dijkstra, J., Issa-Zacharia, A., Van Nespen, T., Van Straalen, W., and Fievez, V. Effect of dietary starch or micro algae supplementation on rumen fermentation and milk fatty acid composition of dairy cows. J Dairy Sci 2008;91(12):4714-4727. View abstract.

Bondia-Pons, I., Molto-Puigmarti, C., Castellote, A. I., and Lopez-Sabater, M. C. Determination of conjugated linoleic acid in human plasma by fast gas chromatography. J Chromatogr.A 7-20-2007;1157(1-2):422-429. View abstract.

Bonet, S. B., Quintanar, R. A., Viana, A. M., Iglesias-Gutierrez, E., and Varela-Moreiras, G. The effects of yogurt with isomer enriched conjugated linoleic acid on insulin resistance in obese adolescents. Revista Espanola de Pediatria 2008;64(1):94-100.

Bouattour, M. A., Casals, R., Albanell, E., Such, X., and Caja, G. Feeding soybean oil to dairy goats increases conjugated linoleic acid in milk. J Dairy Sci 2008;91(6):2399-2407. View abstract.

Bougnoux, P. and Menanteau, J. [Dietary fatty acids and experimental carcinogenesis]. Bull Cancer 2005;92(7):685-696. View abstract.

Bozzo, F., Bocca, C., Colombatto, S., and Miglietta, A. Antiproliferative effect of conjugated linoleic acid in caco-2 cells: involvement of PPARgamma and APC/beta-catenin pathways. Chem.Biol.Interact. 8-30-2007;169(2):110-121. View abstract.

Bretillon, L., Chardigny, J. M., Gregoire, S., Berdeaux, O., and Sebedio, J. L. Effects of conjugated linoleic acid isomers on the hepatic microsomal desaturation activities in vitro. Lipids 1999;34(9):965-969. View abstract.

布劳顿,k . S。规则,d . C。你们,Y。,,X。,Driscoll, M., and Culver, B. Dietary omega-3 fatty acids differentially influence ova release and ovarian cyclooxygenase-1 and cyclooxygenase-2 expression in rats. Nutr Res 2009;29(3):197-205. View abstract.

Brouwer, I. A., Wanders, A. J., and Katan, M. B. Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans--a quantitative review. PLoS.One. 2010;5(3):e9434. View abstract.

Brown, J. M. and McIntosh, M. K. Conjugated linoleic acid in humans: regulation of adiposity and insulin sensitivity. J Nutr 2003;133(10):3041-3046. View abstract.

Brown, J. M., Boysen, M. S., Chung, S., Fabiyi, O., Morrison, R. F., Mandrup, S., and McIntosh, M. K. Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines. J Biol Chem 6-18-2004;279(25):26735-26747. View abstract.

Brown, J. M., Boysen, M. S., Jensen, S. S., Morrison, R. F., Storkson, J., Lea-Currie, R., Pariza, M., Mandrup, S., and McIntosh, M. K. Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes. J Lipid Res 2003;44(7):1287-1300. View abstract.

Brown, J. M., Halvorsen, Y. D., Lea-Currie, Y. R., Geigerman, C., and McIntosh, M. Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue. J Nutr 2001;131(9):2316-2321. View abstract.

Brownbill, R. A., Petrosian, M., and Ilich, J. Z. Association between dietary conjugated linoleic acid and bone mineral density in postmenopausal women. J Am Coll Nutr 2005;24(3):177-181. View abstract.

Bu, D. P., Wang, J. Q., Dhiman, T. R., and Liu, S. J. Effectiveness of oils rich in linoleic and linolenic acids to enhance conjugated linoleic acid in milk from dairy cows. J Dairy Sci 2007;90(2):998-1007. View abstract.

Burdge, G. C., Lupoli, B., Russell, J. J., Tricon, S., Kew, S., Banerjee, T., Shingfield, K. J., Beever, D. E., Grimble, R. F., Williams, C. M., Yaqoob, P., and Calder, P. C. Incorporation of cis-9,trans-11 or trans-10,cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men. J Lipid Res 2004;45(4):736-741. View abstract.

Burdge, G. C., Tricon, S., Morgan, R., Kliem, K. E., Childs, C., Jones, E., Russell, J. J., Grimble, R. F., Williams, C. M., Yaqoob, P., and Calder, P. C. Incorporation of cis-9, trans-11 conjugated linoleic acid and vaccenic acid (trans-11 18 : 1) into plasma and leucocyte lipids in healthy men consuming dairy products naturally enriched in these fatty acids. Br J Nutr 2005;94(2):237-243. View abstract.

Butz, D. E., Li, G., Huebner, S. M., and Cook, M. E. A mechanistic approach to understanding conjugated linoleic acid's role in inflammation using murine models of rheumatoid arthritis. Am.J Physiol Regul.Integr.Comp Physiol 2007;293(2):R669-R676. View abstract.

Byeon, J. I., Song, H. S., Oh, T. W., Kim, Y. S., Choi, B. D., Kim, H. C., Kim, J. O., Shim, K. H., and Ha, Y. L. Growth inhibition of foodborne and pathogenic bacteria by conjugated linoleic acid. J Agric.Food Chem. 4-22-2009;57(8):3164-3172. View abstract.

Campbell, B. and Kreider, R. B. Conjugated linoleic acids. Curr Sports Med Rep. 2008;7(4):237-241. View abstract.

Cao, Y., Chen, J., Yang, L., and Chen, Z. Y. Differential incorporation of dietary conjugated linolenic and linoleic acids into milk lipids and liver phospholipids in lactating and suckling rats. J Nutr Biochem. 2009;20(9):685-693. View abstract.

Cao, Z. P., Wang, F., Xiang, X. S., Cao, R., Zhang, W. B., and Gao, S. B. Intracerebroventricular administration of conjugated linoleic acid (CLA) inhibits food intake by decreasing gene expression of NPY and AgRP. Neurosci.Lett. 5-18-2007;418(3):217-221. View abstract.

Caroprese, M,马沙诺,一个马里诺,R, Gliatta G。, Muscio, A., and Sevi, A. Flaxseed supplementation improves fatty acid profile of cow milk. J Dairy Sci 2010;93(6):2580-2588. View abstract.

Carriquiry, M., Weber, W. J., Dahlen, C. R., Lamb, G. C., Baumgard, L. H., and Crooker, B. A. Fatty acid composition of milk from multiparous Holstein cows treated with bovine somatotropin and fed n-3 fatty acids in early lactation. J Dairy Sci 2009;92(10):4865-4875. View abstract.

Castaneda-Gutierrez, E., Benefield, B. C., de Veth, M. J., Santos, N. R., Gilbert, R. O., Butler, W. R., and Bauman, D. E. Evaluation of the mechanism of action of conjugated linoleic acid isomers on reproduction in dairy cows. J Dairy Sci 2007;90(9):4253-4264. View abstract.

Castellanos-Tapia, L., Yepiz-Plasencia, G., and Moya-Camarenaa, S. Y. Dietary conjugated linoleic acid induces tissue-specific lipoprotein lipase mRNA modulation in high-sucrose-fed mice. Ann.Nutr Metab 2009;54(2):131-137. View abstract.

Chae, S. H., Keeton, J. T., Miller, R. K., Johnson, D., Maxim, J., and Smith, S. B. The triacylglycerol preparation of conjugated linoleic acid reduces lipid oxidation in irradiated, cooked ground beef patties. Meat.Sci 11-12-2008; View abstract.

Lavillonniere Chajes, V, F。,法拉利,Jourda Pn, M. L., Pinault, M., Maillard, V., Sebedio, J. L., and Bougnoux, P. Conjugated linoleic acid and the risk of breast cancer. IARC Sci Publ. 2002;156:203-204. View abstract.

Lavillonniere Chajes, V, F。,法拉利,Jourda Pn, M. L., Pinault, M., Maillard, V., Sebedio, J. L., and Bougnoux, P. Conjugated linoleic acid content in breast adipose tissue is not associated with the relative risk of breast cancer in a population of French patients. Cancer Epidemiol.Biomarkers Prev. 2002;11(7):672-673. View abstract.

Changhua, L., Jindong, Y., Defa, L., Lidan, Z., Shiyan, Q., and Jianjun, X. Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide. J Nutr 2005;135(2):239-244. View abstract.

Chao, P. M., Chen, W. H., Liao, C. H., and Shaw, H. M. Conjugated linoleic acid causes a marked increase in liver alpha-tocopherol and liver alpha-tocopherol transfer protein in C57BL/6 J mice. Int J Vitam.Nutr Res 2010;80(1):65-73. View abstract.

Chapkin, R. S., McMurray, D. N., Davidson, L. A., Patil, B. S., Fan, Y. Y., and Lupton, J. R. Bioactive dietary long-chain fatty acids: emerging mechanisms of action. Br.J Nutr 2008;100(6):1152-1157. View abstract.

Chartrand, R., Matte, J. J., Lessard, M., Chouinard, P. Y., Giguere, A., and Laforest, J. P. Effect of dietary fat sources on systemic and intrauterine synthesis of prostaglandins during early pregnancy in gilts. J Anim Sci 2003;81(3):726-734. View abstract.

Chen, B., Guo, Z., Let, M. B., Lue, B. M., and Xu, X. Preparation of CLA ascorbyl ester with improved volumetric productivity by an ionic liquid-based reaction system. Org.Biomol.Chem. 9-7-2008;6(17):3196-3201. View abstract.

Chen, H., Xu, Q., Ye, Q., Chen, W., and Zhang, H. [Bioconversion kinetics of conjugated linoleic acid by Lactobacillus plantarum ZS2058]. Wei Sheng Wu Xue.Bao. 2-4-2009;49(2):174-179. View abstract.

Chen, J. Src may be involved in the anti-cancer effect of conjugated linoleic acid. Comment on: CLA reduces breast cancer cell growth and invasion through ER and PI3K/Akt pathways. Chem.Biol.Interact. 7-30-2010;186(2):250-251. View abstract.

Chen, X. J., Mao, H. L., Ma, X. M., and Liu, J. X. Effects of dietary corn oil and vitamin E supplementation on fatty acid profiles and expression of acetyl CoA carboxylase and stearoyl-CoA desaturase gene in Hu sheep. Anim Sci J 2010;81(2):165-171. View abstract.

Traber, Cherian G m·G。Goeger, m . P。,狮子座nard, S. W. Conjugated linoleic acid and fish oil in laying hen diets: effects on egg fatty acids, thiobarbituric acid reactive substances, and tocopherols during storage. Poult.Sci 2007;86(5):953-958. View abstract.

Chilliard, Y., Martin, C., Rouel, J., and Doreau, M. Milk fatty acids in dairy cows fed whole crude linseed, extruded linseed, or linseed oil, and their relationship with methane output. J Dairy Sci 2009;92(10):5199-5211. View abstract.

Cho, H. J., Kim, E. J., Lim, S. S., Kim, M. K., Sung, M. K., Kim, J. S., and Park, J. H. Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid inhibits G1-S progression in HT-29 human colon cancer cells. J Nutr 2006;136(4):893-898. View abstract.

Cho, H. J., Kim, W. K., Jung, J. I., Kim, E. J., Lim, S. S., Kwon, D. Y., and Park, J. H. Trans-10,cis-12, not cis-9,trans-11, conjugated linoleic acid decreases ErbB3 expression in HT-29 human colon cancer cells. World J Gastroenterol 9-7-2005;11(33):5142-5150. View abstract.

Cho, H. J., Kim, W. K., Kim, E. J., Jung, K. C., Park, S., Lee, H. S., Tyner, A. L., and Park, J. H. Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line. Am J Physiol Gastrointest.Liver Physiol 2003;284(6):G996-1005. View abstract.

Cho, H. J., Kwon, G. T., and Park, J. H. trans-10,cis-12 Conjugated linoleic acid induces depolarization of mitochondrial membranes in HT-29 human colon cancer cells: a possible mechanism for induction of apoptosis. J Med Food 2009;12(5):952-958. View abstract.

Cho, H. J., Lee, H. S., Chung, C. K., Kang, Y. H., Ha, Y. L., Park, H. S., and Park, J. H. trans-10, cis-12 conjugated linoleic acid reduces insulin-like growth factor-II secretion in HT-29 human colon cancer cells. J Med Food 2003;6(3):193-199. View abstract.

Cho, M. H., Kang, J. H., and Yang, M. P. Immunoenhancing effect of trans-10, cis-12 conjugated linoleic acid on the phagocytic capacity and oxidative burst activity of canine peripheral blood phagocytes. Res Vet.Sci 2008;85(2):269-278. View abstract.

Choi, J. S., Jung, M. H., Park, H. S., and Song, J. Effect of conjugated linoleic acid isomers on insulin resistance and mRNA levels of genes regulating energy metabolism in high-fat-fed rats. Nutrition 2004;20(11-12):1008-1017. View abstract.

Choi, J. S., Koh, I. U., Jung, M. H., and Song, J. Effects of three different conjugated linoleic acid preparations on insulin signalling, fat oxidation and mitochondrial function in rats fed a high-fat diet. Br.J Nutr 2007;98(2):264-275. View abstract.

Choi, N. J., Park, H. G., Kim, J. H., Hwang, H. J., Kwon, K. H., Yoon, J. A., Kwon, E. G., Chang, J., Hwang, I. H., and Kim, Y. J. Characterizations of environmental factors in conjugated linoleic acid production by mixed rumen bacteria. J Agric.Food Chem. 10-14-2009;57(19):9263-9267. View abstract.

Choi, N. J., Park, H. G., Kim, Y. J., Kim, I. H., Kang, H. S., Yoon, C. S., Yoon, H. G., Park, S. I., Lee, J. W., and Chung, S. H. Utilization of monolinolein as a substrate for conjugated linoleic acid production by Bifidobacterium breve LMC 520 of human neonatal origin. J Agric.Food Chem. 11-26-2008;56(22):10908-10912. View abstract.

Choi, Y., Park, Y., Pariza, M. W., and Ntambi, J. M. Regulation of stearoyl-CoA desaturase activity by the trans-10,cis-12 isomer of conjugated linoleic acid in HepG2 cells. Biochem Biophys Res Commun. 6-15-2001;284(3):689-693. View abstract.

Choi, Y., Park, Y., Storkson, J. M., Pariza, M. W., and Ntambi, J. M. Inhibition of stearoyl-CoA desaturase activity by the cis-9,trans-11 isomer and the trans-10,cis-12 isomer of conjugated linoleic acid in MDA-MB-231 and MCF-7 human breast cancer cells. Biochem Biophys Res Commun. 6-21-2002;294(4):785-790. View abstract.

Choy, J. H., Shin, J., Lim, S. Y., Oh, J. M., Oh, M. H., and Oh, S. Characterization and stability analysis of zinc oxide nanoencapsulated conjugated linoleic Acid. J Food Sci 8-1-2010;75(6):N63-N68. View abstract.

Christie, W. W., Dobson, G., and Adlof, R. O. A practical guide to the isolation, analysis and identification of conjugated linoleic acid. Lipids 2007;42(12):1073-1084. View abstract.

Christy, A. A. Evidence in the formation of conjugated linoleic acids from thermally induced 9t12t linoleic acid: a study by gas chromatography and infrared spectroscopy. Chem.Phys.Lipids 2009;161(2):86-94. View abstract.

Christy, A. A. Isomerization of 9c11t/10t12c CLA in triacylglycerols. Lipids 2010;45(8):733-741. View abstract.

Chuang, L. T., Leonard, A. E., Liu, J. W., Mukerji, P., Bray, T. M., and Huang, Y. S. Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase. Lipids 2001;36(10):1099-1103. View abstract.

Chujo, H., Yamasaki, M., Nou, S., Koyanagi, N., Tachibana, H., and Yamada, K. Effect of conjugated linoleic acid isomers on growth factor-induced proliferation of human breast cancer cells. Cancer Lett 12-8-2003;202(1):81-87. View abstract.

涌,S . H。金,即H,公园,H·G。康,H·S。, Yoon, C. S., Jeong, H. Y., Choi, N. J., Kwon, E. G., and Kim, Y. J. Synthesis of conjugated linoleic acid by human-derived Bifidobacterium breve LMC 017: utilization as a functional starter culture for milk fermentation. J Agric.Food Chem. 5-14-2008;56(9):3311-3316. View abstract.

Chung, S., Brown, J. M., Provo, J. N., Hopkins, R., and McIntosh, M. K. Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production. J Biol Chem 11-18-2005;280(46):38445-38456. View abstract.

Chung, S., Brown, J. M., Sandberg, M. B., and McIntosh, M. Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling. J Lipid Res 2005;46(5):885-895. View abstract.

Chung, S., Park, S., and Yang, C. H. Unsaturated fatty acids bind Myc-Max transcription factor and inhibit Myc-Max-DNA complex formation. Cancer Lett 12-15-2002;188(1-2):153-162. View abstract.

Churruca, I., Fernandez-Quintela, A., and Portillo, M. P. Conjugated linoleic acid isomers: differences in metabolism and biological effects. Biofactors 2009;35(1):105-111. View abstract.

Churruca, I., Fernandez-Quintela, A., Zabala, A., Macarulla, M. T., Navarro, V., Rodriguez, V. M., Simon, E., Milagro, F., and Portillo, M. P. The effect of trans-10,cis-12 conjugated linoleic acid on lipogenesis is tissue dependent in hamsters. Genes Nutr 2007;2(1):121-123. View abstract.

Cimini, A。,c、L。Colafarina, Benedet年代ti, E., Di Loreto, S., Festuccia, C., Amicarelli, F., Canuto, R. A., and Ceru, M. P. PPARgamma-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF). Int J Cancer 12-20-2005;117(6):923-933. View abstract.

Clement, L., Poirier, H., Niot, I., Bocher, V., Guerre-Millo, M., Krief, S., Staels, B., and Besnard, P. Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. J Lipid Res 2002;43(9):1400-1409. View abstract.

Close, R. N., Schoeller, D. A., Watras, A. C., and Nora, E. H. Conjugated linoleic acid supplementation alters the 6-mo change in fat oxidation during sleep. Am.J Clin.Nutr 2007;86(3):797-804. View abstract.

Coakley, M., Barrett, E., Murphy, J. J., Ross, R. P., Devery, R., and Stanton, C. Cheese manufacture with milk with elevated conjugated linoleic acid levels caused by dietary manipulation. J Dairy Sci 2007;90(6):2919-2927. View abstract.

Coakley, M., Ross, R. P., Nordgren, M., Fitzgerald, G., Devery, R., and Stanton, C. Conjugated linoleic acid biosynthesis by human-derived Bifidobacterium species. J Appl Microbiol. 2003;94(1):138-145. View abstract.

Colakoglu, S., Colakoglu, M., Taneli, F., Cetinoz, F., and Turkmen, M. Cumulative effects of conjugated linoleic acid and exercise on endurance development, body composition, serum leptin and insulin levels. J.Sports Med.Phys.Fitness 2006;46(4):570-577. View abstract.

Cook, M. E., Miller, C. C., Park, Y., and Pariza, M. Immune modulation by altered nutrient metabolism: nutritional control of immune-induced growth depression. Poult.Sci 1993;72(7):1301-1305. View abstract.

Cooper, M. H., Miller, J. R., Mitchell, P. L., Currie, D. L., and McLeod, R. S. Conjugated linoleic acid isomers have no effect on atherosclerosis and adverse effects on lipoprotein and liver lipid metabolism in apoE-/- mice fed a high-cholesterol diet. Atherosclerosis 2008;200(2):294-302. View abstract.

Cordero, G., Isabel, B., Menoyo, D., Daza, A., Morales, J., Pineiro, C., and Lopez-Bote, C. J. Dietary CLA alters intramuscular fat and fatty acid composition of pig skeletal muscle and subcutaneous adipose tissue. Meat.Sci 2010;85(2):235-239. View abstract.

Corino, C., Di Giancamillo, A., Rossi, R., and Domeneghini, C. Dietary conjugated linoleic acid affects morphofunctional and chemical aspects of subcutaneous adipose tissue in heavy pigs. J Nutr 2005;135(6):1444-1450. View abstract.

Corino, C., Pastorelli, G., Rosi, F., Bontempo, V., and Rossi, R. Effect of dietary conjugated linoleic acid supplementation in sows on performance and immunoglobulin concentration in piglets. J Anim Sci 2009;87(7):2299-2305. View abstract.

Corl, B. A., Barbano, D. M., Bauman, D. E., and Ip, C. cis-9, trans-11 CLA derived endogenously from trans-11 18:1 reduces cancer risk in rats. J Nutr 2003;133(9):2893-2900. View abstract.

Cornish, S. M., Candow, D. G., Jantz, N. T., Chilibeck, P. D., Little, J. P., Forbes, S., Abeysekara, S., and Zello, G. A. Conjugated linoleic acid combined with creatine monohydrate and whey protein supplementation during strength training. Int J Sport Nutr Exerc.Metab 2009;19(1):79-96. View abstract.

Cortes, C., Silva-Kazama, D. C., Kazama, R., Gagnon, N., Benchaar, C., Santos, G. T., Zeoula, L. M., and Petit, H. V. Milk composition, milk fatty acid profile, digestion, and ruminal fermentation in dairy cows fed whole flaxseed and calcium salts of flaxseed oil. J Dairy Sci 2010;93(7):3146-3157. View abstract.

Crisa, A., Marchitelli, C., Pariset, L., Contarini, G., Signorelli, F., Napolitano, F., Catillo, G., Valentini, A., and Moioli, B. Exploring polymorphisms and effects of candidate genes on milk fat quality in dairy sheep. J Dairy Sci 2010;93(8):3834-3845. View abstract.

Cruz-Hernandez, C., Kramer, J. K., Kennelly, J. J., Glimm, D. R., Sorensen, B. M., Okine, E. K., Goonewardene, L. A., and Weselake, R. J. Evaluating the conjugated linoleic acid and trans 18:1 isomers in milk fat of dairy cows fed increasing amounts of sunflower oil and a constant level of fish oil. J Dairy Sci 2007;90(8):3786-3801. View abstract.

坎宁安,d . C,哈里森,l . Y。舒尔茨,T。D. Proliferative responses of normal human mammary and MCF-7 breast cancer cells to linoleic acid, conjugated linoleic acid and eicosanoid synthesis inhibitors in culture. Anticancer Res 1997;17(1A):197-203. View abstract.

Cusack, S., Jewell, C., and Cashman, K. D. The effect of conjugated linoleic acid on the viability and metabolism of human osteoblast-like cells. Prostaglandins Leukot.Essent.Fatty Acids 2005;72(1):29-39. View abstract.

D'Urso, S., Cutrignelli, M. I., Calabro, S., Bovera, F., Tudisco, R., Piccolo, V., and Infascelli, F. Influence of pasture on fatty acid profile of goat milk. J Anim Physiol Anim Nutr (Berl) 2008;92(3):405-410. View abstract.

Daley, C. A., Abbott, A., Doyle, P. S., Nader, G. A., and Larson, S. A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef. Nutr J 2010;9:10. View abstract.

Dancu, M. B., Berardi, D. E., Vanden Heuvel, J. P., and Tarbell, J. M. Atherogenic Endothelial Cell eNOS and ET-1 Responses to Asynchronous Hemodynamics are Mitigated by Conjugated Linoleic Acid. Ann.Biomed.Eng 2007;35(7):1111-1119. View abstract.

Darestani, A. T., Hosseinpanah, F., Tahbaz, F., Amiri, Z., Darestani, R. T., and Hedayati, M. Effects of conjugated linoleic acid supplementation on body composition and leptin concentration in post-menopausal women. Iranian Journal of Endocrinology & Metabolism 2010;12(1):84.

Dauchy, R. T., Blask, D. E., Sauer, L. A., Davidson, L. K., Krause, J. A., Smith, L. C., and Dauchy, E. M. Physiologic melatonin concentration, omega-3 fatty acids, and conjugated linoleic acid inhibit fatty acid transport in rodent hind limb skeletal muscle in vivo. Comp Med 2003;53(2):186-190. View abstract.

Dauchy, R. T., Dauchy, E. M., Davidson, L. K., Krause, J. A., Lynch, D. T., Tirrell, P. C., Tirrell, R. P., Sauer, L. A., Van der, Riet P., and Blask, D. E. Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids. Comp Med 2007;57(4):377-382. View abstract.

Dauchy, R. T., Dauchy, E. M., Sauer, L. A., Blask, D. E., Davidson, L. K., Krause, J. A., and Lynch, D. T. Differential inhibition of fatty acid transport in tissue-isolated steroid receptor negative human breast cancer xenografts perfused in situ with isomers of conjugated linoleic acid. Cancer Lett 6-8-2004;209(1):7-15. View abstract.

de Deckere, E. A., van Amelsvoort, J. M., McNeill, G. P., and Jones, P. Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. Br J Nutr 1999;82(4):309-317. View abstract.

De La Fuente, L. F., Barbosa, E., Carriedo, J. A., Gonzalo, C., Arenas, R., Fresno, J. M., and San Primitivo, F. Factors influencing variation of fatty acid content in ovine milk. J Dairy Sci 2009;92(8):3791-3799. View abstract.

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de Veth, M. J., Bauman, D. E., Koch, W., Mann, G. E., Pfeiffer, A. M., and Butler, W. R. Efficacy of conjugated linoleic acid for improving reproduction: a multi-study analysis in early-lactation dairy cows. J Dairy Sci 2009;92(6):2662-2669. View abstract.

DeClercq, V., Zahradka, P., and Taylor, C. G. Dietary t10,c12-CLA but not c9,t11 CLA reduces adipocyte size in the absence of changes in the adipose renin-angiotensin system in fa/fa Zucker rats. Lipids 2010;45(11):1025-1033. View abstract.

Degner, S. C., Kemp, M. Q., Bowden, G. T., and Romagnolo, D. F. Conjugated linoleic acid attenuates cyclooxygenase-2 transcriptional activity via an anti-AP-1 mechanism in MCF-7 breast cancer cells. J Nutr 2006;136(2):421-427. View abstract.

Degner, S. C., Kemp, M. Q., Hockings, J. K., and Romagnolo, D. F. Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer mcf-7 cells: repressive effects of conjugated linoleic acid. Nutr Cancer 2007;59(2):248-257. View abstract.

Degrace, P., Demizieux, L., Gresti, J., Chardigny, J. M., Sebedio, J. L., and Clouet, P. Hepatic steatosis is not due to impaired fatty acid oxidation capacities in C57BL/6J mice fed the conjugated trans-10,cis-12-isomer of linoleic acid. J Nutr 2004;134(4):861-867. View abstract.

Dehkordi, S. K., Vlaeminck, B., Hostens, M., Opsomer, G., and Fievez, V. In vitro rumen biohydrogenation of trans-10, cis-12 conjugated linoleic acid in a lipid-encapsulated (LE-CLA) supplement incorporated or not in a processing pellet. Commun.Agric.Appl.Biol.Sci 2008;73(1):119-122. View abstract.

DeLany, J. P. and West, D. B. Changes in body composition with conjugated linoleic acid. J Am Coll Nutr 2000;19(4):487S-493S. View abstract.

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Demaree, S. R., Gilbert, C. D., Mersmann, H. J., and Smith, S. B. Conjugated linoleic acid differentially modifies fatty acid composition in subcellular fractions of muscle and adipose tissue but not adiposity of postweaning pigs. J Nutr 2002;132(11):3272-3279. View abstract.

Demir, A. S. and Talpur, F. N. Chemoenzymatic conversion of linoleic acid into conjugated linoleic acid. J Agric.Food Chem. 2-10-2010;58(3):1646-1652. View abstract.

Deng, M. D., Grund, A. D., Schneider, K. J., Langley, K. M., Wassink, S. L., Peng, S. S., and Rosson, R. A. Linoleic acid isomerase from Propionibacterium acnes: purification, characterization, molecular cloning, and heterologous expression. Appl.Biochem.Biotechnol. 2007;143(3):199-211. View abstract.

desBordes, C. and Lea, M. A. Effects of C18 fatty acid isomers on DNA synthesis in hepatoma and breast cancer cells. Anticancer Res 1995;15(5B):2017-2021. View abstract.

Desroches, S., Chouinard, P. Y., Galibois, I., Corneau, L., Delisle, J., Lamarche, B., Couture, P., and Bergeron, N. Lack of effect of dietary conjugated linoleic acids naturally incorporated into butter on the lipid profile and body composition of overweight and obese men. Am J Clin Nutr 2005;82(2):309-319. View abstract.

Devery, R., Miller, A., and Stanton, C. Conjugated linoleic acid and oxidative behaviour in cancer cells. Biochem Soc Trans 2001;29(Pt 2):341-344. View abstract.

Devillard, E., McIntosh, F. M., Duncan, S. H., and Wallace, R. J. Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid. J Bacteriol. 2007;189(6):2566-2570. View abstract.

麦金托什Devillard E, f . M。主料,D,托姆as, N. A., Shingfield, K. J., and Wallace, R. J. Differences between human subjects in the composition of the faecal bacterial community and faecal metabolism of linoleic acid. Microbiology 2009;155(Pt 2):513-520. View abstract.

Dhiman, T. R., Nam, S. H., and Ure, A. L. Factors affecting conjugated linoleic acid content in milk and meat. Crit Rev Food Sci Nutr 2005;45(6):463-482. View abstract.

Di Giancamillo, A., Rossi, R., Vitari, F., Pastorelli, G., Corino, C., and Domeneghini, C. Dietary conjugated linoleic acids decrease leptin in porcine adipose tissue. J Nutr 2009;139(10):1867-1872. View abstract.

Di, Felice, V, Macaluso, F., Montalbano, A., Gammazza, A. M., Palumbo, D., Angelone, T., Bellafiore, M., and Farina, F. Effects of conjugated linoleic acid and endurance training on peripheral blood and bone marrow of trained mice. J Strength.Cond.Res 2007;21(1):193-198. View abstract.

Diaz, M. L., Watkins, B. A., Li, Y., Anderson, R. A., and Campbell, W. W. Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women. J.Nutr.Biochem. 2008;19(1):61-68. View abstract.

Diez, A., Menoyo, D., Perez-Benavente, S., Calduch-Giner, J. A., Vega-Rubin, de Celis, Obach, A., Favre-Krey, L., Boukouvala, E., Leaver, M. J., Tocher, D. R., Perez-Sanchez, J., Krey, G., and Bautista, J. M. Conjugated linoleic acid affects lipid composition, metabolism, and gene expression in gilthead sea bream (Sparus aurata L). J Nutr 2007;137(6):1363-1369. View abstract.

Diniz, y。,桑托斯·P。Assalin, Souza h . B, G. A., Rocha, K. K., Ebaid, G. M., Seiva, F. R., Amauchi, J. F., Novelli Filho, J. L., and Novelli, E. L. Conjugated linoleic acid and cardiac health: oxidative stress and energetic metabolism in standard and sucrose-rich diets. Eur J Pharmacol. 1-28-2008;579(1-3):318-325. View abstract.

Donnelly, C., Olsen, A. M., Lewis, L. D., Eisenberg, B. L., Eastman, A., and Kinlaw, W. B. Conjugated linoleic acid (CLA) inhibits expression of the Spot 14 (THRSP) and fatty acid synthase genes and impairs the growth of human breast cancer and liposarcoma cells. Nutr Cancer 2009;61(1):114-122. View abstract.

Drouin, G., Douillette, A., Lacasse, P., and Paquette, B. [Radiosensitizing effect of conjugated linoleic acid on tumor cells MCF-7 and MDA-MB-231]. Can.J Physiol Pharmacol 2004;82(2):94-102. View abstract.

Drury, B., Warford-Woolgar, L. J., Herchak, D. J., Bankovic-Calic, N., Crow, G., Taylor, C. G., Zahradka, P., Ogborn, M. R., and Aukema, H. M. Dietary trans-10, cis-12 conjugated linoleic acid reduces early glomerular enlargement and elevated renal cyclooxygenase-2 levels in young obese fa/fa zucker rats. J Nutr 2009;139(2):285-290. View abstract.

Duckett, S. K. and Gillis, M. H. Effects of oil source and fish oil addition on ruminal biohydrogenation of fatty acids and conjugated linoleic acid formation in beef steers fed finishing diets. J Anim Sci 2010;88(8):2684-2691. View abstract.

Duckett, S. K., Neel, J. P., Fontenot, J. P., and Clapham, W. M. Effects of winter stocker growth rate and finishing system on: III. Tissue proximate, fatty acid, vitamin, and cholesterol content. J Anim Sci 2009;87(9):2961-2970. View abstract.

Dugan, M. E., Aldai, N., Kramer, J. K., Gibb, D. J., Juarez, M., and McAllister, T. A. Feeding wheat dried distillers grains with solubles improves beef trans and conjugated linoleic acid profiles. J Anim Sci 2010;88(5):1842-1847. View abstract.

Dugan, M. E., Kramer, J. K., Robertson, W. M., Meadus, W. J., Aldai, N., and Rolland, D. C. Comparing subcutaneous adipose tissue in beef and muskox with emphasis on trans 18:1 and conjugated linoleic acids. Lipids 2007;42(6):509-518. View abstract.

Durgam, V. R. and Fernandes, G. The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system. Cancer Lett 6-24-1997;116(2):121-130. View abstract.

Dyck, D. J. Dietary fat intake, supplements, and weight loss. Can J Appl.Physiol 2000;25(6):495-523. View abstract.

Ealey, K. N., El Sohemy, A., and Archer, M. C. Conjugated linoleic acid does not inhibit development of aberrant crypt foci in colons of male Sprague-Dawley rats. Nutr Cancer 2001;41(1-2):104-106. View abstract.

Ealey, K. N., El Sohemy, A., and Archer, M. C. Effects of dietary conjugated linoleic acid on the expression of uncoupling proteins in mice and rats. Lipids 2002;37(9):853-861. View abstract.

Ecker, J., Liebisch, G., Patsch, W., and Schmitz, G. The conjugated linoleic acid isomer trans-9,trans-11 is a dietary occurring agonist of liver X receptor alpha. Biochem.Biophys.Res Commun. 10-30-2009;388(4):660-666. View abstract.

Ecker, J., Liebisch, G., Scherer, M., and Schmitz, G. Differential effects of conjugated linoleic acid isomers on macrophage glycerophospholipid metabolism. J Lipid Res 2010;51(9):2686-2694. View abstract.

Eder, K. and Ringseis, R. Metabolism and actions of conjugated linoleic acids on atherosclerosis-related events in vascular endothelial cells and smooth muscle cells. Mol.Nutr Food Res 2010;54(1):17-36. View abstract.

Eder, K., Slomma, N., and Becker, K. Trans-10,cis-12 conjugated linoleic acid suppresses the desaturation of linoleic and alpha-linolenic acids in HepG2 cells. J Nutr 2002;132(6):1115-1121. View abstract.

Eggert, J. M., Belury, M. A., Kempa-Steczko, A., Mills, S. E., and Schinckel, A. P. Effects of conjugated linoleic acid on the belly firmness and fatty acid composition of genetically lean pigs. J Anim Sci 2001;79(11):2866-2872. View abstract.

Egras, A. M., Hamilton, W. R., Lenz, T. L., and Monaghan, M. S. An evidence-based review of fat modifying supplemental weight loss products. J Obes. 2011;2011 View abstract.

Emken, E. A., Adlof, R. O., Duval, S., Nelson, G., and Benito, P. Effect of dietary conjugated linoleic acid (CLA) on metabolism of isotope-labeled oleic, linoleic, and CLA isomers in women. Lipids 2002;37(8):741-750. View abstract.

Erickson, K. L. and Hubbard, N. E. Fatty acids and breast cancer: the role of stem cells. Prostaglandins Leukot.Essent.Fatty Acids 2010;82(4-6):237-241. View abstract.

Escrich, E., Moral, R., Grau, L., Costa, I., and Solanas, M. Molecular mechanisms of the effects of olive oil and other dietary lipids on cancer. Mol.Nutr Food Res 2007;51(10):1279-1292. View abstract.

Evans, N. P., Misyak, S. A., Schmelz, E. M., Guri, A. J., Hontecillas, R., and Bassaganya-Riera, J. Conjugated linoleic acid ameliorates inflammation-induced colorectal cancer in mice through activation of PPARgamma. J Nutr 2010;140(3):515-521. View abstract.

Ewaschuk, J. B., Walker, J. W., Diaz, H., and Madsen, K. L. Bioproduction of conjugated linoleic acid by probiotic bacteria occurs in vitro and in vivo in mice. J Nutr 2006;136(6):1483-1487. View abstract.

Eyjolfson, V., Spriet, L. L., and Dyck, D. J. Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans. Med Sci Sports Exerc. 2004;36(5):814-820. View abstract.

Eynard, A. R. and Lopez, C. B. Conjugated linoleic acid (CLA) versus saturated fats/cholesterol: their proportion in fatty and lean meats may affect the risk of developing colon cancer. Lipids Health Dis. 8-29-2003;2:6. View abstract.

Fagali, N. and Catala, A. Antioxidant activity of conjugated linoleic acid isomers, linoleic acid and its methyl ester determined by photoemission and DPPH techniques. Biophys.Chem. 2008;137(1):56-62. View abstract.

e·R。落寞Chouinard, y P,雅克·H。Venkatramanan, S., Maf, A. A., Defnoun, S., and Jones, P. J. The effect of drinking milk containing conjugated linoleic acid on fecal microbiological profile, enzymatic activity, and fecal characteristics in humans. Nutr J 2007;6:15. View abstract.

Feng, Y. and Cronan, J. E. A new member of the Escherichia coli fad regulon: transcriptional regulation of fadM (ybaW). J Bacteriol. 2009;191(20):6320-6328. View abstract.

Field, C. J. and Schley, P. D. Evidence for potential mechanisms for the effect of conjugated linoleic acid on tumor metabolism and immune function: lessons from n-3 fatty acids. Am J Clin Nutr 2004;79(6 Suppl):1190S-1198S. View abstract.

Fincham, J. R., Fontenot, J. P., Swecker, W. S., Herbein, J. H., Neel, J. P., Scaglia, G., Clapham, W. M., and Notter, D. R. Fatty acid metabolism and deposition in subcutaneous adipose tissue of pasture- and feedlot-finished cattle. J Anim Sci 2009;87(10):3259-3277. View abstract.

Fischer-Posovszky, P., Kukulus, V., and Wabitsch, M. [Conjugated linoleic acids (CLA) and their relevance in the reduction of body fat. A critical review of the currently available data]. MMW.Fortschr.Med 1-17-2008;149 Suppl 4:128-131. View abstract.

Fischer-Posovszky, P., Kukulus, V., Zulet, M. A., Debatin, K. M., and Wabitsch, M. Conjugated linoleic acids promote human fat cell apoptosis. Horm.Metab Res 2007;39(3):186-191. View abstract.

Flickinger, B. D. and Huth, P. J. Dietary fats and oils: technologies for improving cardiovascular health. Curr.Atheroscler.Rep. 2004;6(6):468-476. View abstract.

Flowers, G., Ibrahim, S. A., and AbuGhazaleh, A. A. Milk fatty acid composition of grazing dairy cows when supplemented with linseed oil. J Dairy Sci 2008;91(2):722-730. View abstract.

Flowers, M. and Thompson, P. A. t10c12 conjugated linoleic acid suppresses HER2 protein and enhances apoptosis in SKBr3 breast cancer cells: possible role of COX2. PLoS.One. 2009;4(4):e5342. View abstract.

Flowers, M., Schroeder, J. A., Borowsky, A. D., Besselsen, D. G., Thomson, C. A., Pandey, R., and Thompson, P. A. Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice. Carcinogenesis 2010;31(9):1642-1649. View abstract.

Foote, M. R., Giesy, S. L., Bernal-Santos, G., Bauman, D. E., and Boisclair, Y. R. t10,c12-CLA decreases adiposity in peripubertal mice without dose-related detrimental effects on mammary development, inflammation status and metabolism. Am.J Physiol Regul.Integr.Comp Physiol 9-15-2010; View abstract.

Forti, E. and Birk, R. Z. Conjugated linoleic acid down-regulates expression of resistin and adiponectin in fully differentiated 3T3-F442A cells. Genes Nutr 2007;2(1):119-120. View abstract.

Fostok, S. F., Ezzeddine, R. A., Homaidan, F. R., Al Saghir, J. A., Salloum, R. G., Saliba, N. A., and Talhouk, R. S. Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus. BMC.Complement Altern.Med 2009;9:44. View abstract.

Fremann, D., Linseisen, J., and Wolfram, G. Dietary conjugated linoleic acid (CLA) intake assessment and possible biomarkers of CLA intake in young women. Public Health Nutr 2002;5(1):73-80. View abstract.

Fuentes, M. C., Calsamiglia, S., Cardozo, P. W., and Vlaeminck, B. Effect of pH and level of concentrate in the diet on the production of biohydrogenation intermediates in a dual-flow continuous culture. J Dairy Sci 2009;92(9):4456-4466. View abstract.

福田康夫年代,录像,Y。,Chikayama, Ohno H E。, Hino, T., and Kikuchi, J. Evaluation and characterization of bacterial metabolic dynamics with a novel profiling technique, real-time metabolotyping. PLoS.One. 2009;4(3):e4893. View abstract.

Fukuda, S., Suzuki, Y., Komori, T., Kawamura, K., Asanuma, N., and Hino, T. Purification and gene sequencing of conjugated linoleic acid reductase from a gastrointestinal bacterium, Butyrivibrio fibrisolvens. J Appl.Microbiol. 2007;103(2):365-371. View abstract.

Futakuchi, M., Cheng, J. L., Hirose, M., Kimoto, N., Cho, Y. M., Iwata, T., Kasai, M., Tokudome, S., and Shirai, T. Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Cancer Lett. 4-25-2002;178(2):131-139. View abstract.

Gammill, W., Proctor, A., and Jain, V. Comparative study of high-linoleic acid vegetable oils for the production of conjugated linoleic acid. J Agric.Food Chem. 3-10-2010;58(5):2952-2957. View abstract.

Gangidi, R. R. and Proctor, A. Photochemical production of conjugated linoleic acid from soybean oil. Lipids 2004;39(6):577-582. View abstract.

Garcia-Fernandez, M., Gutierrez-Gil, B., Garcia-Gamez, E., Sanchez, J. P., and Arranz, J. J. Detection of quantitative trait loci affecting the milk fatty acid profile on sheep chromosome 22: role of the stearoyl-CoA desaturase gene in Spanish Churra sheep. J Dairy Sci 2010;93(1):348-357. View abstract.

Garcia-Martinez, M. C. and Marquez-Ruiz, G. Lipid oxidation in functional dairy products. Current Nutrition & Food Science 2009;5(3):209-216.

Garnsworthy, P. C., Feng, S., Lock, A. L., and Royal, M. D. Short communication: heritability of milk fatty acid composition and stearoyl-CoA desaturase indices in dairy cows. J Dairy Sci 2010;93(4):1743-1748. View abstract.

Gaullier, J. M., Halse, J., Hoivik, H. O., Hoye, K., Syvertsen, C., Nurminiemi, M., Hassfeld, C., Einerhand, A., O'Shea, M., and Gudmundsen, O. Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese. Br.J Nutr 2007;97(3):550-560. View abstract.

Gaullier, J. M., Halse, J., Hoye, K., Kristiansen, K., Fagertun, H., Vik, H., and Gudmundsen, O. Supplementation with conjugated linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humans. J Nutr 2005;135(4):778-784. View abstract.

Gervais, R. and Chouinard, P. Y. Effects of intravenous infusion of conjugated diene 18:3 isomers on milk fat synthesis in lactating dairy cows. J Dairy Sci 2008;91(9):3568-3578. View abstract.

Gervais, R., McFadden, J. W., Lengi, A. J., Corl, B. A., and Chouinard, P. Y. Effects of intravenous infusion of trans-10, cis-12 18:2 on mammary lipid metabolism in lactating dairy cows. J Dairy Sci 2009;92(10):5167-5177. View abstract.

Gillis, M. H., Duckett, S. K., and Sackmann, J. R. Effects of supplemental rumen-protected conjugated linoleic acid or corn oil on lipid content and palatability in beef cattle. J Anim Sci 2007;85(6):1504-1510. View abstract.

Glasser, F., Ferlay, A., and Chilliard, Y. Oilseed lipid supplements and fatty acid composition of cow milk: a meta-analysis. J Dairy Sci 2008;91(12):4687-4703. View abstract.

Goedecke, J. H., Rae, D. E., Smuts, C. M., Lambert, E. V., and O'Shea, M. Conjugated linoleic acid isomers, t10c12 and c9t11, are differentially incorporated into adipose tissue and skeletal muscle in humans. Lipids 2009;44(11):983-988. View abstract.

Goli, S. A. H. The Production of an Experimental Table Margarine Enriched with Conjugated Linoleic Acid (CLA): Physical Properties. JAOCS: Journal of the American Oil Chemists' Society 2009;85(5):453-458.

Gomez-Cortes, P., Bach, A., Luna, P., Juarez, M., and De la Fuente, M. A. Effects of extruded linseed supplementation on n-3 fatty acids and conjugated linoleic acid in milk and cheese from ewes. J Dairy Sci 2009;92(9):4122-4134. View abstract.

Gomez-Cortes, P., Frutos, P., Mantecon, A. R., Juarez, M., De la Fuente, M. A., and Hervas, G. Addition of olive oil to dairy ewe diets: effect on milk fatty acid profile and animal performance. J Dairy Sci 2008;91(8):3119-3127. View abstract.

Gomez-Cortes, P., Frutos, P., Mantecon, A. R., Juarez, M., De la Fuente, M. A., and Hervas, G. Effect of supplementation of grazing dairy ewes with a cereal concentrate on animal performance and milk fatty acid profile. J Dairy Sci 2009;92(8):3964-3972. View abstract.

Gomez-Cortes, P., Frutos, P., Mantecon, A. R., Juarez, M., De la Fuente, M. A., and Hervas, G. Milk production, conjugated linoleic acid content, and in vitro ruminal fermentation in response to high levels of soybean oil in dairy ewe diet. J Dairy Sci 2008;91(4):1560-1569. View abstract.

Gorissen, L., Raes, K., Weckx, S., Dannenberger, D., Leroy, F., De Vuyst, L., and De Smet, S. Production of conjugated linoleic acid and conjugated linolenic acid isomers by Bifidobacterium species. Appl.Microbiol.Biotechnol. 2010;87(6):2257-2266. View abstract.

Goua, M., Mulgrew, S., Frank, J., Rees, D., Sneddon, A. A., and Wahle, K. W. Regulation of adhesion molecule expression in human endothelial and smooth muscle cells by omega-3 fatty acids and conjugated linoleic acids: involvement of the transcription factor NF-kappaB? Prostaglandins Leukot.Essent.Fatty Acids 2008;78(1):33-43. View abstract.

Gross, S., Iannone, R., Xiao, S., and Bertram, A. K. Reactive uptake studies of NO3 and N2O5 on alkenoic acid, alkanoate, and polyalcohol substrates to probe nighttime aerosol chemistry. Phys.Chem.Chem.Phys. 9-28-2009;11(36):7792-7803. View abstract.

Grossmann, M. E., Mizuno, N. K., Dammen, M. L., Schuster, T., Ray, A., and Cleary, M. P. Eleostearic Acid inhibits breast cancer proliferation by means of an oxidation-dependent mechanism. Cancer Prev.Res (Phila) 2009;2(10):879-886. View abstract.

Gudbrandsen, O. A., Rodriguez, E., Wergedahl, H., Mork, S., Reseland, J. E., Skorve, J., Palou, A., and Berge, R. K. Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. Br.J Nutr 2009;102(6):803-815. View abstract.

Guillen, N., Navarro, M. A., Arnal, C., Noone, E., Arbones-Mainar, J. M., Acin, S., Surra, J. C., Muniesa, P., Roche, H. M., and Osada, J. Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver. Physiol Genomics 5-13-2009;37(3):187-198. View abstract.

Ha, Y. L., Grimm, N. K., and Pariza, M. W. Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid. Carcinogenesis 1987;8(12):1881-1887. View abstract.

Halade, G. V., Rahman, M. M., and Fernandes, G. Differential effects of conjugated linoleic acid isomers in insulin-resistant female C57Bl/6J mice. J Nutr Biochem. 2010;21(4):332-337. View abstract.

Halade, G. V., Rahman, M. M., and Fernandes, G. Effect of CLA isomers and their mixture on aging C57Bl/6J mice. Eur J Nutr 2009;48(7):409-418. View abstract.

Halade, G. V., Rahman, M. M., Williams, P. J., and Fernandes, G. Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J mice. J Nutr Biochem. 7-23-2010; View abstract.

Hamam, F. and Shahidi, F. Acidolysis of tristearin with selected long-chain fatty acids. J Agric.Food Chem. 3-7-2007;55(5):1955-1960. View abstract.

Hamam, F. and Shahidi, F. Enzymatic Incorporation of Selected Long-Chain Fatty Acids into Triolein. JAOCS: Journal of the American Oil Chemists' Society 2007;84(6):533-541.

Hand, K. V., Bruen, C. M., O'Halloran, F., Giblin, L., and Green, B. D. Acute and chronic effects of dietary fatty acids on cholecystokinin expression, storage and secretion in enteroendocrine STC-1 cells. Mol.Nutr Food Res 2010;54 Suppl 1:S93-S103. View abstract.

Hargrave, K. M., Meyer, B. J., Li, C., Azain, M. J., Baile, C. A., and Miner, J. L. Influence of dietary conjugated linoleic Acid and fat source on body fat and apoptosis in mice. Obes Res 2004;12(9):1435-1444. View abstract.

Hargrave-Barnes, K. M., Azain, M. J., and Miner, J. L. Conjugated linoleic acid-induced fat loss dependence on Delta6-desaturase or cyclooxygenase. Obesity.(Silver.Spring) 2008;16(10):2245-2252. View abstract.

Harris, M. A., Hansen, R. A., Vidsudhiphan, P., Koslo, J. L., Thomas, J. B., Watkins, B. A., and Allen, K. G. Effects of conjugated linoleic acids and docosahexaenoic acid on rat liver and reproductive tissue fatty acids, prostaglandins and matrix metalloproteinase production. Prostaglandins Leukot.Essent.Fatty Acids 2001;65(1):23-29. View abstract.

Harvatine, K. J., Perfield, J. W., and Bauman, D. E. Expression of enzymes and key regulators of lipid synthesis is upregulated in adipose tissue during CLA-induced milk fat depression in dairy cows. J Nutr 2009;139(5):849-854. View abstract.

Hashem, M. A., Jun, K. Y., Lee, E., Lim, S., Choo, H. Y., and Kwon, Y. A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds. Mol.Cells 12-31-2008;26(6):625-630. View abstract.

Haug, A., Sjogren, P., Holland, N., Muller, H., Kjos, N. P., Taugbol, O., Fjerdingby, N., Biong, A. S., Selmer-Olsen, E., and Harstad, O. M. Effects of butter naturally enriched with conjugated linoleic acid and vaccenic acid on blood lipids and LDL particle size in growing pigs. Lipids Health Dis. 2008;7:31. View abstract.

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Hayek, M. G., Han, S. N., Wu, D., Watkins, B. A., Meydani, M., Dorsey, J. L., Smith, D. E., and Meydani, S. N. Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. J Nutr 1999;129(1):32-38. View abstract.

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Heck, J. M., van Valenberg, H. J., Dijkstra, J., and van Hooijdonk, A. C. Seasonal variation in the Dutch bovine raw milk composition. J Dairy Sci 2009;92(10):4745-4755. View abstract.

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Hernandez, E. R., Jacome, M. M., Lee, R. G., Nakano, T., Ozimek, L., and Guzman, I. V. [High conjugated linoleic acid (CLA) content in milk and dairy products using a dietary supplementation of sunflower seed in cows. Thrombogenic/atherogenic risk issues]. Arch.Latinoam.Nutr 2007;57(2):173-178. View abstract.

Hernandez-Diaz, G., Alexander-Aguilera, A., Arzaba-Villalba, A., Soto-Rodriguez, I., and Garcia, H. S. Effect of conjugated linoleic acid on body fat, tumor necrosis factor alpha and resistin secretion in spontaneously hypertensive rats. Prostaglandins Leukot.Essent.Fatty Acids 2010;82(2-3):105-109. View abstract.

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Herrera, J. A., Arevalo-Herrera, M., Shahabuddin, A. K., Ersheng, G., Herrera, S., Garcia, R. G., and Lopez-Jaramillo, P. Calcium and conjugated linoleic acid reduces pregnancy-induced hypertension and decreases intracellular calcium in lymphocytes. Am.J.Hypertens. 2006;19(4):381-387. View abstract.

Herrera, J. A., Shahabuddin, A. K., Ersheng, G., Wei, Y., Garcia, R. G., and Lopez-Jaramillo, P. Calcium plus linoleic acid therapy for pregnancy-induced hypertension. Int J Gynaecol Obstet 2005;91(3):221-227. View abstract.

Herrmann, J., Rubin, D., Hasler, R., Helwig, U., Pfeuffer, M., Auinger, A., Laue, C., Winkler, P., Schreiber, S., Bell, D., and Schrezenmeir, J. Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARgamma2 P12A polymorphism: a double blind, randomized, controlled cross-over study. Lipids Health Dis. 2009;8:35. View abstract.

Hilakivi-Clarke, L. Nutritional modulation of terminal end buds: its relevance to breast cancer prevention. Curr Cancer Drug Targets. 2007;7(5):465-474. View abstract.

Hirao, A., Yamasaki, M., Chujo, H., Koyanagi, N., Kanouchi, H., Yasuda, S., Matsuo, A., Nishida, E., Rikimaru, T., Tsujita, E., Shimada, M., Maehara, Y., Tachibana, H., and Yamada, K. Effect of dietary conjugated linoleic acid on liver regeneration after a partial hepatectomy in rats. J Nutr Sci Vitaminol.(Tokyo) 2004;50(1):9-12. View abstract.

Hoffmann, K., Blaudszun, J., Brunken, C., Tauber, R., Hopker, W. W., and Steinhart, H. Distribution of conjugated linoleic acid in total and subcellular fractions from normal and cancerous parts of human testes. Mol.Nutr Food Res 2005;49(8):756-762. View abstract.

Hommelberg, P. P., Plat, J., Remels, A. H., van Essen, A. L., Kelders, M. C., Mensink, R. P., Schols, A. M., and Langen, R. C. Trans-10, cis-12 conjugated linoleic acid inhibits skeletal muscle differentiation and GLUT4 expression independently from NF-kappaB activation. Mol.Nutr Food Res 6-21-2010; View abstract.

Hontecillas, R., Wannemeulher, M. J., Zimmerman, D. R., Hutto, D. L., Wilson, J. H., Ahn, D. U., and Bassaganya-Riera, J. Nutritional regulation of porcine bacterial-induced colitis by conjugated linoleic acid. J Nutr 2002;132(7):2019-2027. View abstract.

House, R. L., Cassady, J. P., Eisen, E. J., McIntosh, M. K., and Odle, J. Conjugated linoleic acid evokes de-lipidation through the regulation of genes controlling lipid metabolism in adipose and liver tissue. Obes.Rev 2005;6(3):247-258. View abstract.

Houseknecht, K. L., Vanden Heuvel, J. P., Moya-Camarena, S. Y., Portocarrero, C. P., Peck, L. W., Nickel, K. P., and Belury, M. A. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem.Biophys.Res Commun. 3-27-1998;244(3):678-682. View abstract.

Hsu, Y. C., Meng, X., Ou, L., and Ip, M. M. Activation of the AMP-activated protein kinase-p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells. Cell Signal. 2010;22(4):590-599. View abstract.

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Hubbard, N. E., Lim, D., and Erickson, K. L. Conjugated linoleic acid alters matrix metalloproteinases of metastatic mouse mammary tumor cells. J Nutr 2007;137(6):1423-1429. View abstract.

Hubbard, N. E., Lim, D., Summers, L., and Erickson, K. L. Reduction of murine mammary tumor metastasis by conjugated linoleic acid. Cancer Lett. 3-13-2000;150(1):93-100. View abstract.

Hue, J. J., Lee, K. N., Jeong, J. H., Lee, S. H., Lee, Y. H., Jeong, S. W., Nam, S. Y., Yun, Y. W., and Lee, B. J. Anti-obesity activity of diglyceride containing conjugated linoleic acid in C57BL/6J ob/ob mice. J Vet.Sci 2009;10(3):189-195. View abstract.

Huebner, S. M., Campbell, J. P., Butz, D. E., Fulmer, T. G., Gendron-Fitzpatrick, A., and Cook, M. E. Individual isomers of conjugated linoleic acid reduce inflammation associated with established collagen-induced arthritis in DBA/1 mice. J Nutr 2010;140(8):1454-1461. View abstract.

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Huot, P. S., Sarkar, B., and Ma, D. W. Conjugated linoleic acid alters caveolae phospholipid fatty acid composition and decreases caveolin-1 expression in MCF-7 breast cancer cells. Nutr Res 2010;30(3):179-185. View abstract.

Hur, S. J. and Park, Y. Effect of conjugated linoleic acid on bone formation and rheumatoid arthritis. Eur J Pharmacol. 7-30-2007;568(1-3):16-24. View abstract.

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Hurtaud, C. and Peyraud, J. L. Effects of feeding camelina (seeds or meal) on milk fatty acid composition and butter spreadability. J Dairy Sci 2007;90(11):5134-5145. View abstract.

Huws, S. A., Kim, E. J., Kingston-Smith, A. H., Lee, M. R., Muetzel, S. M., Cookson, A. R., Newbold, C. J., Wallace, R. J., and Scollan, N. D. Rumen protozoa are rich in polyunsaturated fatty acids due to the ingestion of chloroplasts. FEMS Microbiol.Ecol. 2009;69(3):461-471. View abstract.

Hwang, D. M., Kundu, J. K., Shin, J. W., Lee, J. C., Lee, H. J., and Surh, Y. J. cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt. Carcinogenesis 2007;28(2):363-371. View abstract.

Hwang, Y. H. and Kang, K. J. Conjugated linoleic acid reduces adipose depots without reduction of stearoyl coenzyme A desaturase 1 gene expression. Ann.Nutr Metab 2007;51(2):126-133. View abstract.

Iannone, A., Petroni, A., Murru, E., Cordeddu, L., Carta, G., Melis, M. P., Bergamini, S., Casa, L. D., Cappiello, L., Carissimi, R., O'Shea, M., Bell, D., De Santis, E., and Banni, S. Impairment of 8-iso-PGF(2ALPHA) isoprostane metabolism by dietary conjugated linoleic acid (CLA). Prostaglandins Leukot.Essent.Fatty Acids 2009;80(5-6):279-287. View abstract.

Iassonova, D., Hammond, E. G., and Beattie, S. E. Oxidative Stability of Polyunsaturated Triacylglycerols Encapsulated in Oleaginous Yeast. JAOCS: Journal of the American Oil Chemists' Society 2008;85(8):711-716.

Igarashi, M. and Miyazawa, T. The growth inhibitory effect of conjugated linoleic acid on a human hepatoma cell line, HepG2, is induced by a change in fatty acid metabolism, but not the facilitation of lipid peroxidation in the cells. Biochim.Biophys Acta 2-26-2001;1530(2-3):162-171. View abstract.

Ingelsson, E. and Riserus, U. Effects of trans10cis12CLA-induced insulin resistance on retinol-binding protein 4 concentrations in abdominally obese men. Diabetes Res Clin.Pract. 2008;82(3):e23-e24. View abstract.

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Inouye, M., Hashimoto, H., Mio, T., and Sumino, K. Levels of lipid peroxidation product and glycated hemoglobin A1c in the erythrocytes of diabetic patients. Clin Chim.Acta 8-28-1998;276(2):163-172. View abstract.

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Ip, C., Briggs, S. P., Haegele, A. D., Thompson, H. J., Storkson, J., and Scimeca, J. A. The efficacy of conjugated linoleic acid in mammary cancer prevention is independent of the level or type of fat in the diet. Carcinogenesis 1996;17(5):1045-1050. View abstract.

Ip, C., Dong, Y., Thompson, H. J., Bauman, D. E., and Ip, M. M. Control of rat mammary epithelium proliferation by conjugated linoleic acid. Nutr Cancer 2001;39(2):233-238. View abstract.

Ip, C., Scimeca, J. A., and Thompson, H. Effect of timing and duration of dietary conjugated linoleic acid on mammary cancer prevention. Nutr Cancer 1995;24(3):241-247. View abstract.

Ip, M. M., Masso-Welch, P. A., and Ip, C. Prevention of mammary cancer with conjugated linoleic acid: role of the stroma and the epithelium. J Mammary.Gland.Biol Neoplasia. 2003;8(1):103-118. View abstract.

Ip, M. M., Masso-Welch, P. A., Shoemaker, S. F., Shea-Eaton, W. K., and Ip, C. Conjugated linoleic acid inhibits proliferation and induces apoptosis of normal rat mammary epithelial cells in primary culture. Exp Cell Res 7-10-1999;250(1):22-34. View abstract.

Ip, M. M., McGee, S. O., Masso-Welch, P. A., Ip, C., Meng, X., Ou, L., and Shoemaker, S. F. The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium. Carcinogenesis 2007;28(6):1269-1276. View abstract.

Islam, M. A., Kim, Y. S., Jang, W. J., Lee, S. M., Kim, H. G., Kim, S. Y., Kim, J. O., and Ha, Y. L. A mixture of trans, trans conjugated linoleic acid induces apoptosis in MCF-7 human breast cancer cells with reciprocal expression of Bax and Bcl-2. J Agric.Food Chem. 7-23-2008;56(14):5970-5976. View abstract.

Islam, M. A., Kim, Y. S., Oh, T. W., Kim, G. S., Won, C. K., Kim, H. G., Choi, M. S., Kim, J. O., and Ha, Y. L. Superior anticarcinogenic activity of trans,trans-conjugated linoleic acid in N-methyl-N-nitrosourea-induced rat mammary tumorigenesis. J Agric.Food Chem. 5-12-2010;58(9):5670-5678. View abstract.

Iwata, T., Kamegai, T., Yamauchi-Sato, Y., Ogawa, A., Kasai, M., Aoyama, T., and Kondo, K. Safety of dietary conjugated linoleic acid (CLA) in a 12-weeks trial in healthy overweight Japanese male volunteers. J Oleo.Sci 2007;56(10):517-525. View abstract.

Jacome-Sosa, M. M., Lu, J., Wang, Y., Ruth, M. R., Wright, D. C., Reaney, M. J., Shen, J., Field, C. J., Vine, D. F., and Proctor, S. D. Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp rat. Nutr Metab (Lond) 2010;7:60. View abstract.

Jain, V. P. and Proctor, A. Kinetics of photoirradiation-induced synthesis of soy oil-conjugated linoleic acid isomers. J Agric.Food Chem. 2-7-2007;55(3):889-894. View abstract.

Jain, V. P. and Proctor, A. Production of conjugated linoleic acid-rich potato chips. J Food Sci 2007;72(1):S075-S078. View abstract.

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Jalc, D., Varadyova, Z., and Laukova, A. Effect of inoculated corn silage enriched with sunflower oil on rumen fermentation and lipid metabolism in an artificial rumen (RUSITEC). J Sci Food Agric. 1-15-2010;90(1):78-84. View abstract.

Janz, J. A., Morel, P. C., Purchas, R. W., Corrigan, V. K., Cumarasamy, S., Wilkinson, B. H., and Hendriks, W. H. The influence of diets supplemented with conjugated linoleic acid, selenium, and vitamin E, with or without animal protein, on the quality of pork from female pigs. J Anim Sci 2008;86(6):1402-1409. View abstract.

Jaudszus, A., Krokowski, M., Mockel, P., Darcan, Y., Avagyan, A., Matricardi, P., Jahreis, G., and Hamelmann, E. Cis-9,trans-11-conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARgamma-related mechanism in mice. J Nutr 2008;138(7):1336-1342. View abstract.

Javadi, M., Everts, H., Hovenier, R., Kocsis, S., Lankhorst, A. E., Lemmens, A. G., Schonewille, J. T., Terpstra, A. H., and Beynen, A. C. The effect of six different C18 fatty acids on body fat and energy metabolism in mice. Br J Nutr 2004;92(3):391-399. View abstract.

Javadi, M., Geelen, M. J., Everts, H., Hovenier, R., Javadi, S., Kappert, H., and Beynen, A. C. Effect of dietary conjugated linoleic acid on body composition and energy balance in broiler chickens. Br.J Nutr 2007;98(6):1152-1158. View abstract.

Jenkins, T. C., Wallace, R. J., Moate, P. J., and Mosley, E. E. Board-invited review: Recent advances in biohydrogenation of unsaturated fatty acids within the rumen microbial ecosystem. J Anim Sci 2008;86(2):397-412. View abstract.

Jenko, K. J. and Vanderhoek, J. Y. Conjugated linoleic acids and CLA-containing phospholipids inhibit NO formation in aortic endothelial cells. Lipids 2008;43(4):335-342. View abstract.

Jensen, R. G. and Lammi-Keefe, C. The anticarcinogenic conjugated fatty acid c9, t11-c18:2, or rumenic acid, in human milk: amounts and effects. Adv Exp Med Biol 2001;501:153-156. View abstract.

Jeon, S. M., Kim, H. J., Woo, M. N., Lee, M. K., Shin, Y. C., Park, Y. B., and Choi, M. S. Fucoxanthin-rich seaweed extract suppresses body weight gain and improves lipid metabolism in high-fat-fed C57BL/6J mice. Biotechnol.J 2010;5(9):961-969. View abstract.

Jeukendrup, A. E. and Aldred, S. Fat supplementation, health, and endurance performance. Nutrition 2004;20(7-8):678-688. View abstract.

Jiang, J., Zhao, M. J., Lin, F., Yang, L., and Zhou, X. Q. Effect of conjugated linoleic acid on Cyprinus carpio var. Jian regarding growth, immunity, and disease resistance to Aeromonas hydrophila. Lipids 2010;45(6):531-536. View abstract.

Jiang, T., Busboom, J. R., Nelson, M. L., O'Fallon, J., Ringkob, T. P., Joos, D., and Piper, K. Effect of sampling fat location and cooking on fatty acid composition of beef steaks. Meat.Sci 2010;84(1):86-92. View abstract.

Jiang, Z. Y., Zhong, W. J., Zheng, C. T., Lin, Y. C., Yang, L., and Jiang, S. Q. Conjugated linoleic acid differentially regulates fat deposition in backfat and longissimus muscle of finishing pigs. J Anim Sci 2010;88(5):1694-1705. View abstract.

Jiang, Z., Michal, J. J., Tobey, D. J., Daniels, T. F., Rule, D. C., and Macneil, M. D. Significant associations of stearoyl-CoA desaturase (SCD1) gene with fat deposition and composition in skeletal muscle. Int J Biol.Sci 2008;4(6):345-351. View abstract.

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Jones, E. L., Shingfield, K. J., Kohen, C., Jones, A. K., Lupoli, B., Grandison, A. S., Beever, D. E., Williams, C. M., Calder, P. C., and Yaqoob, P. Chemical, physical, and sensory properties of dairy products enriched with conjugated linoleic acid. J Dairy Sci 2005;88(8):2923-2937. View abstract.

Jorgensen, H., Hansen, C. H., Mu, H., and Jakobsen, K. Protein and energy metabolism of young male Wistar rats fed conjugated linoleic acid as structured triacylglycerol. Arch.Anim Nutr 2010;64(4):322-336. View abstract.

Jose, A. A., Gama, M. A., and Lanna, D. D. Effects of trans-10, cis-12 conjugated linoleic acid on gene expression and lipid metabolism of adipose tissue of growing pigs. Genet.Mol.Res 2008;7(2):284-294. View abstract.

Joseph, S. V., Liu, X., Wakefield, A., Chouinard, P. Y., Aukema, H., Jones, P. J., and Jacques, H. Trans-8, cis-10+ cis-9, trans-11-conjugated linoleic acid mixture alters body composition in Syrian golden hamsters fed a hypercholesterolaemic diet. Br.J Nutr 7-8-2010;1-7. View abstract.

Joseph, S. V., Miller, J. R., McLeod, R. S., and Jacques, H. Effect of trans8, cis10+cis9, trans11 conjugated linoleic acid mixture on lipid metabolism in 3T3-L1 cells. Lipids 2009;44(7):613-620. View abstract.

Josyula, S. and Schut, H. A. Effects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 rats. Nutr Cancer 1998;32(3):139-145. View abstract.

Jourdan, T., Djaouti, L., Demizieux, L., Gresti, J., Verges, B., and Degrace, P. Liver carbohydrate and lipid metabolism of insulin-deficient mice is altered by trans-10, cis-12 conjugated linoleic acid. J Nutr 2009;139(10):1901-1907. View abstract.

Juarez, M., Horcada, A., Alcalde, M. J., Valera, M., Polvillo, O., and Molina, A. Meat and fat quality of unweaned lambs as affected by slaughter weight and breed. Meat.Sci 6-17-2009; View abstract.

Jung, J. I., Cho, H. J., Kim, J., Kwon, D. Y., and Park, J. H. trans-10,cis-12 conjugated linoleic acid inhibits insulin-like growth factor-I receptor signaling in TSU-Pr1 human bladder cancer cells. J Med Food 2010;13(1):13-19. View abstract.

Jung, M. Y. and Jung, M. O. Identification of conjugated linoleic acids in hydrogenated soybean oil by silver ion-impregnated HPLC and gas chromatography-ion impacted mass spectrometry of their 4,4-dimethyloxazoline derivatives. J Agric.Food Chem 10-9-2002;50(21):6188-6193. View abstract.

Kadamne, J. V., Jain, V. P., Saleh, M., and Proctor, A. Measurement of conjugated linoleic acid (CLA) in CLA-rich soy oil by attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR). J Agric.Food Chem. 11-25-2009;57(22):10483-10488. View abstract.

Kadegowda, A. K., Bionaz, M., Piperova, L. S., Erdman, R. A., and Loor, J. J. Peroxisome proliferator-activated receptor-gamma activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents. J Dairy Sci 2009;92(9):4276-4289. View abstract.

Kadegowda, A. K., Bionaz, M., Thering, B., Piperova, L. S., Erdman, R. A., and Loor, J. J. Identification of internal control genes for quantitative polymerase chain reaction in mammary tissue of lactating cows receiving lipid supplements. J Dairy Sci 2009;92(5):2007-2019. View abstract.

Kadegowda, A. K., Connor, E. E., Teter, B. B., Sampugna, J., Delmonte, P., Piperova, L. S., and Erdman, R. A. Dietary trans fatty acid isomers differ in their effects on mammary lipid metabolism as well as lipogenic gene expression in lactating mice. J Nutr 2010;140(5):919-924. View abstract.

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Kadegowda, A. K., Piperova, L. S., Delmonte, P., and Erdman, R. A. Abomasal infusion of butterfat increases milk fat in lactating dairy cows. J Dairy Sci 2008;91(6):2370-2379. View abstract.

Kamlage, B., Hartmann, L., Gruhl, B., and Blaut, M. Intestinal microorganisms do not supply associated gnotobiotic rats with conjugated linoleic acid. J Nutr 1999;129(12):2212-2217. View abstract.

Kamlage, B., Hartmann, L., Gruhl, B., and Blaut, M. Linoleic acid conjugation by human intestinal microorganisms is inhibited by glucose and other substrates in vitro and in gnotobiotic rats. J Nutr 2000;130(8):2036-2039. View abstract.

Kamphuis, M. M., Lejeune, M. P., Saris, W. H., and Westerterp-Plantenga, M. S. The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects. Int J Obes Relat Metab Disord 2003;27(7):840-847. View abstract.

Kang, J. H. and Yang, M. P. In vitro evaluation of the effect of trans-10, cis-12 conjugated linoleic acid on phagocytosis by canine peripheral blood polymorphonuclear neutrophilic leukocytes exposed to methylprednisolone sodium succinate. Am.J Vet.Res 2008;69(4):494-500. View abstract.

Kang, J. H., Lee, G. S., Jeung, E. B., and Yang, M. P. Trans-10, cis-12 conjugated linoleic acid modulates phagocytic responses of canine peripheral blood polymorphonuclear neutrophilic leukocytes exposed to Clostridium difficile toxin B. Vet.Immunol.Immunopathol. 8-15-2009;130(3-4):178-186. View abstract.

Kang, J. H., Lee, G. S., Jeung, E. B., and Yang, M. P. Trans-10, cis-12-conjugated linoleic acid increases phagocytosis of porcine peripheral blood polymorphonuclear cells in vitro. Br.J Nutr 2007;97(1):117-125. View abstract.

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Karnati, S. K., Sylvester, J. T., Ribeiro, C. V., Gilligan, L. E., and Firkins, J. L. Investigating unsaturated fat, monensin, or bromoethanesulfonate in continuous cultures retaining ruminal protozoa. I. Fermentation, biohydrogenation, and microbial protein synthesis. J Dairy Sci 2009;92(8):3849-3860. View abstract.

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Kawahara, S., Takenoyama, S., Takuma, K., Muguruma, M., and Yamauchi, K. Effects of dietary supplementation with conjugated linoleic acid on fatty acid composition and lipid oxidation in chicken breast meat. Anim Sci J 2009;80(4):468-474. View abstract.

Kay, J. K., Mackle, T. R., Bauman, D. E., Thomson, N. A., and Baumgard, L. H. Effects of a supplement containing trans-10, cis-12 conjugated linoleic acid on bioenergetic and milk production parameters in grazing dairy cows offered ad libitum or restricted pasture. J Dairy Sci 2007;90(2):721-730. View abstract.

Keating, A. F., Zhao, F. Q., Finucane, K. A., Glimm, D. R., and Kennelly, J. J. Effect of conjugated linoleic acid on bovine mammary cell growth, apoptosis and stearoyl Co-A desaturase gene expression. Domest.Anim Endocrinol. 2008;34(3):284-292. View abstract.

Kelley, D. S. and Erickson, K. L. Modulation of body composition and immune cell functions by conjugated linoleic acid in humans and animal models: benefits vs. risks. Lipids 2003;38(4):377-386. View abstract.

Kelley, D. S., Bartolini, G. L., Newman, J. W., Vemuri, M., and Mackey, B. E. Fatty acid composition of liver, adipose tissue, spleen, and heart of mice fed diets containing t10, c12-, and c9, t11-conjugated linoleic acid. Prostaglandins Leukot.Essent.Fatty Acids 4-20-2006; View abstract.

Kelley, D. S., Taylor, P. C., Rudolph, I. L., Benito, P., Nelson, G. J., Mackey, B. E., and Erickson, K. L. Dietary conjugated linoleic acid did not alter immune status in young healthy women. Lipids 2000;35(10):1065-1071. View abstract.

Kelley, N. S., Hubbard, N. E., and Erickson, K. L. Conjugated linoleic acid isomers and cancer. J Nutr 2007;137(12):2599-2607. View abstract.

Kelly, O. and Cashman, K. D. The effect of conjugated linoleic acid on calcium absorption and bone metabolism and composition in adult ovariectomised rats. Prostaglandins Leukot.Essent.Fatty Acids 2004;71(5):295-301. View abstract.

Kelly, O., Cusack, S., Jewell, C., and Cashman, K. D. The effect of polyunsaturated fatty acids, including conjugated linoleic acid, on calcium absorption and bone metabolism and composition in young growing rats. Br J Nutr 2003;90(4):743-750. View abstract.

Kemp, M. Q., Jeffy, B. D., and Romagnolo, D. F. Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. J Nutr 2003;133(11):3670-3677. View abstract.

Kennedy, A., Chung, S., LaPoint, K., Fabiyi, O., and McIntosh, M. K. Trans-10, cis-12 conjugated linoleic acid antagonizes ligand-dependent PPARgamma activity in primary cultures of human adipocytes. J Nutr 2008;138(3):455-461. View abstract.

Kennedy, A., Martinez, K., Chung, S., LaPoint, K., Hopkins, R., Schmidt, S. F., Andersen, K., Mandrup, S., and McIntosh, M. Inflammation and insulin resistance induced by trans-10, cis-12 conjugated linoleic acid depend on intracellular calcium levels in primary cultures of human adipocytes. J Lipid Res 2010;51(7):1906-1917. View abstract.

Kennedy, A., Martinez, K., Schmidt, S., Mandrup, S., LaPoint, K., and McIntosh, M. Antiobesity mechanisms of action of conjugated linoleic acid. J Nutr Biochem. 2010;21(3):171-179. View abstract.

Ibeagha-Awemu, Kgwatalala, p . M。e . M。海耶斯,J。F., and Zhao, X. Single nucleotide polymorphisms in the open reading frame of the stearoyl-CoA desaturase gene and resulting genetic variants in Canadian Holstein and Jersey cows. DNA Seq. 2007;18(5):357-362. View abstract.

Ibeagha-Awemu, Kgwatalala, p . M。e . M。海耶斯,J。F., and Zhao, X. Stearoyl-CoA desaturase 1 3'UTR SNPs and their influence on milk fatty acid composition of Canadian Holstein cows. J Anim Breed.Genet. 2009;126(5):394-403. View abstract.

Kgwatalala, P. M., Ibeagha-Awemu, E. M., Mustafa, A. F., and Zhao, X. Influence of stearoyl-coenzyme A desaturase 1 genotype and stage of lactation on fatty acid composition of Canadian Jersey cows. J Dairy Sci 2009;92(3):1220-1228. View abstract.

Kgwatalala, P. M., Ibeagha-Awemu, E. M., Mustafa, A. F., and Zhao, X. Stearoyl-CoA desaturase 1 genotype and stage of lactation influences milk fatty acid composition of Canadian Holstein cows. Anim Genet. 2009;40(5):609-615. View abstract.

Khiaosa-Ard, R., Klevenhusen, F., Soliva, C. R., Kreuzer, M., and Leiber, F. Transfer of linoleic and linolenic acid from feed to milk in cows fed isoenergetic diets differing in proportion and origin of concentrates and roughages. J Dairy Res 2010;77(3):331-336. View abstract.

Khodaei, H., Chamani, M., Sadeghi, A., and Hejazi, H. Effects of conjugated linoleic acid (CLA) on hormones and factors involved in murine ovulation. Medical Journal of Reproduction & Infertility 2009;10(2):157.

Kilian, M., Mautsch, I., Gregor, J. I., Heinichen, D., Jacobi, C. A., Schimke, I., Guski, H., Muller, J. M., and Wenger, F. A. Influence of conjugated and conventional linoleic acid on tumor growth and lipid peroxidation in pancreatic adenocarcinoma in hamster. Prostaglandins Leukot.Essent.Fatty Acids 2003;69(1):67-72. View abstract.

Kilian, M., Mautsch, I., Gregor, J. I., Stahlknecht, P., Jacobi, C. A., Schimke, I., Guski, H., and Wenger, F. A. Influence of conjugated vs. conventional linoleic acid on liver metastasis and hepatic lipidperoxidation in BOP-induced pancreatic cancer in Syrian hamster. Prostaglandins Leukot.Essent.Fatty Acids 2002;67(4):223-228. View abstract.

Kim, E. J., Holthuizen, P. E., Park, H. S., Ha, Y. L., Jung, K. C., and Park, J. H. Trans-10,cis-12-conjugated linoleic acid inhibits Caco-2 colon cancer cell growth. Am J Physiol Gastrointest.Liver Physiol 2002;283(2):G357-G367. View abstract.

Kim, E. J., Jun, J. G., Park, H. S., Kim, S. M., Ha, Y. L., and Park, J. H. Conjugated linoleic acid (CLA) inhibits growth of Caco-2 colon cancer cells: possible mediation by oleamide. Anticancer Res 2002;22(4):2193-2197. View abstract.

Kim, E. J., Kang, I. J., Cho, H. J., Kim, W. K., Ha, Y. L., and Park, J. H. Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells. J Nutr 2003;133(8):2675-2681. View abstract.

Kim, H. K., Kim, S. R., Ahn, J. Y., Cho, I. J., Yoon, C. S., and Ha, T. Y. Dietary conjugated linoleic acid reduces lipid peroxidation by increasing oxidative stability in rats. J Nutr Sci Vitaminol.(Tokyo) 2005;51(1):8-15. View abstract.

Kim, J. H., Choi, N. J., Park, H. G., Kim, I. H., Lee, H. G., Song, M. K., Whang, K. Y., and Kim, Y. J. Utilization of oil by-product from the purification process of conjugated linoleic Acid as feeding supplements for the accumulation of conjugated linoleic acid in the egg yolk. Poult.Sci 2008;87(1):64-70. View abstract.

Kim, J. H., Hubbard, N. E., Ziboh, V., and Erickson, K. L. Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein. Biochim.Biophys Acta 10-1-2005;1736(3):244-250. View abstract.

Kim, J. H., Hubbard, N. E., Ziboh, V., and Erickson, K. L. Conjugated linoleic acid reduction of murine mammary tumor cell growth through 5-hydroxyeicosatetraenoic acid. Biochim.Biophys Acta 2-21-2005;1687(1-3):103-109. View abstract.

Kim, J. H., Hwangbo, J., Choi, N. J., Park, H. G., Yoon, D. H., Park, E. W., Lee, S. H., Park, B. K., and Kim, Y. J. Effect of dietary supplementation with conjugated linoleic acid, with oleic, linoleic, or linolenic acid, on egg quality characteristics and fat accumulation in the egg yolk. Poult.Sci 2007;86(6):1180-1186. View abstract.

Kim, J. H., Jeong, W. S., Kim, I. H., Kim, H. J., Kim, S. H., Kang, G. H., Lee, H. G., Yoon, H. G., Ham, H. J., and Kim, Y. J. Effect of an oil byproduct from conjugated linoleic acid (CLA) purification on CLA accumulation and lipogenic gene expression in broilers. J Agric.Food Chem. 3-25-2009;57(6):2397-2404. View abstract.

Kim, J. H., Kwon, O. J., Choi, N. J., Oh, S. J., Jeong, H. Y., Song, M. K., Jeong, I., and Kim, Y. J. Variations in conjugated linoleic acid (CLA) content of processed cheese by lactation time, feeding regimen, and ripening. J Agric.Food Chem. 4-22-2009;57(8):3235-3239. View abstract.

Kim, J. H., Park, H. G., Pan, J. H., Kim, S. H., Yoon, H. G., Bae, G. S., Lee, H., Eom, S. H., and Kim, Y. J. Dietary conjugated linoleic acid increases endurance capacity of mice during treadmill exercise. J Med Food 2010;13(5):1057-1060. View abstract.

Kim, J. M., Kim, J. S., Kim, Y. J., Oh, Y. K., Kim, I. Y., Chee, Y. J., Han, J. S., and Jung, H. C. Conjugated linoleic acids produced by Lactobacillus dissociates IKK-gamma and Hsp90 complex in Helicobacter pylori-infected gastric epithelial cells. Lab Invest 2008;88(5):541-552. View abstract.

Kim, K. H. and Park, H. S. Dietary supplementation of conjugated linoleic acid reduces colon tumor incidence in DMH-treated rats by increasing apoptosis with modulation of biomarkers. Nutrition 2003;19(9):772-777. View abstract.

Kim, Y. J., Lee, K. W., and Lee, H. J. Total antioxidant capacity of arginine-conjugated linoleic acid (CLA) complex. J.Agric.Food Chem. 2-11-2004;52(3):439-444. View abstract.

Kim, Y. S., Cerbo, R. M., Hah, C. K., Bahn, K. N., Kim, J. O., and Ha, Y. L. Growth inhibition of osteosarcoma cell MG-63 by a mixture of trans,trans conjugated linoleic acid isomers: possible mechanistic actions. J Food Sci 2008;73(1):T7-15. View abstract.

Kim, Y. S., Kim, S. J., Oh, T. W., Byeon, J. I., Kim, G. S., Min, D. B., Jang, J. S., and Ha, Y. L. Differential inhibitory effects of conjugated linoleic acid isomers on mouse forestomach neoplasia induced by benzo(a)pyrene. J Agric.Food Chem. 3-10-2010;58(5):3177-3183. View abstract.

Kimoto, N., Hirose, M., Futakuchi, M., Iwata, T., Kasai, M., and Shirai, T. Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats. Cancer Lett. 7-10-2001;168(1):15-21. View abstract.

Kinami, T., Horii, N., and Narayan, B. Occurrence of Conjugated Linolenic Acids in Purified Soybean Oil. JAOCS: Journal of the American Oil Chemists' Society 2007;84(1):23-29.

Kishino, S., Ogawa, J., Yokozeki, K., and Shimizu, S. Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production. Appl.Microbiol.Biotechnol. 2009;84(1):87-97. View abstract.

Kloss, R., Linscheid, J., Johnson, A., Lawson, B., Edwards, K., Linder, T., Stocker, K., Petitte, J., and Kern, M. Effects of conjugated linoleic acid supplementation on blood lipids and adiposity of rats fed diets rich in saturated versus unsaturated fat. Pharmacol.Res 2005;51(6):503-507. View abstract.

Konig, B., Spielmann, J., Haase, K., Brandsch, C., Kluge, H., Stangl, G. I., and Eder, K. Effects of fish oil and conjugated linoleic acids on expression of target genes of PPAR alpha and sterol regulatory element-binding proteins in the liver of laying hens. Br.J Nutr 2008;100(2):355-363. View abstract.

Koronowicz, A., Dulinska-Litewka, J., Pisulewski, P., and Laidler, P. [Effect of conjugated linoleic acid isomers on proliferation of mammary cancer cells]. Rocz.Panstw.Zakl.Hig. 2009;60(3):261-267. View abstract.

Kraft, J., Kramer, J. K., Schoene, F., Chambers, J. R., and Jahreis, G. Extensive analysis of long-chain polyunsaturated fatty acids, CLA, trans-18:1 isomers, and plasmalogenic lipids in different retail beef types. J Agric.Food Chem. 6-25-2008;56(12):4775-4782. View abstract.

Kramer, J. K., Cruz-Hernandez, C., Deng, Z., Zhou, J., Jahreis, G., and Dugan, M. E. Analysis of conjugated linoleic acid and trans 18:1 isomers in synthetic and animal products. Am J Clin Nutr 2004;79(6 Suppl):1137S-1145S. View abstract.

Kramer, J. K., Hernandez, M., Cruz-Hernandez, C., Kraft, J., and Dugan, M. E. Combining results of two GC separations partly achieves determination of all cis and trans 16:1, 18:1, 18:2 and 18:3 except CLA isomers of milk fat as demonstrated using Ag-ion SPE fractionation. Lipids 2008;43(3):259-273. View abstract.

Kramer, J. K., Sehat, N., Dugan, M. E., Mossoba, M. M., Yurawecz, M. P., Roach, J. A., Eulitz, K., Aalhus, J. L., Schaefer, A. L., and Ku, Y. Distributions of conjugated linoleic acid (CLA) isomers in tissue lipid classes of pigs fed a commercial CLA mixture determined by gas chromatography and silver ion-high-performance liquid chromatography. Lipids 1998;33(6):549-558. View abstract.

Kreider, R. B., Ferreira, M. P., Greenwood, M., Wilson, M., and Almada, A. L. Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers. J Strength.Cond.Res 2002;16(3):325-334. View abstract.

Kritchevsky, D. Antimutagenic and some other effects of conjugated linoleic acid. Br J Nutr 2000;83(5):459-465. View abstract.

Kritchevsky, D., Tepper, S. A., Wright, S., Tso, P., and Czarnecki, S. K. Influence of conjugated linoleic acid (CLA) on establishment and progression of atherosclerosis in rabbits. J Am Coll Nutr 2000;19(4):472S-477S. View abstract.

Kucuk, O., Hess, B. W., and Rule, D. C. Fatty acid compositions of mixed ruminal microbes isolated from sheep supplemented with soybean oil. Res Vet.Sci 2008;84(2):215-224. View abstract.

Kuhnt, K., Degen, C., and Jahreis, G. 2-Propanol in the mobile phase reduces the time of analysis of CLA isomers by silver ion-HPLC. J Chromatogr.B Analyt.Technol Biomed.Life Sci 1-1-2010;878(1):88-91. View abstract.

Kuhnt K,卡夫,J。,Moeckel, P,和Jahreis, G。Trans-11-18 : 1 is effectively Delta9-desaturated compared with trans-12-18 : 1 in humans. Br J Nutr 2006;95(4):752-761. View abstract.

Kung, F. C. and Yang, M. C. Effect of conjugated linoleic acid immobilization on the hemocompatibility of cellulose acetate membrane. Colloids Surf.B Biointerfaces. 1-15-2006;47(1):36-42. View abstract.

Kuniyasu, H. The Roles of Dietary PPARgamma Ligands for Metastasis in Colorectal Cancer. PPAR.Res 2008;2008:529720. View abstract.

Kuniyasu, H., Yoshida, K., Sasaki, T., Sasahira, T., Fujii, K., and Ohmori, H. Conjugated linoleic acid inhibits peritoneal metastasis in human gastrointestinal cancer cells. Int J Cancer 2-1-2006;118(3):571-576. View abstract.

Lai, C., Yin, J., Li, D., Zhao, L., and Chen, X. Effects of dietary conjugated linoleic acid supplementation on performance and immune function of weaned pigs. Arch Anim Nutr 2005;59(1):41-51. View abstract.

Lall, R. K., Proctor, A., Jain, V. P., and Lay, J. O. Conjugated linoleic acid-rich soy oil triacylglycerol identification. J Agric.Food Chem. 3-11-2009;57(5):1727-1734. View abstract.

Lam, C. K., Chen, J., Cao, Y., Yang, L., Wong, Y. M., Yeung, S. Y., Yao, X., Huang, Y., and Chen, Z. Y. Conjugated and non-conjugated octadecaenoic acids affect differently intestinal acyl coenzyme A: cholesterol acyltransferase activity. Atherosclerosis 2008;198(1):85-93. View abstract.

Lambert, E. V., Goedecke, J. H., Bluett, K., Heggie, K., Claassen, A., Rae, D. E., West, S., Dugas, J., Dugas, L., Meltzeri, S., Charlton, K., and Mohede, I. Conjugated linoleic acid versus high-oleic acid sunflower oil: effects on energy metabolism, glucose tolerance, blood lipids, appetite and body composition in regularly exercising individuals. Br.J Nutr 2007;97(5):1001-1011. View abstract.

Riethoven LaRosa, p C。,J . J。,H。夏,Y。, Zhou, Y., Chen, M., Miner, J., and Fromm, M. E. Trans-10, cis-12 conjugated linoleic acid activates the integrated stress response pathway in adipocytes. Physiol Genomics 11-14-2007;31(3):544-553. View abstract.

Larsen, A. E. and Crowe, T. C. Effects of conjugated linoleic acid on myogenic and inflammatory responses in a human primary muscle and tumor coculture model. Nutr Cancer 2009;61(5):687-695. View abstract.

Larsen, A. E., Cameron-Smith, D., and Crowe, T. C. Conjugated linoleic acid suppresses myogenic gene expression in a model of human muscle cell inflammation. J Nutr 2008;138(1):12-16. View abstract.

Larsen, M. K., Nielsen, J. H., Butler, G., Leifert, C., Slots, T., Kristiansen, G. H., and Gustafsson, A. H. Milk quality as affected by feeding regimens in a country with climatic variation. J Dairy Sci 2010;93(7):2863-2873. View abstract.

Larsen, S. T., Wiegand, B. R., Parrish, F. C., Jr., Swan, J. E., and Sparks, J. C. Dietary conjugated linoleic acid changes belly and bacon quality from pigs fed varied lipid sources. J Anim Sci 2009;87(1):285-295. View abstract.

Larsen, T. M., Toubro, S., and Astrup, A. Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: evidence from animal and human studies. J Lipid Res 2003;44(12):2234-2241. View abstract.

Larsen, T. M., Toubro, S., Gudmundsen, O., and Astrup, A. Conjugated linoleic acid supplementation for 1 y does not prevent weight or body fat regain. Am J Clin Nutr 2006;83(3):606-612. View abstract.

Larsson, S. C., Bergkvist, L., and Wolk, A. Conjugated linoleic acid intake and breast cancer risk in a prospective cohort of Swedish women. Am.J Clin.Nutr 2009;90(3):556-560. View abstract.

Lasa, A., Churruca, I., Simon, E., Fernandez-Quintela, A., Rodriguez, V. M., and Portillo, M. P. Trans-10, cis-12-conjugated linoleic acid does not increase body fat loss induced by energy restriction. Br.J Nutr 2008;100(6):1245-1250. View abstract.

Lasa, A., Churruca, I., Simon, E., Macarulla, M. T., Fernandez-Quintela, A., Rodriguez, V. M., and Portillo, M. P. Effects of high-fat high-sucrose feeding, energy restriction, and trans-10,cis-12 conjugated linoleic acid on visfatin and apelin in hamsters. J Am.Coll.Nutr 2009;28(6):627-635. View abstract.

拉萨、。西蒙E, Churruca, Fernandez-Quint,我。ela, A., Macarulla, M. T., Martinez, J. A., and Portillo, M. P. Effects of trans-10,cis-12 CLA on liver size and fatty acid oxidation under energy restriction conditions in hamsters. Nutrition 8-7-2010; View abstract.

拉萨、。西蒙E, Churruca, Fernandez-Quint,我。ela, A., Rodriguez, V. M., and Portillo, M. P. Adiposity and serum parameters in hamsters fed energy restricted diets supplemented or not with trans-10,cis-12 conjugated linoleic acid. J Physiol Biochem. 2007;63(4):297-304. View abstract.

Laso, N., Brugue, E., Vidal, J., Ros, E., Arnaiz, J. A., Carne, X., Vidal, S., Mas, S., Deulofeu, R., and Lafuente, A. Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components. Br.J Nutr 2007;98(4):860-867. View abstract.

Lau, D. S. and Archer, M. C. The 10t,12c isomer of conjugated linoleic acid inhibits fatty acid synthase expression and enzyme activity in human breast, colon, and prostate cancer cells. Nutr Cancer 2010;62(1):116-121. View abstract.

LeDoux, M., Laloux, L., Fontaine, J. J., Carpentier, Y. A., Chardigny, J. M., and Sebedio, J. L. Rumenic acid significantly reduces plasma levels of LDL and small dense LDL cholesterol in hamsters fed a cholesterol- and lipid-enriched semi-purified diet. Lipids 2007;42(2):135-141. View abstract.

Lee, J. H., Cho, K. H., Lee, K. T., and Kim, M. R. Antiatherogenic effects of structured lipid containing conjugated linoleic acid in C57BL/6J mice. J Agric.Food Chem 9-7-2005;53(18):7295-7301. View abstract.

Lee, J. H., Tachibana, H., Morinaga, Y., Fujimura, Y., and Yamada, K. Modulation of proliferation and differentiation of C2C12 skeletal muscle cells by fatty acids. Life Sci 3-27-2009;84(13-14):415-420. View abstract.

Lee, J. S., Song, Y. B., Lee, J. Y., Kim, M. K., Jun, S. J., and Lee, H. G. Optimization and oxidative stability of the microencapsulated conjugated linoleic acid. Int J Biol.Macromol. 11-1-2009;45(4):348-351. View abstract.

Lee, K. and Lee, Y. Production of c9,t11- and t10,c12-conjugated linoleic acids in humans by Lactobacillus rhamnosus PL60. J Microbiol.Biotechnol. 2009;19(12):1617-1619. View abstract.

Lee, K. N., Pariza, M. W., and Ntambi, J. M. Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression. Biochem.Biophys.Res Commun. 7-30-1998;248(3):817-821. View abstract.

Lee, K. W., Lee, H. J., Cho, H. Y., and Kim, Y. J. Role of the conjugated linoleic acid in the prevention of cancer. Crit Rev Food Sci Nutr 2005;45(2):135-144. View abstract.

Lee, M. R. and Tweed, J. K. Isomerisation of cis-9 trans-11 conjugated linoleic acid (CLA) to trans-9 trans-11 CLA during acidic methylation can be avoided by a rapid base catalysed methylation of milk fat. J Dairy Res 2008;75(3):354-356. View abstract.

Lee, M. R., Huws, S. A., Scollan, N. D., and Dewhurst, R. J. Effects of fatty acid oxidation products (green odor) on rumen bacterial populations and lipid metabolism in vitro. J Dairy Sci 2007;90(8):3874-3882. View abstract.

Lee, S. H., Yamaguchi, K., Kim, J. S., Eling, T. E., Safe, S., Park, Y., and Baek, S. J. Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner. Carcinogenesis 2006;27(5):972-981. View abstract.

Lee, Y. and Vanden Heuvel, J. P. Inhibition of macrophage adhesion activity by 9trans,11trans-conjugated linoleic acid. J Nutr Biochem. 2010;21(6):490-497. View abstract.

Lee, Y., Thompson, J. T., and Vanden Heuvel, J. P. 9E,11E-conjugated linoleic acid increases expression of the endogenous antiinflammatory factor, interleukin-1 receptor antagonist, in RAW 264.7 cells. J Nutr 2009;139(10):1861-1866. View abstract.

Lee, Y., Thompson, J. T., de Lera, A. R., and Vanden Heuvel, J. P. Isomer-specific effects of conjugated linoleic acid on gene expression in RAW 264.7. J Nutr Biochem. 2009;20(11):848-59, 859. View abstract.

Lengi, A. J. and Corl, B. A. Factors influencing the differentiation of bovine preadipocytes in vitro. J Anim Sci 2010;88(6):1999-2008. View abstract.

Lengi, A. J. and Corl, B. A. Identification and characterization of a novel bovine stearoyl-CoA desaturase isoform with homology to human SCD5. Lipids 2007;42(6):499-508. View abstract.

楞次,T. L. and Hamilton, W. R. Supplemental products used for weight loss. J Am Pharm Assoc (Wash.DC.) 2004;44(1):59-67. View abstract.

Leone, V. A., Stransky, D. L., Aydin, R., and Cook, M. E. Evidence for conjugated linoleic acid-induced embryonic mortality that is independent of egg storage conditions and changes in egg relative fatty acids. Poult.Sci 2009;88(9):1858-1868. View abstract.

Leone, V. A., Worzalla, S. P., and Cook, M. E. Body compositional changes and growth alteration in chicks from hens fed conjugated linoleic acid. Lipids 2009;44(5):437-447. View abstract.

Leone, V. A., Worzalla, S. P., and Cook, M. E. Evidence that maternal conjugated linoleic acid negatively affects lipid uptake in late-stage chick embryos resulting in increased embryonic mortality. Poult.Sci 2010;89(4):621-632. View abstract.

Leung, Y. H. and Liu, R. H. trans-10,cis-12-conjugated linoleic acid isomer exhibits stronger oxyradical scavenging capacity than cis-9,trans-11-conjugated linoleic acid isomer. J.Agric.Food Chem. 2000;48(11):5469-5475. View abstract.

Li, J. J., Huang, C. J., and Xie, D. Anti-obesity effects of conjugated linoleic acid, docosahexaenoic acid, and eicosapentaenoic acid. Mol.Nutr Food Res 2008;52(6):631-645. View abstract.

Li, Y., Diao, Q., and Meng, Q. The effect of steam-flaked and extruded full-fat soybeans on the concentration of conjugated linoleic acid in the milk fat of dairy cows. Archives of Animal Nutrition 2009;63(3):243-253.

Li, Y., Seifert, M. F., Ney, D. M., Grahn, M., Grant, A. L., Allen, K. G., and Watkins, B. A. Dietary conjugated linoleic acids alter serum IGF-I and IGF binding protein concentrations and reduce bone formation in rats fed (n-6) or (n-3) fatty acids. J Bone Miner.Res 1999;14(7):1153-1162. View abstract.

Li, Z., Tran, V. H., Duke, R. K., Ng, M. C., Yang, D., and Duke, C. C. Synthesis and biological activity of hydroxylated derivatives of linoleic acid and conjugated linoleic acids. Chem.Phys.Lipids 2009;158(1):39-45. View abstract.

Liang, S., Yang, D., and Zeng, X. [Nutrition redistributing efficacy and safety of conjugated linoleic acid]. Wei Sheng Yan.Jiu. 2007;36(4):523-525. View abstract.

Liao, C. H., Shaw, H. M., and Chao, P. M. Impairment of glucose metabolism in mice induced by dietary oxidized frying oil is different from that induced by conjugated linoleic acid. Nutrition 2008;24(7-8):744-752. View abstract.

Liavonchanka, A. and Feussner, I. Biochemistry of PUFA double bond isomerases producing conjugated linoleic acid. Chembiochem. 8-11-2008;9(12):1867-1872. View abstract.

Lin, Y., Schuurbiers, E., Van, der, V, and de Deckere, E. A. Conjugated linoleic acid isomers have differential effects on triglyceride secretion in Hep G2 cells. Biochim.Biophys Acta 8-29-2001;1533(1):38-46. View abstract.

Liu, F., Zhong, R. Q., and Wang, Z. W. Formulation of Conjugated Linoleic Acid Microemulsion Using Mixed Nonionic Surfactants. Journal of Dispersion Science and Technology 2010;31:715-721.

Liu, J., Chen, B., Liu, R., and Lu, G. [Inhibitory effect of conjugated linoleic acid on human gastric carcinoma cell line]. Wei Sheng Yan.Jiu. 1999;28(6):353-355. View abstract.

Purushotham Liu l F。,。,万德尔,A。,lury, M. A. Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice. Am.J Physiol Gastrointest.Liver Physiol 2007;292(6):G1671-G1682. View abstract.

Livisay, S. A., Zhou, S., Ip, C., and Decker, E. A. Impact of dietary conjugated linoleic acid on the oxidative stability of rat liver microsomes and skeletal muscle homogenates. J Agric.Food Chem 2000;48(9):4162-4167. View abstract.

Lock, A. L., Horne, C. A., Bauman, D. E., and Salter, A. M. Butter naturally enriched in conjugated linoleic acid and vaccenic acid alters tissue fatty acids and improves the plasma lipoprotein profile in cholesterol-fed hamsters. J Nutr 2005;135(8):1934-1939. View abstract.

Lock, A. L., Rovai, M., Gipson, T. A., de Veth, M. J., and Bauman, D. E. A conjugated linoleic acid supplement containing trans-10, cis-12 conjugated linoleic acid reduces milk fat synthesis in lactating goats. J Dairy Sci 2008;91(9):3291-3299. View abstract.

Loor, J. J., Lin, X., and Herbein, J. H. Dietary trans-vaccenic acid (trans11-18:1) increases concentration of cis9,transll-conjugated linoleic acid (rumenic acid) in tissues of lactating mice and suckling pups. Reprod Nutr Dev. 2002;42(2):85-99. View abstract.

Lopes, P. A., Martins, S. V., Pinho, M. S., Alfaia, C. M., Fontes, C. M., Rodrigues, P. O., Morais, G. S., Castro, M. F., Pinto, R., and Prates, J. A. Diet supplementation with the cis-9,trans-11 conjugated linoleic acid isomer affects the size of adipocytes in Wistar rats. Nutr Res 2008;28(7):480-486. View abstract.

Lucchi, L., Banni, S., Iannone, A., Melis, M. P., Carta, G., Murru, E., Cordeddu, L., Stipo, L., Uggeri, S., Gatti, V., Malaguti, V., and Albertazzi, A. Changes in conjugated linoleic acid and palmitoleic acid are correlated to retinol levels in chronic renal failure in both hemodialysis and conservative treatment patients. Artif.Organs 2005;29(5):413-418. View abstract.

Lucchi, L., Banni, S., Melis, M. P., Angioni, E., Carta, G., Casu, V., Rapana, R., Ciuffreda, A., Corongiu, F. P., and Albertazzi, A. Changes in conjugated linoleic acid and its metabolites in patients with chronic renal failure. Kidney Int 2000;58(4):1695-1702. View abstract.

Ludden, P. A., Kucuk, O., Rule, D. C., and Hess, B. W. Growth and carcass fatty acid composition of beef steers fed soybean oil for increasing duration before slaughter. Meat.Sci 1-14-2009; View abstract.

Luna, P., Bach, A., Juarez, M., and De la Fuente, M. A. Effect of a diet enriched in whole linseed and sunflower oil on goat milk fatty acid composition and conjugated linoleic acid isomer profile. J Dairy Sci 2008;91(1):20-28. View abstract.

Luna, P., Juarez, M., and De la Fuente, M. A. Gas chromatography and silver-ion high-performance liquid chromatography analysis of conjugated linoleic acid isomers in free fatty acid form using sulphuric acid in methanol as catalyst. J Chromatogr.A 9-12-2008;1204(1):110-113. View abstract.

Luongo, D., Bergamo, P., and Rossi, M. Effects of conjugated linoleic acid on growth and cytokine expression in Jurkat T cells. Immunol Lett 12-15-2003;90(2-3):195-201. View abstract.

Ma, D. W., Field, C. J., and Clandinin, M. T. An enriched mixture of trans-10,cis-12-CLA inhibits linoleic acid metabolism and PGE2 synthesis in MDA-MB-231 cells. Nutr Cancer 2002;44(2):203-212. View abstract.

Macouzet, M., Lee, B. H., and Robert, N. Genetic and structural comparison of linoleate isomerases from selected food-grade bacteria. J Appl.Microbiol. 9-2-2010; View abstract.

Macouzet, M., Lee, B. H., and Robert, N. Production of conjugated linoleic acid by probiotic Lactobacillus acidophilus La-5. J Appl.Microbiol. 2009;106(6):1886-1891. View abstract.

Macouzet, M., Robert, N., and Lee, B. H. Genetic and functional aspects of linoleate isomerase in Lactobacillus acidophilus. Appl.Microbiol.Biotechnol. 2010;87(5):1737-1742. View abstract.

MacRedmond, R., Singhera, G., Attridge, S., Bahzad, M., Fava, C., Lai, Y., Hallstrand, T. S., and Dorscheid, D. R. Conjugated linoleic acid improves airway hyper-reactivity in overweight mild asthmatics. Clin.Exp.Allergy 2010;40(7):1071-1078. View abstract.

Maggiora, M., Bologna, M., Ceru, M. P., Possati, L., Angelucci, A., Cimini, A., Miglietta, A., Bozzo, F., Margiotta, C., Muzio, G., and Canuto, R. A. An overview of the effect of linoleic and conjugated-linoleic acids on the growth of several human tumor cell lines. Int J Cancer 12-20-2004;112(6):909-919. View abstract.

Majumder, B., Wahle, K. W., Moir, S., Schofield, A., Choe, S. N., Farquharson, A., Grant, I., and Heys, S. D. Conjugated linoleic acids (CLAs) regulate the expression of key apoptotic genes in human breast cancer cells. FASEB J 2002;16(11):1447-1449. View abstract.

Makol, A., Torrecillas, S., Fernandez-Vaquero, A., Robaina, L., Montero, D., Caballero, M. J., Tort, L., and Izquierdo, M. Effect of conjugated linoleic acid on dietary lipids utilization, liver morphology and selected immune parameters in sea bass juveniles (Dicentrarchus labrax). Comp Biochem.Physiol B Biochem.Mol.Biol. 2009;154(2):179-187. View abstract.

Mallia, S., Escher, F., Dubois, S., Schieberle, P., and Schlichtherle-Cerny, H. Characterization and quantification of odor-active compounds in unsaturated fatty acid/conjugated linoleic acid (UFA/CLA)-enriched butter and in conventional butter during storage and induced oxidation. J Agric.Food Chem. 8-26-2009;57(16):7464-7472. View abstract.

Malovrh, T., Kompan, L., Juntes, P., Wraber, B., Spindler-Vesel, A., and Kompan, D. Influence of conjugated linoleic acid on the porcine immune response and morbidity: a randomized controlled trial. Lipids Health Dis. 2009;8:22. View abstract.

Malpuech-Brugere C Verboeket-van de Venne WP, Mensink, R. P., Arnal, M. A., Morio, B., Brandolini, M., Saebo, A., Lassel, T. S., Chardigny, J. M., Sebedio, J. L., and Beaufrere, B. Effects of two conjugated linoleic Acid isomers on body fat mass in overweight humans. Obes Res 2004;12(4):591-598. View abstract.

Mandir, N. and Goodlad, R. A. Conjugated linoleic acids differentially alter polyp number and diameter in the Apc(min/+) mouse model of intestinal cancer. Cell Prolif. 2008;41(2):279-291. View abstract.

Manzano, Maria R., Colnago, L. A., Aparecida, Forato L., and Bouchard, D. Fast and simple nuclear magnetic resonance method to measure conjugated linoleic acid in beef. J Agric.Food Chem. 6-9-2010;58(11):6562-6564. View abstract.

Marion-Letellier, R., Butler, M., Dechelotte, P., Playford, R. J., and Ghosh, S. Comparison of cytokine modulation by natural peroxisome proliferator-activated receptor gamma ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells--potential for dietary modulation of peroxisome proliferator-activated receptor gamma in intestinal inflammation. Am.J Clin.Nutr 2008;87(4):939-948. View abstract.

Marounek, M., Skrivanova, V., Vyborna, A., and Duskova, D. Performance and tissue fatty acid profiles in veal calves fed diets supplemented with conjugated linoleic acids. Arch.Anim Nutr 2008;62(5):366-376. View abstract.

Martin, D., Antequera, T., Muriel, E., Perez-Palacios, T., and Ruiz, J. Volatile compounds of fresh and dry-cured loin as affected by dietary conjugated linoleic acid and monounsaturated fatty acids. Meat.Sci 10-17-2008; View abstract.

Martinasso, G., Saracino, S., Maggiora, M., Oraldi, M., Canuto, R. A., and Muzio, G. Conjugated linoleic acid prevents cell growth and cytokine production induced by TPA in human keratinocytes NCTC 2544. Cancer Lett. 1-1-2010;287(1):62-66. View abstract.

Martins, A. P., Lopes, P. A., Martins, S. V., Madeira, A., Santos, N. C., Prates, J. A., Moura, T. F., and Soveral, G. Conjugated linoleic acid reduces permeability and fluidity of adipose plasma membranes from obese Zucker rats. Biochem.Biophys.Res Commun. 7-23-2010;398(2):199-204. View abstract.

Martins, S. V., Lopes, P. A., Alfaia, C. M., Rodrigues, P. O., Alves, S. P., Pinto, R. M., Castro, M. F., Bessa, R. J., and Prates, J. A. Serum adipokine profile and fatty acid composition of adipose tissues are affected by conjugated linoleic acid and saturated fat diets in obese Zucker rats. Br.J Nutr 2010;103(6):869-878. View abstract.

Matsuda, M. and DeFronzo, R. A. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22(9):1462-1470. View abstract.

Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., and Turner, R. C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28(7):412-419. View abstract.

Maurelli, S., Blasi, F., Cossignani, L., Bosi, A., Simonetti, M. S., and Damiani, P. Enzymatic Synthesis of Structured Triacylglycerols Containing CLA Isomers Starting from sn-1,3-Diacylglycerols. JAOCS: Journal of the American Oil Chemists' Society 2009;86(2):127-133.

McCarty, M. F. Activation of PPARgamma may mediate a portion of the anticancer activity of conjugated linoleic acid. Med Hypotheses 2000;55(3):187-188. View abstract.

McClelland, S., Cox, C., O'Connor, R., de Gaetano, M., McCarthy, C., Cryan, L., Fitzgerald, D., and Belton, O. Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell. Atherosclerosis 2010;211(1):96-102. View abstract.

McClements, D. J. Design of nano-laminated coatings to control bioavailability of lipophilic food components. J Food Sci 2010;75(1):R30-R42. View abstract.

McIntosh, F. M., Shingfield, K. J., Devillard, E., Russell, W. R., and Wallace, R. J. Mechanism of conjugated linoleic acid and vaccenic acid formation in human faecal suspensions and pure cultures of intestinal bacteria. Microbiology 2009;155(Pt 1):285-294. View abstract.

McKain, N., Shingfield, K. J., and Wallace, R. J. Metabolism of conjugated linoleic acids and 18 : 1 fatty acids by ruminal bacteria: products and mechanisms. Microbiology 2010;156(Pt 2):579-588. View abstract.

McNeel, R. L., Smith, E. O., and Mersmann, H. J. Isomers of conjugated linoleic acid modulate human preadipocyte differentiation. In Vitro Cell Dev Biol Anim 2003;39(8-9):375-382. View abstract.

Meadus, W. J., MacInnis, R., and Dugan, M. E. Prolonged dietary treatment with conjugated linoleic acid stimulates porcine muscle peroxisome proliferator activated receptor gamma and glutamine-fructose aminotransferase gene expression in vivo. J Mol.Endocrinol. 2002;28(2):79-86. View abstract.

Medina, E. A., Horn, W. F., Keim, N. L., Havel, P. J., Benito, P., Kelley, D. S., Nelson, G. J., and Erickson, K. L. Conjugated linoleic acid supplementation in humans: effects on circulating leptin concentrations and appetite. Lipids 2000;35(7):783-788. View abstract.

Mele, M., Dal Zotto, R., Cassandro, M., Conte, G., Serra, A., Buccioni, A., Bittante, G., and Secchiari, P. Genetic parameters for conjugated linoleic acid, selected milk fatty acids, and milk fatty acid unsaturation of Italian Holstein-Friesian cows. J Dairy Sci 2009;92(1):392-400. View abstract.

Mendis, S., Cruz-Hernandez, C., and Ratnayake, W. M. Fatty acid profile of Canadian dairy products with special attention to the trans-octadecenoic acid and conjugated linoleic acid isomers. J AOAC Int 2008;91(4):811-819. View abstract.

Meng, X., Shoemaker, S. F., McGee, S. O., and Ip, M. M. t10,c12-Conjugated linoleic acid stimulates mammary tumor progression in Her2/ErbB2 mice through activation of both proliferative and survival pathways. Carcinogenesis 2008;29(5):1013-1021. View abstract.

Michishita, T., Kobayashi, S., Katsuya, T., Ogihara, T., and Kawabuchi, K. Evaluation of the antiobesity effects of an amino acid mixture and conjugated linoleic acid on exercising healthy overweight humans: a randomized, double-blind, placebo-controlled trial. J Int Med Res 2010;38(3):844-859. View abstract.

Milanesi, E., Nicoloso, L., and Crepaldi, P. Stearoyl CoA desaturase (SCD) gene polymorphisms in Italian cattle breeds. J Anim Breed.Genet. 2008;125(1):63-67. View abstract.

Miller, A., Stanton, C., and Devery, R. Cis 9, trans 11- and trans 10, cis 12-conjugated linoleic acid isomers induce apoptosis in cultured SW480 cells. Anticancer Res 2002;22(6C):3879-3887. View abstract.

Miller, A., Stanton, C., and Devery, R. Modulation of arachidonic acid distribution by conjugated linoleic acid isomers and linoleic acid in MCF-7 and SW480 cancer cells. Lipids 2001;36(10):1161-1168. View abstract.

Miller, A., Stanton, C., Murphy, J., and Devery, R. Conjugated linoleic acid (CLA)-enriched milk fat inhibits growth and modulates CLA-responsive biomarkers in MCF-7 and SW480 human cancer cell lines. Br J Nutr 2003;90(5):877-885. View abstract.

Miller, J. R., Siripurkpong, P., Hawes, J., Majdalawieh, A., Ro, H. S., and McLeod, R. S. The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARgamma-dependent and PPARgamma-independent mechanisms. J Lipid Res 2008;49(3):550-562. View abstract.

Miller, W. F., Shirley, J. E., Titgemeyer, E. C., and Brouk, M. J. Comparison of full-fat corn germ, whole cottonseed, and tallow as fat sources for lactating dairy cattle. J Dairy Sci 2009;92(7):3386-3391. View abstract.

Mir, P. S., Dugan, M. E., He, M. L., Entz, T., and Yip, B. Effects of dietary sunflower seeds and tylosin phosphate on production variables, carcass characteristics, fatty acid composition, and liver abscess incidence in crossbred steers. J Anim Sci 2008;86(11):3125-3136. View abstract.

Mir, P. S., McAllister, T. A., Scott, S., Aalhus, J., Baron, V., McCartney, D., Charmley, E., Goonewardene, L., Basarab, J., Okine, E., Weselake, R. J., and Mir, Z. Conjugated linoleic acid-enriched beef production. Am J Clin Nutr 2004;79(6 Suppl):1207S-1211S. View abstract.

Miranda, J., Churruca, I., Fernandez-Quintela, A., Rodriguez, V. M., Macarulla, M. T., Simon, E., and Portillo, M. P. Weak effect of trans-10, cis-12-conjugated linoleic acid on body fat accumulation in adult hamsters. Br.J Nutr 2009;102(11):1583-1589. View abstract.

Miranda, J., Fernandez-Quintela, A., Churruca, I., Rodriguez, V. M., Simon, E., and Portillo, M. P. Hepatomegaly induced by trans-10,cis-12 conjugated linoleic acid in adult hamsters fed an atherogenic diet is not associated with steatosis. J Am.Coll.Nutr 2009;28(1):43-49. View abstract.

Miranda, J., Fernandez-Quintela, A., Macarulla, M. T., Churruca, I., Garcia, C., Rodriguez, V. M., Simon, E., and Portillo, M. P. A comparison between CLNA and CLA effects on body fat, serum parameters and liver composition. J Physiol Biochem. 2009;65(1):25-32. View abstract.

Mitchell, P. L. and McLeod, R. S. Conjugated linoleic acid and atherosclerosis: studies in animal models. Biochem.Cell Biol. 2008;86(4):293-301. View abstract.

Mitchell, P. L., Langille, M. A., Currie, D. L., and McLeod, R. S. Effect of conjugated linoleic acid isomers on lipoproteins and atherosclerosis in the Syrian Golden hamster. Biochim.Biophys.Acta 6-1-2005;1734(3):269-276. View abstract.

Mitmesser, S. H. and Carr, T. P. Trans fatty acids alter the lipid composition and size of apoB-100-containing lipoproteins secreted by HepG2 cells. J Nutr Biochem 2005;16(3):178-183. View abstract.

Mizunoya, W., Haramizu, S., Shibakusa, T., Okabe, Y., and Fushiki, T. Dietary conjugated linoleic acid increases endurance capacity and fat oxidation in mice during exercise. Lipids 2005;40(3):265-271. View abstract.

Moate, P. J., Boston, R. C., Jenkins, T. C., and Lean, I. J. Kinetics of ruminal lipolysis of triacylglycerol and biohydrogenation of long-chain fatty acids: new insights from old data. J Dairy Sci 2008;91(2):731-742. View abstract.

Moate, P. J., Chalupa, W., Boston, R. C., and Lean, I. J. Milk fatty acids II: prediction of the production of individual fatty acids in bovine milk. J Dairy Sci 2008;91(3):1175-1188. View abstract.

Mohammed, R., Stanton, C. S., Kennelly, J. J., Kramer, J. K., Mee, J. F., Glimm, D. R., O'Donovan, M., and Murphy, J. J. Grazing cows are more efficient than zero-grazed and grass silage-fed cows in milk rumenic acid production. J Dairy Sci 2009;92(8):3874-3893. View abstract.

Molina-Alcaide, E., Morales-Garcia, E. Y., Martin-Garcia, A. I., Ben Salem, H., Nefzaoui, A., and Sanz-Sampelayo, M. R. Effects of partial replacement of concentrate with feed blocks on nutrient utilization, microbial N flow, and milk yield and composition in goats. J Dairy Sci 2010;93(5):2076-2087. View abstract.

Moloney, F., Yeow, T. P., Mullen, A., Nolan, J. J., and Roche, H. M. Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am J Clin Nutr 2004;80(4):887-895. View abstract.

Molto-Puigmarti, C., Castellote, A. I., and Lopez-Sabater, M. C. Conjugated linoleic acid determination in human milk by fast-gas chromatography. Anal.Chim.Acta 10-17-2007;602(1):122-130. View abstract.

Moon, H. S., Lee, H. G., Chung, C. S., Choi, Y. J., and Cho, C. S. Physico-chemical modifications of conjugated linoleic acid for ruminal protection and oxidative stability. Nutr Metab (Lond) 2008;5:16. View abstract.

Moon, H. S., Lee, H. G., Seo, J. H., Chung, C. S., Guo, D. D., Kim, T. G., Choi, Y. J., and Cho, C. S. Leptin-induced matrix metalloproteinase-2 secretion is suppressed by trans-10,cis-12 conjugated linoleic acid. Biochem.Biophys.Res Commun. 5-18-2007;356(4):955-960. View abstract.

Morales-Almaraz, E., Soldado, A., Gonzalez, A., Martinez-Fernandez, A., Dominguez-Vara, I., Roza-Delgado, B., and Vicente, F. Improving the fatty acid profile of dairy cow milk by combining grazing with feeding of total mixed ration. J Dairy Res 2010;77(2):225-230. View abstract.

Morel, P. C., Janz, J. A., Zou, M., Purchas, R. W., Hendriks, W. H., and Wilkinson, B. H. The influence of diets supplemented with conjugated linoleic acid, selenium, and vitamin E, with or without animal protein, on the composition of pork from female pigs. J Anim Sci 2008;86(5):1145-1155. View abstract.

Morre, J. and Morre, D. M. Omega-3 but not omega-6 unsaturated fatty acids inhibit the cancer-specific ENOX2 of the HeLa cell surface with no effect on the constitutive ENOX1. Journal of Dietary Supplements 2010;7(2):154-158.

Moutsioulis, A. A., Rule, D. C., Murrieta, C. M., Bauman, D. E., Lock, A. L., Barbano, D. M., and Carey, G. B. Human breast milk enrichment in conjugated linoleic acid after consumption of a conjugated linoleic acid-rich food product: a pilot study. Nutr Res 2008;28(7):437-442. View abstract.

Moya-Camarena, S. Y., Vanden Heuvel, J. P., Blanchard, S. G., Leesnitzer, L. A., and Belury, M. A. Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPARalpha. J Lipid Res 1999;40(8):1426-1433. View abstract.

Muller, A., Ringseis, R., Dusterloh, K., Gahler, S., Eder, K., and Steinhart, H. Detection of conjugated dienoic fatty acids in human vascular smooth muscle cells treated with conjugated linoleic acid. Biochim.Biophys Acta 12-15-2005;1737(2-3):145-151. View abstract.

Munday, J. S., Thompson, K. G., and James, K. A. Dietary conjugated linoleic acids promote fatty streak formation in the C57BL/6 mouse atherosclerosis model. Br J Nutr 1999;81(3):251-255. View abstract.

Murphy, E. F., Hooiveld, G. J., Muller, M., Calogero, R. A., and Cashman, K. D. Conjugated linoleic acid alters global gene expression in human intestinal-like Caco-2 cells in an isomer-specific manner. J Nutr 2007;137(11):2359-2365. View abstract.

Murphy, E. F., Hooiveld, G. J., Muller, M., Calogero, R. A., and Cashman, K. D. The effect of trans-10, cis-12 conjugated linoleic acid on gene expression profiles related to lipid metabolism in human intestinal-like Caco-2 cells. Genes Nutr 2009;4(2):103-112. View abstract.

Murphy, E. F., Jewell, C., Hooiveld, G. J., Muller, M., and Cashman, K. D. Conjugated linoleic acid enhances transepithelial calcium transport in human intestinal-like Caco-2 cells: an insight into molecular changes. Prostaglandins Leukot.Essent.Fatty Acids 2006;74(5):295-301. View abstract.

Muzio, G., Maggiora, M., Oraldi, M., Trombetta, A., and Canuto, R. A. PPARalpha and PP2A are involved in the proapoptotic effect of conjugated linoleic acid on human hepatoma cell line SK-HEP-1. Int J Cancer 12-1-2007;121(11):2395-2401. View abstract.

Nagao, K., Inoue, N., Ujino, Y., Higa, K., Shirouchi, B., Wang, Y. M., and Yanagita, T. Effect of leptin infusion on insulin sensitivity and lipid metabolism in diet-induced lipodystrophy model mice. Lipids Health Dis. 2008;7:8. View abstract.

Nagao, K., Inoue, N., Wang, Y. M., Hirata, J., Shimada, Y., Nagao, T., Matsui, T., and Yanagita, T. The 10trans,12cis isomer of conjugated linoleic acid suppresses the development of hypertension in Otsuka Long-Evans Tokushima fatty rats. Biochem.Biophys.Res Commun. 6-20-2003;306(1):134-138. View abstract.

Nagao, K., Inoue, N., Wang, Y. M., Shirouchi, B., and Yanagita, T. Dietary conjugated linoleic acid alleviates nonalcoholic fatty liver disease in Zucker (fa/fa) rats. J.Nutr. 2005;135(1):9-13. View abstract.

Nagao, K., Wang, Y. M., Inoue, N., Han, S. Y., Buang, Y., Noda, T., Kouda, N., Okamatsu, H., and Yanagita, T. The 10trans, 12cis isomer of conjugated linoleic acid promotes energy metabolism in OLETF rats. Nutrition 2003;19(7-8):652-656. View abstract.

Nakamura, Y. K. and Omaye, S. T. Conjugated linoleic acid isomers' roles in the regulation of PPAR-gamma and NF-kappaB DNA binding and subsequent expression of antioxidant enzymes in human umbilical vein endothelial cells. Nutrition 2009;25(7-8):800-811. View abstract.

Nakamura, Y. K., Flintoff-Dye, N., and Omaye, S. T. Conjugated linoleic acid modulation of risk factors associated with atherosclerosis. Nutr Metab (Lond) 2008;5:22. View abstract.

Nakanishi, T., Koutoku, T., Kawahara, S., Murai, A., and Furuse, M. Dietary conjugated linoleic acid reduces cerebral prostaglandin E(2) in mice. Neurosci.Lett. 5-1-2003;341(2):135-138. View abstract.

Nam, I. S. and Garnsworthy, P. C. Biohydrogenation of linoleic acid by rumen fungi compared with rumen bacteria. J Appl.Microbiol. 2007;103(3):551-556. View abstract.

Nam, I. S. and Garnsworthy, P. C. Factors influencing biohydrogenation and conjugated linoleic acid production by mixed rumen fungi. J Microbiol. 2007;45(3):199-204. View abstract.

Naumann, E., Carpentier, Y. A., Saebo, A., Lassel, T. S., Chardigny, J. M., Sebedio, J. L., and Mensink, R. P. Cis-9, trans- 11 and trans-10, cis-12 conjugated linoleic acid (CLA) do not affect the plasma lipoprotein profile in moderately overweight subjects with LDL phenotype B. Atherosclerosis 2006;188(1):167-174. View abstract.

Navarro, M. A., Badimon, L., Rodriguez, C., Arnal, C., Noone, E. J., Roche, H. M., Osada, J., and Martinez-Gonzalez, J. Trans-10,cis-12-CLA dysregulate lipid and glucose metabolism and induce hepatic NR4A receptors. Front Biosci.(Elite.Ed) 2010;2:87-97. View abstract.

Navarro, V., Macarulla, M. T., Fernandez-Quintela, A., Rodriguez, V. M., Simon, E., and Portillo, M. P. Effects of trans-10,cis-12 conjugated linoleic acid on cholesterol metabolism in hypercholesterolaemic hamsters. Eur J Nutr 2007;46(4):213-219. View abstract.

Navarro, V., Portillo, M. P., Margotat, A., Landrier, J. F., Macarulla, M. T., Lairon, D., and Martin, J. C. A multi-gene analysis strategy identifies metabolic pathways targeted by trans-10, cis-12-conjugated linoleic acid in the liver of hamsters. Br.J Nutr 2009;102(4):537-545. View abstract.

Nazare, J. A., de la Perriere, A. B., Bonnet, F., Desage, M., Peyrat, J., Maitrepierre, C., Louche-Pelissier, C., Bruzeau, J., Goudable, J., Lassel, T., Vidal, H., and Laville, M. Daily intake of conjugated linoleic acid-enriched yoghurts: effects on energy metabolism and adipose tissue gene expression in healthy subjects. Br.J Nutr 2007;97(2):273-280. View abstract.

Nelson, K. A. and Martini, S. Increasing omega fatty acid content in cow's milk through diet manipulation: effect on milk flavor. J Dairy Sci 2009;92(4):1378-1386. View abstract.

Nicolosi, R. J., Rogers, E. J., Kritchevsky, D., Scimeca, J. A., and Huth, P. J. Dietary conjugated linoleic acid reduces plasma lipoproteins and early aortic atherosclerosis in hypercholesterolemic hamsters. Artery 1997;22(5):266-277. View abstract.

Nie, L., Ren, Y., Janakiraman, A., Smith, S., and Schulz, H. A novel paradigm of fatty acid beta-oxidation exemplified by the thioesterase-dependent partial degradation of conjugated linoleic acid that fully supports growth of Escherichia coli. Biochemistry 9-9-2008;47(36):9618-9626. View abstract.

Niu, X. Y., Chen, W., Tian, F. W., Zhao, J. X., and Zhang, H. [Bioconversion of conjugated linoleic acid by resting cells of Lactobacillus plantarum ZS2058 in potassium phosphate buffer system]. Wei Sheng Wu Xue.Bao. 2007;47(2):244-248. View abstract.

Noci, F., Monahan, F. J., Scollan, N. D., and Moloney, A. P. The fatty acid composition of muscle and adipose tissue of steers offered unwilted or wilted grass silage supplemented with sunflower oil and fishoil. Br.J Nutr 2007;97(3):502-513. View abstract.

Noone, E. J., Roche, H. M., Nugent, A. P., and Gibney, M. J. The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. Br J Nutr 2002;88(3):243-251. View abstract.

Norris, L. E., Collene, A. L., Asp, M. L., Hsu, J. C., Liu, L. F., Richardson, J. R., Li, D., Bell, D., Osei, K., Jackson, R. D., and Belury, M. A. Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus. Am.J Clin.Nutr 2009;90(3):468-476. View abstract.

Noto, A., Zahradka, P., Yurkova, N., Xie, X., Truong, H., Nitschmann, E., Ogborn, M. R., and Taylor, C. G. Dietary conjugated linoleic acid decreases adipocyte size and favorably modifies adipokine status and insulin sensitivity in obese, insulin-resistant rats. Metabolism 2007;56(12):1601-1611. View abstract.

纽伦堡,K。丹嫩贝格,D。安德,K,怒ernberg, G. Comparison of different methylation methods for the analysis of conjugated linoleic acid isomers by silver ion HPLC in beef lipids. J Agric.Food Chem. 2-7-2007;55(3):598-602. View abstract.

Nugent, A. P., Roche, H. M., Noone, E. J., Long, A., Kelleher, D. K., and Gibney, M. J. The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers. Eur.J Clin Nutr 2005;59(6):742-750. View abstract.

Nunes, E. A., Bonatto, S. J., de Oliveira, H. H., Rivera, N. L., Maiorka, A., Krabbe, E. L., Tanhoffer, R. A., and Fernandes, L. C. The effect of dietary supplementation with 9-cis:12-trans and 10-trans:12-cis conjugated linoleic acid (CLA) for nine months on serum cholesterol, lymphocyte proliferation and polymorphonuclear cells function in Beagle dogs. Res Vet.Sci 2008;84(1):62-67. View abstract.

O'Donnell, A. M., Spatny, K. P., Vicini, J. L., and Bauman, D. E. Survey of the fatty acid composition of retail milk differing in label claims based on production management practices. J Dairy Sci 2010;93(5):1918-1925. View abstract.

O'Hagan, S. and Menzel, A. A subchronic 90-day oral rat toxicity study and in vitro genotoxicity studies with a conjugated linoleic acid product. Food Chem Toxicol. 2003;41(12):1749-1760. View abstract.

O'Shea, M., Bassaganya-Riera, J., and Mohede, I. C. Immunomodulatory properties of conjugated linoleic acid. Am J Clin Nutr 2004;79(6 Suppl):1199S-1206S. View abstract.

O'Shea, M., Devery, R., Lawless, F., Murphy, J., and Stanton, C. Milk fat conjugated linoleic acid (CLA) inhibits growth of human mammary MCF-7 cancer cells. Anticancer Res 2000;20(5B):3591-3601. View abstract.

Obinata, H. and Izumi, T. G2A as a receptor for oxidized free fatty acids. Prostaglandins Other Lipid Mediat. 2009;89(3-4):66-72. View abstract.

Odongo, N. E., Or-Rashid, M. M., Kebreab, E., France, J., and McBride, B. W. Effect of supplementing myristic acid in dairy cow rations on ruminal methanogenesis and fatty acid profile in milk. J Dairy Sci 2007;90(4):1851-1858. View abstract.

Oelker, E. R., Reveneau, C., and Firkins, J. L. Interaction of molasses and monensin in alfalfa hay- or corn silage-based diets on rumen fermentation, total tract digestibility, and milk production by Holstein cows. J Dairy Sci 2009;92(1):270-285. View abstract.

Ogawa, A., Obinata, H., Hattori, T., Kishi, M., Tatei, K., Ishikawa, O., and Izumi, T. Identification and analysis of two splice variants of human G2A generated by alternative splicing. J Pharmacol.Exp.Ther 2010;332(2):469-478. View abstract.

Ogawa, J., Kishino, S., Ando, A., Sugimoto, S., Mihara, K., and Shimizu, S. Production of conjugated fatty acids by lactic acid bacteria. J Biosci.Bioeng. 2005;100(4):355-364. View abstract.

Ogborn, M. R., Nitschmann, E., Goldberg, A., Bankovic-Calic, N., Weiler, H. A., and Aukema, H. M. Dietary conjugated linoleic acid renal benefits and possible toxicity vary with isomer, dose and gender in rat polycystic kidney disease. Lipids 2008;43(9):783-791. View abstract.

Oh, Y. S., Lee, H. S., Cho, H. J., Lee, S. G., Jung, K. C., and Park, J. H. Conjugated linoleic acid inhibits DNA synthesis and induces apoptosis in TSU-Pr1 human bladder cancer cells. Anticancer Res 2003;23(6C):4765-4772. View abstract.

Oikawa, D., Nakanishi, T., Nakamura, Y., Takahashi, Y., Yamamoto, T., Shiba, N., Tobisa, M., Takagi, T., Iwamoto, H., Tachibana, T., and Furuse, M. Dietary CLA and DHA modify skin properties in mice. Lipids 2003;38(6):609-614. View abstract.

Oliveira, R. P., Florence, A. C., Silva, R. C., Perego, P., Converti, A., Gioielli, L. A., and Oliveira, M. N. Effect of different prebiotics on the fermentation kinetics, probiotic survival and fatty acids profiles in nonfat symbiotic fermented milk. Int J Food Microbiol. 1-15-2009;128(3):467-472. View abstract.

奥丽,年代Leroux、C。de la,弗耶,伯纳德。L。, Rouel, J., and Chilliard, Y. Whole intact rapeseeds or sunflower oil in high-forage or high-concentrate diets affects milk yield, milk composition, and mammary gene expression profile in goats. J Dairy Sci 2009;92(11):5544-5560. View abstract.

Or-Rashid, M. M., AlZahal, O., and McBride, B. W. Studies on the production of conjugated linoleic acid from linoleic and vaccenic acids by mixed rumen protozoa. Appl.Microbiol.Biotechnol. 2008;81(3):533-541. View abstract.

Or-Rashid, M. M., Kramer, J. K., Wood, M. A., and McBride, B. W. Supplemental algal meal alters the ruminal trans-18:1 fatty acid and conjugated linoleic acid composition in cattle. J Anim Sci 2008;86(1):187-196. View abstract.

Or-Rashid, M. M., Odongo, N. E., and McBride, B. W. Fatty acid composition of ruminal bacteria and protozoa, with emphasis on conjugated linoleic acid, vaccenic acid, and odd-chain and branched-chain fatty acids. J Anim Sci 2007;85(5):1228-1234. View abstract.

Or-Rashid, M. M., Odongo, N. E., Subedi, B., Karki, P., and McBride, B. W. Fatty acid composition of yak (Bos grunniens) cheese including conjugated linoleic acid and trans-18:1 fatty acids. J Agric.Food Chem. 3-12-2008;56(5):1654-1660. View abstract.

Or-Rashid, M. M., Odongo, N. E., Wright, T. C., and McBride, B. W. Fatty acid profile of bovine milk naturally enhanced with docosahexaenoic acid. J Agric.Food Chem. 2-25-2009;57(4):1366-1371. View abstract.

Ortiz, B., Wassef, L., Shabrova, E., Cordeddu, L., Banni, S., and Quadro, L. Hepatic retinol secretion and storage are altered by dietary CLA: common and distinct actions of CLA c9,t11 and t10,c12 isomers. J Lipid Res 2009;50(11):2278-2289. View abstract.

Ostrowska, E., Cross, R. F., Muralitharan, M., Bauman, D. E., and Dunshea, F. R. Effects of dietary fat and conjugated linoleic acid on plasma metabolite concentrations and metabolic responses to homeostatic signals in pigs. Br J Nutr 2002;88(6):625-634. View abstract.

Ou, L., Ip, C., Lisafeld, B., and Ip, M. M. Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss. Biochem.Biophys.Res Commun. 5-18-2007;356(4):1044-1049. View abstract.

Ou, L., Wu, Y., Ip, C., Meng, X., Hsu, Y. C., and Ip, M. M. Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response. J Lipid Res 2008;49(5):985-994. View abstract.

Paek, J., Kang, J. H., Kim, S. S., Son, K. A., Park, M. R., and Yang, M. P. Trans-10, cis-12 conjugated linoleic acid directly enhances the chemotactic activity of porcine peripheral blood polymorphonuclear neutrophillic leukocytes by activating F-actin polymerization in vitro. Res Vet.Sci 2010;89(2):191-195. View abstract.

Pajunen, T. I., Koskela, H., Hase, T., and Hopia, A. NMR properties of conjugated linoleic acid (CLA) methyl ester hydroperoxides. Chem.Phys.Lipids 2008;154(2):105-114. View abstract.

Pakdeechanuan, P., Intarapichet, K. O., and Tongta, S. Effect of extrusion parameters on conjugated linoleic acids of corn extrudates. J Agric.Food Chem. 2-21-2007;55(4):1463-1468. View abstract.

Pal, S., Takechi, R., and Ho, S. S. Conjugated linoleic acid suppresses the secretion of atherogenic lipoproteins from human HepG2 liver cells. Clin Chem Lab Med 2005;43(3):269-274. View abstract.

Palacios, A., Piergiacomi, V., and Catala, A. Antioxidant effect of conjugated linoleic acid and vitamin A during non enzymatic lipid peroxidation of rat liver microsomes and mitochondria. Mol.Cell Biochem. 2003;250(1-2):107-113. View abstract.

帕拉迪诺,R·巴克利,F。,Prendiville, R。μrphy, J. J., Callan, J., and Kenny, D. A. A comparison between Holstein-Friesian and Jersey dairy cows and their F(1) hybrid on milk fatty acid composition under grazing conditions. J Dairy Sci 2010;93(5):2176-2184. View abstract.

Palladino, R. A., O'Donovan, M., Murphy, J. J., McEvoy, M., Callan, J., Boland, T. M., and Kenny, D. A. Fatty acid intake and milk fatty acid composition of Holstein dairy cows under different grazing strategies: herbage mass and daily herbage allowance. J Dairy Sci 2009;92(10):5212-5223. View abstract.

Palombo, J. D., Ganguly, A., Bistrian, B. R., and Menard, M. P. The antiproliferative effects of biologically active isomers of conjugated linoleic acid on human colorectal and prostatic cancer cells. Cancer Lett 3-28-2002;177(2):163-172. View abstract.

Paradis, C., Berthiaume, R., Lafreniere, C., Gervais, R., and Chouinard, P. Y. Conjugated linoleic acid content in adipose tissue of calves suckling beef cows on pasture and supplemented with raw or extruded soybeans. J Anim Sci 2008;86(7):1624-1636. View abstract.

Pariza, M. W. Conjugated linoleic acid may be useful in treating diabetes by controlling body fat and weight gain. Diabetes Technol Ther 2002;4(3):335-338. View abstract.

Pariza, M. W. Perspective on the safety and effectiveness of conjugated linoleic acid. Am J Clin Nutr 2004;79(6 Suppl):1132S-1136S. View abstract.

Pariza, M. W., Park, Y., and Cook, M. E. The biologically active isomers of conjugated linoleic acid. Prog Lipid Res 2001;40(4):283-298. View abstract.

Park, H. G., Cho, S. D., Kim, J. H., Lee, H., Chung, S. H., Kim, S. B., Kim, H. S., Kim, T., Choi, N. J., and Kim, Y. J. Characterization of conjugated linoleic acid production by Bifidobacterium breve LMC 520. J Agric.Food Chem. 8-26-2009;57(16):7571-7575. View abstract.

公园,H·S。曹,H . Y。哈,Y L。,和公园,j . H。Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. J Nutr Biochem. 2004;15(4):229-235. View abstract.

Park, H. S., Chun, C. S., Kim, S., Ha, Y. L., and Park, J. H. Dietary trans-10, cis-12 and cis-9,trans-11 Conjugated Linoleic Acids Induce Apoptosis in the Colonic Mucosa of Rats Treated with 1,2-Dimethylhydrazine. J Med Food 2006;9(1):22-27. View abstract.

Park, N. Y., Valacchi, G., and Lim, Y. Effect of dietary conjugated linoleic acid supplementation on early inflammatory responses during cutaneous wound healing. Mediators.Inflamm. 2010;2010 View abstract.

Park, Y. and Park, Y. Conjugated nonadecadienoic acid is more potent than conjugated linoleic acid on body fat reduction. J Nutr Biochem. 2010;21(8):764-773. View abstract.

Park, Y., Albright, K. J., Liu, W., Storkson, J. M., Cook, M. E., and Pariza, M. W. Effect of conjugated linoleic acid on body composition in mice. Lipids 1997;32(8):853-858. View abstract.

Park, Y., Albright, K. J., Storkson, J. M., Liu, W., and Pariza, M. W. Conjugated linoleic acid (CLA) prevents body fat accumulation and weight gain in an animal model. J Food Sci 2007;72(8):S612-S617. View abstract.

Park, Y., Storkson, J. M., Albright, K. J., Liu, W., and Pariza, M. W. Biological activities of conjugated fatty acids: conjugated eicosadienoic (conj. 20:2delta(c11,t13/t12,c14)), eicosatrienoic (conj. 20:3delta(c8,t12,c14)), and heneicosadienoic (conj. 21:2delta(c12,t14/c13,t15)) acids and other metabolites of conjugated linoleic acid. Biochim.Biophys.Acta 2-21-2005;1687(1-3):120-129. View abstract.

Park, Y., Terk, M., and Park, Y. Interaction between dietary conjugated linoleic acid and calcium supplementation affecting bone and fat mass. J Bone Miner.Metab 8-10-2010; View abstract.

Parra, P., Palou, A., and Serra, F. Moderate doses of conjugated linoleic acid reduce fat gain, maintain insulin sensitivity without impairing inflammatory adipose tissue status in mice fed a high-fat diet. Nutr Metab (Lond) 2010;7:5. View abstract.

Parra, P., Serra, F., and Palou, A. Moderate doses of conjugated linoleic acid isomers mix contribute to lowering body fat content maintaining insulin sensitivity and a noninflammatory pattern in adipose tissue in mice. J Nutr Biochem. 2010;21(2):107-115. View abstract.

Patra, A. K. and Saxena, J. Dietary phytochemicals as rumen modifiers: a review of the effects on microbial populations. Antonie Van Leeuwenhoek 2009;96(4):363-375. View abstract.

Patra, A. K. and Saxena, J. Exploitation of dietary tannins to improve rumen metabolism and ruminant nutrition. J Sci Food Agric. 9-2-2010; View abstract.

Peng, Y. S., Brown, M. A., Wu, J. P., and Liu, Z. Different oilseed supplements alter fatty acid composition of different adipose tissues of adult ewes. Meat.Sci 2010;85(3):542-549. View abstract.

Pereira, R. M., Baptista, M. C., Vasques, M. I., Horta, A. E., Portugal, P. V., Bessa, R. J., Silva, J. C., Pereira, M. S., and Marques, C. C. Cryosurvival of bovine blastocysts is enhanced by culture with trans-10 cis-12 conjugated linoleic acid (10t,12c CLA). Anim Reprod.Sci 2007;98(3-4):293-301. View abstract.

Pereira, R. M., Carvalhais, I., Pimenta, J., Baptista, M. C., Vasques, M. I., Horta, A. E., Santos, I. C., Marques, M. R., Reis, A., Pereira, M. S., and Marques, C. C. Biopsied and vitrified bovine embryos viability is improved by trans10, cis12 conjugated linoleic acid supplementation during in vitro embryo culture. Anim Reprod.Sci 2008;106(3-4):322-332. View abstract.

Perez-Cano, F. J., Ramirez-Santana, C., Molero-Luis, M., Castell, M., Rivero, M., Castellote, C., and Franch, A. Mucosal IgA increase in rats by continuous CLA feeding during suckling and early infancy. J Lipid Res 2009;50(3):467-476. View abstract.

Perez-Matute, P., Marti, A., Martinez, J. A., Fernandez-Otero, M. P., Stanhope, K. L., Havel, P. J., and Moreno-Aliaga, M. J. Conjugated linoleic acid inhibits glucose metabolism, leptin and adiponectin secretion in primary cultured rat adipocytes. Mol.Cell Endocrinol. 3-30-2007;268(1-2):50-58. View abstract.

Perfield, J. W., Lock, A. L., Griinari, J. M., Saebo, A., Delmonte, P., Dwyer, D. A., and Bauman, D. E. Trans-9, cis-11 conjugated linoleic acid reduces milk fat synthesis in lactating dairy cows. J Dairy Sci 2007;90(5):2211-2218. View abstract.

Perseghin, G., Caumo, A., Caloni, M., Testolin, G., and Luzi, L. Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals. J Clin.Endocrinol.Metab 2001;86(10):4776-4781. View abstract.

Peterson, K. M., O'Shea, M., Stam, W., Mohede, I. C., Patrie, J. T., and Hayden, F. G. Effects of dietary supplementation with conjugated linoleic acid on experimental human rhinovirus infection and illness. Antivir.Ther 2009;14(1):33-43. View abstract.

Petridou, A., Mougios, V., and Sagredos, A. Supplementation with CLA: isomer incorporation into serum lipids and effect on body fat of women. Lipids 2003;38(8):805-811. View abstract.

Petrik, M. B., McEntee, M. F., Johnson, B. T., Obukowicz, M. G., and Whelan, J. Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. J Nutr 2000;130(10):2434-2443. View abstract.

Pinkoski, C., Chilibeck, P. D., Candow, D. G., Esliger, D., Ewaschuk, J. B., Facci, M., Farthing, J. P., and Zello, G. A. The effects of conjugated linoleic acid supplementation during resistance training. Med Sci Sports Exerc. 2006;38(2):339-348. View abstract.

Platt, I. and El Sohemy, A. Effects of 9cis,11trans and 10trans,12cis CLA on osteoclast formation and activity from human CD14+ monocytes. Lipids Health Dis. 2009;8:15. View abstract.

Platt, I. D. and El Sohemy, A. Regulation of osteoblast and adipocyte differentiation from human mesenchymal stem cells by conjugated linoleic acid. J Nutr Biochem. 2009;20(12):956-964. View abstract.

Platt, I., Rao, L. G., and El Sohemy, A. Isomer-specific effects of conjugated linoleic acid on mineralized bone nodule formation from human osteoblast-like cells. Exp.Biol.Med (Maywood.) 2007;232(2):246-252. View abstract.

Poirier, H., Niot, I., Clement, L., Guerre-Millo, M., and Besnard, P. Development of conjugated linoleic acid (CLA)-mediated lipoatrophic syndrome in the mouse. Biochimie 2005;87(1):73-79. View abstract.

Poirier, H., Rouault, C., Clement, L., Niot, I., Monnot, M. C., Guerre-Millo, M., and Besnard, P. Hyperinsulinaemia triggered by dietary conjugated linoleic acid is associated with a decrease in leptin and adiponectin plasma levels and pancreatic beta cell hyperplasia in the mouse. Diabetologia 2005;48(6):1059-1065. View abstract.

Politis, I., Dimopoulou, M., Voudouri, A., Noikokyris, P., and Feggeros, K. Effects of dietary conjugated linoleic acid isomers on several functional properties of macrophages and heterophils in laying hens. Br Poult.Sci 2003;44(2):203-210. View abstract.

Prais, Botelho A., Santos-Zago, L. F., and Costa, de Oliveira. Conjugated linoleic acid supplementation modified the body composition and serum leptin levels in weaning rats. Arch.Latinoam.Nutr 2008;58(2):156-163. View abstract.

Prandini, A., Sigolo, S., and Piva, G. Conjugated linoleic acid (CLA) and fatty acid composition of milk, curd and Grana Padano cheese in conventional and organic farming systems. J Dairy Res 2009;76(3):278-282. View abstract.

Precht, D. and Molkentin, J. C18:1, C18:2 and C18:3 trans and cis fatty acid isomers including conjugated cis delta 9, trans delta 11 linoleic acid (CLA) as well as total fat composition of German human milk lipids. Nahrung 1999;43(4):233-244. View abstract.

Priore, P., Giudetti, A. M., Natali, F., Gnoni, G. V., and Geelen, M. J. Metabolism and short-term metabolic effects of conjugated linoleic acids in rat hepatocytes. Biochim.Biophys.Acta 2007;1771(10):1299-1307. View abstract.

Pufulete, M. Intake of dairy products and risk of colorectal neoplasia. Nutr Res Rev 2008;21(1):56-67. View abstract.

Chaitanya Puniya, a K,年代,Tyagi, a·K·德·S。, and Singh, K. Conjugated linoleic acid producing potential of lactobacilli isolated from the rumen of cattle. J Ind.Microbiol.Biotechnol. 2008;35(11):1223-1228. View abstract.

Purushotham, A., Shrode, G. E., Wendel, A. A., Liu, L. F., and Belury, M. A. Conjugated linoleic acid does not reduce body fat but decreases hepatic steatosis in adult Wistar rats. J Nutr Biochem. 2007;18(10):676-684. View abstract.

Purushotham, A., Wendel, A. A., Liu, L. F., and Belury, M. A. Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. J Lipid Res 2007;48(2):444-452. View abstract.

Qin, H., Li, Y., Shi, L., and Sun, C. [Effect of t10, c12-conjugated linoleic acid on fatty acid metabolism in C2C12 myotubes]. Wei Sheng Yan.Jiu. 2009;38(3):355-358. View abstract.

Qin, H., Liu, Y., Lu, N., Li, Y., and Sun, C. H. cis-9,trans-11-Conjugated Linoleic Acid Activates AMP-Activated Protein Kinase in Attenuation of Insulin Resistance in C(2)C(12) Myotubes. J Agric.Food Chem. 4-13-2009; View abstract.

Racine, N. M., Watras, A. C., Carrel, A. L., Allen, D. B., McVean, J. J., Clark, R. R., O'Brien, A. R., O'Shea, M., Scott, C. E., and Schoeller, D. A. Effect of conjugated linoleic acid on body fat accretion in overweight or obese children. Am.J Clin.Nutr 2010;91(5):1157-1164. View abstract.

Raff, M., Tholstrup, T., Basu, S., Nonboe, P., Sorensen, M. T., and Straarup, E. M. A diet rich in conjugated linoleic acid and butter increases lipid peroxidation but does not affect atherosclerotic, inflammatory, or diabetic risk markers in healthy young men. J Nutr 2008;138(3):509-514. View abstract.

Raff, M., Tholstrup, T., Sejrsen, K., Straarup, E. M., and Wiinberg, N. Diets rich in conjugated linoleic acid and vaccenic acid have no effect on blood pressure and isobaric arterial elasticity in healthy young men. J Nutr 2006;136(4):992-997. View abstract.

Raff, M., Tholstrup, T., Toubro, S., Bruun, J. M., Lund, P., Straarup, E. M., Christensen, R., Sandberg, M. B., and Mandrup, S. Conjugated linoleic acids reduce body fat in healthy postmenopausal women. J Nutr 2009;139(7):1347-1352. View abstract.

Rahman, M. M., Bhattacharya, A., Banu, J., and Fernandes, G. Conjugated linoleic acid protects against age-associated bone loss in C57BL/6 female mice. J Nutr Biochem. 2007;18(7):467-474. View abstract.

Rahman, M., Halade, G. V., El Jamali, A., and Fernandes, G. Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle loss. Biochem.Biophys.Res Commun. 6-12-2009;383(4):513-518. View abstract.

Rahman, S. M., Huda, M. N., Uddin, M. N., and Akhteruzzaman, S. Short-term administration of conjugated linoleic acid reduces liver triglyceride concentration and phosphatidate phosphohydrolase activity in OLETF rats. J Biochem.Mol.Biol 9-30-2002;35(5):494-497. View abstract.

Ramirez-Santana, C., Castellote, C., Castell, M., Molto-Puigmarti, C., Rivero, M., Perez-Cano, F. J., and Franch, A. Enhancement of antibody synthesis in rats by feeding cis-9,trans-11 conjugated linoleic acid during early life. J Nutr Biochem. 8-4-2010; View abstract.

Ramirez-Santana, C., Castellote, C., Castell, M., Rivero, M., Rodriguez-Palmero, M., Franch, A., and Perez-Cano, F. J. Long-term feeding of the cis-9,trans-11 isomer of conjugated linoleic acid reinforces the specific immune response in rats. J Nutr 2009;139(1):76-81. View abstract.

Ramos, R., Mascarenhas, J., Duarte, P., Vicente, C., and Casteleiro, C. Conjugated linoleic acid-induced toxic hepatitis: first case report. Dig.Dis.Sci 2009;54(5):1141-1143. View abstract.

Ramsay, T. G., Evock-Clover, C. M., Steele, N. C., and Azain, M. J. Dietary conjugated linoleic acid alters fatty acid composition of pig skeletal muscle and fat. J Anim Sci 2001;79(8):2152-2161. View abstract.

Rasooly, R., Kelley, D. S., Greg, J., and Mackey, B. E. Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Br.J Nutr 2007;97(1):58-66. View abstract.

Rayalam, S., Della-Fera, M. A., and Baile, C. A. Phytochemicals and regulation of the adipocyte life cycle. J Nutr Biochem. 2008;19(11):717-726. View abstract.

Rego, O. A., Regalo, S. M., Rosa, H. J., Alves, S. P., Borba, A. E., Bessa, R. J., Cabrita, A. R., and Fonseca, A. J. Effects of grass silage and soybean meal supplementation on milk production and milk fatty acid profiles of grazing dairy cows. J Dairy Sci 2008;91(7):2736-2743. View abstract.

Renaville, B., Mullen, A., Moloney, F., Larondelle, Y., Schneider, Y. J., and Roche, H. M. Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. Br J Nutr 2006;95(4):688-695. View abstract.

Renna, M., Collomb, M., Munger, A., and Wyss, U. Influence of low-level supplementation of grazing dairy cows with cereals or sugar beet pulp on the concentrations of CLA isomers in milk. J Sci Food Agric. 2010;90(7):1256-1267. View abstract.

Reynolds, C. M. and Roche, H. M. Conjugated linoleic acid and inflammatory cell signalling. Prostaglandins Leukot.Essent.Fatty Acids 2010;82(4-6):199-204. View abstract.

雷诺兹,c . M。德雷伯E,基奥,B。,拉赫曼。, Moloney, A. P., Mills, K. H., Loscher, C. E., and Roche, H. M. A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4. J Nutr 2009;139(12):2351-2357. View abstract.

Reynolds, C. M., Loscher, C. E., Moloney, A. P., and Roche, H. M. Cis-9, trans-11-conjugated linoleic acid but not its precursor trans-vaccenic acid attenuate inflammatory markers in the human colonic epithelial cell line Caco-2. Br.J Nutr 2008;100(1):13-17. View abstract.

Reza, J. Z., Doosti, M., Salehipour, M., Packnejad, M., Mojarrad, M., and Heidari, M. Modulation peroxisome proliferators activated receptor alpha (PPAR alpha) and acyl coenzyme A: cholesterol acyltransferase1 (ACAT1) gene expression by fatty acids in foam cell. Lipids Health Dis. 2009;8:38. View abstract.

Ribeiro, C. V., Eastridge, M. L., Firkins, J. L., St Pierre, N. R., and Palmquist, D. L. Kinetics of fatty acid biohydrogenation in vitro. J Dairy Sci 2007;90(3):1405-1416. View abstract.

Ribot, J., Portillo, M. P., Pico, C., Macarulla, M. T., and Palou, A. Effects of trans-10, cis-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet. Br.J Nutr 2007;97(6):1074-1082. View abstract.

Rigano, L., Andolfatto, C., Bonfigli, A., and Rastrelli, F. CLA Glutathione and Sodium DNA for Reducing Hair Loss. Cosmetics & Toiletries 2007;122(10):71-80.

Ringseis, R. and Eder, K. Influence of conjugated linoleic acids on functional properties of vascular cells. Br.J Nutr 2009;102(8):1099-1116. View abstract.

Ringseis, R., Gahler, S., and Eder, K. Conjugated linoleic acid isomers inhibit platelet-derived growth factor-induced NF-kappaB transactivation and collagen formation in human vascular smooth muscle cells. Eur J Nutr 2008;47(2):59-67. View abstract.

Ringseis, R., Muller, A., Dusterloh, K., Schleser, S., Eder, K., and Steinhart, H. Formation of conjugated linoleic acid metabolites in human vascular endothelial cells. Biochim.Biophys Acta 2006;1761(3):377-383. View abstract.

Ringseis, R., Muschick, A., and Eder, K. Dietary oxidized fat prevents ethanol-induced triacylglycerol accumulation and increases expression of PPARalpha target genes in rat liver. J Nutr 2007;137(1):77-83. View abstract.

Ringseis, R., Schulz, N., Saal, D., and Eder, K. Troglitazone but not conjugated linoleic acid reduces gene expression and activity of matrix-metalloproteinases-2 and -9 in PMA-differentiated THP-1 macrophages. J Nutr Biochem. 2008;19(9):594-603. View abstract.

Ringseis, R., Wen, G., Saal, D., and Eder, K. Conjugated linoleic acid isomers reduce cholesterol accumulation in acetylated LDL-induced mouse RAW264.7 macrophage-derived foam cells. Lipids 2008;43(10):913-923. View abstract.

Riserus, U., Basu, S., Jovinge, S., Fredrikson, G. N., Arnlov, J., and Vessby, B. Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Circulation 10-8-2002;106(15):1925-1929. View abstract.

Riserus, U., Berglund, L., and Vessby, B. Conjugated linoleic acid (CLA) reduced abdominal adipose tissue in obese middle-aged men with signs of the metabolic syndrome: a randomised controlled trial. Int J Obes.Relat Metab Disord 2001;25(8):1129-1135. View abstract.

Riserus, U., Vessby, B., Arnlov, J., and Basu, S. Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. Am J Clin Nutr 2004;80(2):279-283. View abstract.

Ritzenthaler, K. L., McGuire, M. K., Falen, R., Shultz, T. D., Dasgupta, N., and McGuire, M. A. Estimation of conjugated linoleic acid intake by written dietary assessment methodologies underestimates actual intake evaluated by food duplicate methodology. J Nutr 2001;131(5):1548-1554. View abstract.

Rocha-Uribe, A. Hernandez E. Effect of Conjugated Linoleic Acid and Fatty Acid Positional Distribution on Physicochemical Properties of Structured Lipids. Journal of the American Oil Chemists' Society 2008;85(11):997-1004.

Roche, H. M., Terres, A. M., Black, I. B., Gibney, M. J., and Kelleher, D. Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells. Gut 2001;48(6):797-802. View abstract.

Rodriguez-Alcala, L. M. and Fontecha, J. Hot topic: Fatty acid and conjugated linoleic acid (CLA) isomer composition of commercial CLA-fortified dairy products: evaluation after processing and storage. J Dairy Sci 2007;90(5):2083-2090. View abstract.

Roman, J. L., Gonzalvez, A. B. M., Luque, A., Iglesias, J. R., Hernandez, M., and Villegas, J. A. Physical activity and milk intake with conjugated linoleic acid (CLA) in healthy people with excess weight. Revista Espanola de Obesidad 2007;5(2):109-118.

Roman-Nunez, M., Cuesta-Alonso, E. P., and Gilliland, S. E. Influence of sodium glycocholate on production of conjugated linoleic acid by cells of Lactobacillus reuteri ATCC 55739. J Food Sci 2007;72(4):M140-M143. View abstract.

Rosberg-Cody, E., Johnson, M. C., Fitzgerald, G. F., Ross, P. R., and Stanton, C. Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid. Microbiology 2007;153(Pt 8):2483-2490. View abstract.

Rosberg-Cody, E., Ross, R. P., Hussey, S., Ryan, C. A., Murphy, B. P., Fitzgerald, G. F., Devery, R., and Stanton, C. Mining the microbiota of the neonatal gastrointestinal tract for conjugated linoleic acid-producing bifidobacteria. Appl Environ.Microbiol. 2004;70(8):4635-4641. View abstract.

Rossary, A., Arab, K., and Steghens, J. P. Polyunsaturated fatty acids modulate NOX 4 anion superoxide production in human fibroblasts. Biochem.J 8-15-2007;406(1):77-83. View abstract.

Rowe, C. W., Pohlman, F. W., Brown, A. H., Jr., Johnson, Z. B., Whiting, S. H., and Galloway, D. L. Effects of conjugated linoleic acid, salt, and sodium tripolyphosphate on physical, sensory, and instrumental color characteristics of beef striploins. J Food Sci 2009;74(1):S36-S43. View abstract.

Roy, B. D., Bourgeois, J., Rodriguez, C., Payne, E., Young, K., Shaughnessy, S. G., and Tarnopolosky, M. A. Conjugated linoleic acid prevents growth attenuation induced by corticosteroid administration and increases bone mineral content in young rats. Appl.Physiol Nutr Metab 2008;33(6):1096-1104. View abstract.

Ruiz-Rodriguez, Reglero, G。,和Ibanez说,e .再保险cent trends in the advanced analysis of bioactive fatty acids. J Pharm.Biomed.Anal. 1-20-2010;51(2):305-326. View abstract.

Russell, J. S., McGee, S. O., Ip, M. M., Kuhlmann, D., and Masso-Welch, P. A. Conjugated linoleic acid induces mast cell recruitment during mouse mammary gland stromal remodeling. J Nutr 2007;137(5):1200-1207. View abstract.

Ruth, M. R., Taylor, C. G., Zahradka, P., and Field, C. J. Abnormal immune responses in fa/fa Zucker rats and effects of feeding conjugated linoleic acid. Obesity.(Silver.Spring) 2008;16(8):1770-1779. View abstract.

Ryder, J. W., Portocarrero, C. P., Song, X. M., Cui, L., Yu, M., Combatsiaris, T., Galuska, D., Bauman, D. E., Barbano, D. M., Charron, M. J., Zierath, J. R., and Houseknecht, K. L. Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression. Diabetes 2001;50(5):1149-1157. View abstract.

Sagwal, R. and Kansal, V. K. Synergistic effect of synthetic conjugated linoleic acid & non fat milk on fat deposition & lipid metabolism in mice. Indian J Med Res 2010;131:449-454. View abstract.

Sakono, M., Miyanaga, F., Kawahara, S., Yamauchi, K., Fukuda, N., Watanabe, K., Iwata, T., and Sugano, M. Dietary conjugated linoleic acid reciprocally modifies ketogenesis and lipid secretion by the rat liver. Lipids 1999;34(9):997-1000. View abstract.

Sakuma, S., Nishioka, Y., Imanishi, R., Nishikawa, K., Sakamoto, H., Fujisawa, J., Wada, K., Kamisaki, Y., and Fujimoto, Y. cis9, trans11-Conjugated Linoleic Acid Differentiates Mouse 3T3-L1 Preadipocytes into Mature Small Adipocytes through Induction of Peroxisome Proliferator-activated Receptor gamma. J Clin.Biochem.Nutr 2010;47(2):167-173. View abstract.

Salas-Salvado, J., Marquez-Sandoval, F., and Bullo, M. Conjugated linoleic acid intake in humans: a systematic review focusing on its effect on body composition, glucose, and lipid metabolism. Crit Rev.Food Sci.Nutr. 2006;46(6):479-488. View abstract.

Salva, B. K., Zumalacarregui, J. M., Figueira, A. C., Osorio, M. T., and Mateo, J. Nutrient composition and technological quality of meat from alpacas reared in Peru. Meat.Sci 2-28-2009; View abstract.

Santercole, V., Mazzette, R., De Santis, E. P., Banni, S., Goonewardene, L., and Kramer, J. K. Total lipids of Sarda sheep meat that include the fatty acid and alkenyl composition and the CLA and trans-18:1 isomers. Lipids 2007;42(4):361-382. View abstract.

Santillo, A., Albenzio, M., Quinto, M., Caroprese, M., Marino, R., and Sevi, A. Probiotic in lamb rennet paste enhances rennet lipolytic activity, and conjugated linoleic acid and linoleic acid content in Pecorino cheese. J Dairy Sci 2009;92(4):1330-1337. View abstract.

Santillo, A., Quinto, M., Dentico, M., Muscio, A., Sevi, A., and Albenzio, M. Rennet paste from lambs fed a milk substitute supplemented with Lactobacillus acidophilus: effects on lipolysis in ovine cheese. J Dairy Sci 2007;90(7):3134-3142. View abstract.

Santora, J. E., Palmquist, D. L., and Roehrig, K. L. Trans-vaccenic acid is desaturated to conjugated linoleic acid in mice. J Nutr 2000;130(2):208-215. View abstract.

Santos-Zago, L. F., Botelho, A. P., and de Oliveira, A. C. Supplementation with commercial mixtures of conjugated linoleic acid in association with vitamin E and the process of lipid autoxidation in rats. Lipids 2007;42(9):845-854. View abstract.

Sasikala-Appukuttan, A. K., Schingoethe, D. J., Hippen, A. R., Kalscheur, K. F., Karges, K., and Gibson, M. L. The feeding value of corn distillers solubles for lactating dairy cows. J Dairy Sci 2008;91(1):279-287. View abstract.

Sauer, L. A., Blask, D. E., and Dauchy, R. T. Dietary factors and growth and metabolism in experimental tumors. J Nutr Biochem. 2007;18(10):637-649. View abstract.

Scatliff, C. E., Bankovic-Calic, N., Ogborn, M. R., and Aukema, H. M. Effects of dietary conjugated linoleic acid in advanced experimental polycystic kidney disease. Nephron Exp.Nephrol. 2008;110(2):e44-e48. View abstract.

Schennink, A., Heck, J. M., Bovenhuis, H., Visker, M. H., van Valenberg, H. J., and van Arendonk, J. A. Milk fatty acid unsaturation: genetic parameters and effects of stearoyl-CoA desaturase (SCD1) and acyl CoA: diacylglycerol acyltransferase 1 (DGAT1). J Dairy Sci 2008;91(5):2135-2143. View abstract.

Schennink, A., Stoop, W. M., Visker, M. H., Heck, J. M., Bovenhuis, H., van der Poel, J. J., van Valenberg, H. J., and van Arendonk, J. A. DGAT1 underlies large genetic variation in milk-fat composition of dairy cows. Anim Genet. 2007;38(5):467-473. View abstract.

Schiavon, S., Tagliapietra, F., Dal Maso, M., Bailoni, L., and Bittante, G. Effects of low-protein diets and rumen-protected conjugated linoleic acid on production and carcass traits of growing double-muscled Piemontese bulls. J Anim Sci 2010;88(10):3372-3383. View abstract.

Schievano, E., Pasini, G., Cozzi, G., and Mammi, S. Identification of the production chain of Asiago d'Allevo cheese by nuclear magnetic resonance spectroscopy and principal component analysis. J Agric.Food Chem. 8-27-2008;56(16):7208-7214. View abstract.

Schmid, A., Collomb, M., Bee, G., Butikofer, U., Wechsler, D., Eberhard, P., and Sieber, R. Effect of dietary alpine butter rich in conjugated linoleic acid on milk fat composition of lactating sows. Br.J Nutr 2008;100(1):54-60. View abstract.

Schoeller, D. A., Watras, A. C., and Whigham, L. D. A meta-analysis of the effects of conjugated linoleic acid on fat-free mass in humans. Appl.Physiol Nutr Metab 2009;34(5):975-978. View abstract.

Schripsema, J. Comprehensive analysis of polar and apolar constituents of butter and margarine by nuclear magnetic resonance, reflecting quality and production processes. J Agric.Food Chem. 4-23-2008;56(8):2547-2552. View abstract.

Schut, h·a .和祖茂堂h . 32 p - x应用程序postlabelling assay to the inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA adduct formation by dietary fatty acids. IARC Sci Publ. 1993;(124):181-188. View abstract.

Serini, S., Piccioni, E., Merendino, N., and Calviello, G. Dietary polyunsaturated fatty acids as inducers of apoptosis: implications for cancer. Apoptosis. 2009;14(2):135-152. View abstract.

Shadman, Z., Rastmanesh, R., Hedayati, M., Taleban, F. A., Saadat, N., Tahbaz, F., and Mehrabi, Y. Effects of conjugated linoleic acid on insulin sensitivity and diabetes markers in type 2 diabetic patients. Iranian Journal of Endocrinology & Metabolism 2009;11(2):221.

Shahin, A. M., McGuire, M. K., Anderson, N., Williams, J., and McGuire, M. A. Effects of margarine and butter consumption on distribution of trans-18:1 fatty acid isomers and conjugated linoleic acid in major serum lipid classes in lactating women. Lipids 2006;41(2):141-147. View abstract.

Shen, X., Nuernberg, K., Nuernberg, G., Zhao, R., Scollan, N., Ender, K., and Dannenberger, D. Vaccenic acid and cis-9,trans-11 CLA in the rumen and different tissues of pasture- and concentrate-fed beef cattle. Lipids 2007;42(12):1093-1103. View abstract.

Sher, J., Pronczuk, A., Hajri, T., and Hayes, K. C. Dietary conjugated linoleic acid lowers plasma cholesterol during cholesterol supplementation, but accentuates the atherogenic lipid profile during the acute phase response in hamsters. J Nutr 2003;133(2):456-460. View abstract.

Shingfield, K. J., Ahvenjarvi, S., Toivonen, V., Vanhatalo, A., and Huhtanen, P. Transfer of absorbed cis-9, trans-11 conjugated linoleic acid into milk is biologically more efficient than endogenous synthesis from absorbed vaccenic acid in lactating cows. J Nutr 2007;137(5):1154-1160. View abstract.

Shingfield, K. J., Ahvenjarvi, S., Toivonen, V., Vanhatalo, A., Huhtanen, P., and Griinari, J. M. Effect of incremental levels of sunflower-seed oil in the diet on ruminal lipid metabolism in lactating cows. Br.J Nutr 2008;99(5):971-983. View abstract.

Shingfield, K. J., Rouel, J., and Chilliard, Y. Effect of calcium salts of a mixture of conjugated linoleic acids containing trans-10, cis-12 in the diet on milk fat synthesis in goats. Br.J Nutr 2009;101(7):1006-1019. View abstract.

Shingfield, K. J., Saebo, A., Saebo, P. C., Toivonen, V., and Griinari, J. M. Effect of abomasal infusions of a mixture of octadecenoic acids on milk fat synthesis in lactating cows. J Dairy Sci 2009;92(9):4317-4329. View abstract.

Shiraishi, R., Iwakiri, R., Fujise, T., Kuroki, T., Kakimoto, T., Takashima, T., Sakata, Y., Tsunada, S., Nakashima, Y., Yanagita, T., and Fujimoto, K. Conjugated linoleic acid suppresses colon carcinogenesis in azoxymethane-pretreated rats with long-term feeding of diet containing beef tallow. J Gastroenterol. 2010;45(6):625-635. View abstract.

Shiraki, T. [Activation mechanism of PPARgamma by its endogenous ligands]. Seikagaku 2007;79(10):960-964. View abstract.

Shultz, T. D., Chew, B. P., and Seaman, W. R. Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture. Anticancer Res 1992;12(6B):2143-2145. View abstract.

Shultz, T. D., Chew, B. P., Seaman, W. R., and Luedecke, L. O. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. Cancer Lett 4-15-1992;63(2):125-133. View abstract.

Siddiqui, R., Pandya, D., Harvey, K., and Zaloga, G. P. Nutrition modulation of cachexia/proteolysis. Nutr Clin Pract. 2006;21(2):155-167. View abstract.

Sikorski, A. M., Hebert, N., and Swain, R. A. Conjugated Linoleic Acid (CLA) inhibits new vessel growth in the mammalian brain. Brain Res 6-5-2008;1213:35-40. View abstract.

Silberberg, Y. R., Yakubov, G. E., Horton, M. A., and Pelling, A. E. Cell nanomechanics and focal adhesions are regulated by retinol and conjugated linoleic acid in a dose-dependent manner. Nanotechnology. 7-15-2009;20(28):285103. View abstract.

Silveira, M. B., Carraro, R., Monereo, S., and Tebar, J. Conjugated linoleic acid (CLA) and obesity. Public Health Nutr 2007;10(10A):1181-1186. View abstract.

Sinclair, L. A., Lock, A. L., Early, R., and Bauman, D. E. Effects of trans-10, cis-12 conjugated linoleic acid on ovine milk fat synthesis and cheese properties. J Dairy Sci 2007;90(7):3326-3335. View abstract.

Sisk, M. B., Hausman, D. B., Martin, R. J., and Azain, M. J. Dietary conjugated linoleic acid reduces adiposity in lean but not obese Zucker rats. J Nutr 2001;131(6):1668-1674. View abstract.

Sluijs, I., Plantinga, Y., de Roos, B., Mennen, L. I., and Bots, M. L. Dietary supplementation with cis-9,trans-11 conjugated linoleic acid and aortic stiffness in overweight and obese adults. Am.J Clin.Nutr 2010;91(1):175-183. View abstract.

Smedman, A., Basu, S., Jovinge, S., Fredrikson, G. N., and Vessby, B. Conjugated linoleic acid increased C-reactive protein in human subjects. Br J Nutr 2005;94(5):791-795. View abstract.

Smedman, A., Vessby, B., and Basu, S. Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitor. Clin Sci (Lond) 2004;106(1):67-73. View abstract.

Smit, L. A., Baylin, A., and Campos, H. Conjugated linoleic acid in adipose tissue and risk of myocardial infarction. Am.J Clin.Nutr 2010;92(1):34-40. View abstract.

Smit, L. A., Willett, W. C., and Campos, H. trans-fatty acid isomers in adipose tissue have divergent associations with adiposity in humans. Lipids 2010;45(8):693-700. View abstract.

Sneddon, A. A., Tsofliou, F., Fyfe, C. L., Matheson, I., Jackson, D. M., Horgan, G., Winzell, M. S., Wahle, K. W., Ahren, B., and Williams, L. M. Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin. Obesity.(Silver.Spring) 2008;16(5):1019-1024. View abstract.

Sneddon, A. A., Wu, H. C., Farquharson, A., Grant, I., Arthur, J. R., Rotondo, D., Choe, S. N., and Wahle, K. W. Regulation of selenoprotein GPx4 expression and activity in human endothelial cells by fatty acids, cytokines and antioxidants. Atherosclerosis 2003;171(1):57-65. View abstract.

So, M. H., Tse, I. M., and Li, E. T. Dietary fat concentration influences the effects of trans-10, cis-12 conjugated linoleic acid on temporal patterns of energy intake and hypothalamic expression of appetite-controlling genes in mice. J Nutr 2009;139(1):145-151. View abstract.

Soel, S. M., Choi, O. S., Bang, M. H., Yoon Park, J. H., and Kim, W. K. Influence of conjugated linoleic acid isomers on the metastasis of colon cancer cells in vitro and in vivo. J Nutr Biochem. 2007;18(10):650-657. View abstract.

Sofi, F., Buccioni, A., Cesari, F., Gori, A. M., Minieri, S., Mannini, L., Casini, A., Gensini, G. F., Abbate, R., and Antongiovanni, M. Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inflammatory and haemorheological variables: a dietary intervention study. Nutr Metab Cardiovasc.Dis. 2010;20(2):117-124. View abstract.

Song, D. H., Kang, J. H., Lee, G. S., Jeung, E. B., and Yang, M. P. Upregulation of tumor necrosis factor-alpha expression by trans10-cis12 conjugated linoleic acid enhances phagocytosis of RAW macrophages via a peroxisome proliferator-activated receptor gamma-dependent pathway. Cytokine 2007;37(3):227-235. View abstract.

Song, H. J., Sneddon, A. A., Barker, P. A., Bestwick, C., Choe, S. N., McClinton, S., Grant, I., Rotondo, D., Heys, S. D., and Wahle, K. W. Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells. Nutr Cancer 2004;49(1):100-108. View abstract.

Song, H. J., Sneddon, A. A., Heys, S. D., and Wahle, K. W. Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid. Prostate 6-1-2006;66(8):839-846. View abstract.

Song, M. K., Jin, G. L., Ji, B. J., Chang, S. S., Jeong, J., Smith, S. B., and Choi, S. H. Conjugated linoleic acids content in M.longissimus dorsi of Hanwoo steers fed a concentrate supplemented with soybean oil, sodium bicarbonate-based monensin, fish oil. Meat.Sci 2010;85(2):210-214. View abstract.

Sorensen, B. M., Chris, Kazala E., Murdoch, G. K., Keating, A. F., Cruz-Hernandez, C., Wegner, J., Kennelly, J. J., Okine, E. K., and Weselake, R. J. Effect of CLA and other C18 unsaturated fatty acids on DGAT in bovine milk fat biosynthetic systems. Lipids 2008;43(10):903-912. View abstract.

Soulard, P., McLaughlin, M., Stevens, J., Connolly, B., Coli, R., Wang, L., Moore, J., Kuo, M. S., LaMarr, W. A., Ozbal, C. C., and Bhat, B. G. Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry. Anal.Chim.Acta 10-3-2008;627(1):105-111. View abstract.

Soveral, G., Martins, A. P., Martins, S. V., Lopes, P. A., Alfaia, C. M., Prates, J. A., and Moura, T. F. Effect of dietary conjugated linoleic acid isomers on water and glycerol permeability of kidney membranes. Biochem.Biophys.Res Commun. 5-22-2009;383(1):108-112. View abstract.

Soyeurt, H. and Gengler, N. Genetic variability of fatty acids in bovine milk. Biotechnologie, Agronomie, Societe et Environnement 2008;12(2):203-210.

Stachowska, E. Conjugated dienes of linoleic acid and tumorigenesis. Ann.Acad.Med Stetin. 2008;54(3):122-125. View abstract.

Stachowska, E., Baskiewicz, M., Marchlewicz, M., Czuprynska, K., Kaczmarczyk, M., Wiszniewska, B., Machalinski, B., and Chlubek, D. Conjugated linoleic acids regulate triacylglycerol and cholesterol concentrations in macrophages/foam cells by the modulation of CD36 expression. Acta Biochim.Pol. 2010;57(3):379-384. View abstract.

Stachowska, E., Baskiewicz-Masiuk, M., Dziedziejko, V., Adler, G., Bober, J., Machalinski, B., and Chlubek, D. Conjugated linoleic acids can change phagocytosis of human monocytes/macrophages by reduction in Cox-2 expression. Lipids 2007;42(8):707-716. View abstract.

Stachowska, E., Baskiewicz-Masiuk, M., Dziedziejko, V., Gutowska, I., Baranowska-Bosiacka, I., Marchlewicz, M., Dolegowska, B., Wiszniewska, B., Machalinski, B., and Chlubek, D. Conjugated linoleic acid increases intracellular ROS synthesis and oxygenation of arachidonic acid in macrophages. Nutrition 2008;24(2):187-199. View abstract.

Stachowska, E., Dolegowska, B., Dziedziejko, V., Rybicka, M., Kaczmarczyk, M., Bober, J., Rac, M., Machalinski, B., and Chlubek, D. Prostaglandin E2 (PGE2) and thromboxane A2 (TXA2) synthesis is regulated by conjugated linoleic acids (CLA) in human macrophages. J Physiol Pharmacol. 2009;60(1):77-85. View abstract.

Stachowska, E., Dziedziejko, V., Safranow, K., Gutowska, I., Adler, G., Ciechanowicz, A., Machalinski, B., and Chlubek, D. Inhibition of phospholipase A(2) activity by conjugated linoleic acids in human macrophages. Eur J Nutr 2007;46(1):28-33. View abstract.

Stachowska, E., Dziedziejko, V., Safranow, K., Jakubowska, K., Olszewska, M., Machalinski, B., and Chlubek, D. Effect of conjugated linoleic acids on the activity and mRNA expression of 5- and 15-lipoxygenases in human macrophages. J Agric.Food Chem. 6-27-2007;55(13):5335-5342. View abstract.

Stachowska, E., Gutowska, I., Szumilowicz, H., Bober, J., and Chlubek, D. Is conjugated linoleic acid (CLA) a protective factor in atherosclerosis? Study with the use of neural networks. Ann.Acad.Med Stetin. 2005;51(2):27-32. View abstract.

Stangl, G. I. High dietary levels of a conjugated linoleic acid mixture alter hepatic glycerophospholipid class profile and cholesterol-carrying serum lipoproteins of rats. J Nutr Biochem. 2000;11(4):184-191. View abstract.

Steck, S. E., Chalecki, A. M., Miller, P., Conway, J., Austin, G. L., Hardin, J. W., Albright, C. D., and Thuillier, P. Conjugated linoleic acid supplementation for twelve weeks increases lean body mass in obese humans. J Nutr 2007;137(5):1188-1193. View abstract.

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Stoop, W. M., Bovenhuis, H., Heck, J. M., and van Arendonk, J. A. Effect of lactation stage and energy status on milk fat composition of Holstein-Friesian cows. J Dairy Sci 2009;92(4):1469-1478. View abstract.

Storey, A., Rogers, J. S., McArdle, F., Jackson, M. J., and Rhodes, L. E. Conjugated linoleic acids modulate UVR-induced IL-8 and PGE2 in human skin cells: potential of CLA isomers in nutritional photoprotection. Carcinogenesis 2007;28(6):1329-1333. View abstract.

Stringer, D. M., Zahradka, P., Declercq, V. C., Ryz, N. R., Diakiw, R., Burr, L. L., Xie, X., and Taylor, C. G. Modulation of lipid droplet size and lipid droplet proteins by trans-10,cis-12 conjugated linoleic acid parallels improvements in hepatic steatosis in obese, insulin-resistant rats. Biochim.Biophys.Acta 2010;1801(12):1375-1385. View abstract.

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Sugano, M., Tsujita, A., Yamasaki, M., Noguchi, M., and Yamada, K. Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids 1998;33(5):521-527. View abstract.

Suksombat, W., Boonmee, T., and Lounglawan, P. Effects of various levels of conjugated linoleic acid supplementation on fatty acid content and carcass composition of broilers. Poult.Sci 2007;86(2):318-324. View abstract.

Syvertsen, C., Halse, J., Hoivik, H. O., Gaullier, J. M., Nurminiemi, M., Kristiansen, K., Einerhand, A., O'Shea, M., and Gudmundsen, O. The effect of 6 months supplementation with conjugated linoleic acid on insulin resistance in overweight and obese. Int.J.Obes.(Lond) 2007;31(7):1148-1154. View abstract.

Takahashi, K., Akiba, Y., Iwata, T., and Kasai, M. Effect of a mixture of conjugated linoleic acid isomers on growth performance and antibody production in broiler chicks. Br J Nutr 2003;89(5):691-694. View abstract.

Takahashi, Y., Kushiro, M., Shinohara, K., and Ide, T. Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid. Biochim.Biophys.Acta 4-8-2003;1631(3):265-273. View abstract.

Takahashi, Y., Kushiro, M., Shinohara, K., and Ide, T. Dietary conjugated linoleic acid reduces body fat mass and affects gene expression of proteins regulating energy metabolism in mice. Comp Biochem.Physiol B Biochem.Mol.Biol 2002;133(3):395-404. View abstract.

Tanmahasamut, P., Liu, J., Hendry, L. B., and Sidell, N. Conjugated linoleic acid blocks estrogen signaling in human breast cancer cells. J Nutr 2004;134(3):674-680. View abstract.

Tappia, P. S., Dent, M. R., Aroutiounova, N., Babick, A. P., and Weiler, H. Gender differences in the modulation of cardiac gene expression by dietary conjugated linoleic acid isomers. Can.J Physiol Pharmacol. 2007;85(3-4):465-475. View abstract.

Tarling, e·J。瑞安,k . J。班纳特,a·J。,alter, A. M. Effect of dietary conjugated linoleic acid isomers on lipid metabolism in hamsters fed high-carbohydrate and high-fat diets. Br.J Nutr 2009;101(11):1630-1638. View abstract.

Tarnopolsky, M., Zimmer, A., Paikin, J., Safdar, A., Aboud, A., Pearce, E., Roy, B., and Doherty, T. Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults. PLoS.One. 2007;2(10):e991. View abstract.

Taylor, J. S., Williams, S. R., Rhys, R., James, P., and Frenneaux, M. P. Conjugated linoleic acid impairs endothelial function. Arterioscler.Thromb.Vasc.Biol 2006;26(2):307-312. View abstract.

Terpstra, a . H。Javadi, M, Beynen, a·C。柯奇士便因, S., Lankhorst, A. E., Lemmens, A. G., and Mohede, I. C. Dietary conjugated linoleic acids as free fatty acids and triacylglycerols similarly affect body composition and energy balance in mice. J Nutr 2003;133(10):3181-3186. View abstract.

Thatcher, W., Santos, J. E., Silvestre, F., Kim, L., and Staples, C. Perspective on Physiological/Endocrine and Nutritional Factors Influencing Fertility in Post-partum Dairy Cows. Reproduction in Domestic Animals 2010;45:2-14.

Theurer, M. L., Block, E., Sanchez, W. K., and McGuire, M. A. Calcium salts of polyunsaturated fatty acids deliver more essential fatty acids to the lactating dairy cow. J Dairy Sci 2009;92(5):2051-2056. View abstract.

Tholstrup, T., Raff, M., Straarup, E. M., Lund, P., Basu, S., and Bruun, J. M. An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women. J Nutr 2008;138(8):1445-1451. View abstract.

Thrush, A. B., Chabowski, A., Heigenhauser, G. J., McBride, B. W., Or-Rashid, M., and Dyck, D. J. Conjugated linoleic acid increases skeletal muscle ceramide content and decreases insulin sensitivity in overweight, non-diabetic humans. Appl.Physiol Nutr Metab 2007;32(3):372-382. View abstract.

Tischendorf, F。,Mockel, P Schone, F。,Plonne, M。, and Jahreis, G. Effect of dietary conjugated linoleic acids on the distribution of fatty acids in serum lipoprotein fractions and different tissues of growing pigs. J Anim Physiol Anim Nutr (Berl) 2002;86(9-10):313-325. View abstract.

Toke, N., Nagy, V., Recseg, K., Szakacs, G., and Poppe, L. Production and Application of Novel Sterol Esterases from Aspergillus Strains by Solid State Fermentation. JAOCS: Journal of the American Oil Chemists' Society 2007;84(10):3.

Tokle, T., Jain, V. P., and Proctor, A. Effect of minor oil constituents on soy oil conjugated linoleic acid production. J Agric.Food Chem. 10-14-2009;57(19):8989-8997. View abstract.

Toomey, S., Roche, H., Fitzgerald, D., and Belton, O. Regression of pre-established atherosclerosis in the apoE-/- mouse by conjugated linoleic acid. Biochem Soc Trans 2003;31(Pt 5):1075-1079. View abstract.

Toral, P. G., Frutos, P., Hervas, G., Gomez-Cortes, P., Juarez, M., and De la Fuente, M. A. Changes in milk fatty acid profile and animal performance in response to fish oil supplementation, alone or in combination with sunflower oil, in dairy ewes. J Dairy Sci 2010;93(4):1604-1615. View abstract.

Toral, P. G., Shingfield, K. J., Hervas, G., Toivonen, V., and Frutos, P. Effect of fish oil and sunflower oil on rumen fermentation characteristics and fatty acid composition of digesta in ewes fed a high concentrate diet. J Dairy Sci 2010;93(10):4804-4817. View abstract.

Torres, A. G., Ney, J. G., Meneses, F., and Trugo, N. M. Polyunsaturated fatty acids and conjugated linoleic acid isomers in breast milk are associated with plasma non-esterified and erythrocyte membrane fatty acid composition in lactating women. Br J Nutr 2006;95(3):517-524. View abstract.

Torres, C. F., Torrelo, G., Vazquez, L., Senorans, F. J., and Reglero, G. Stepwise esterification of phytosterols with conjugated linoleic acid catalyzed by Candida rugosa lipase in solvent-free medium. J Biosci.Bioeng. 2008;106(6):559-562. View abstract.

Torres, C. F., Vasquez, L., Senorans, F. J., and Reglero, G. An Efficient Methodology for the Preparation of Alkoxyglycerols Rich in Conjugated Linoleic Acid and Eicosapentaenoic Acid. JAOCS: Journal of the American Oil Chemists' Society 2007;84(5):443-448.

Torres-Duarte, A. P. and Vanderhoek, J. Y. Conjugated linoleic acid exhibits stimulatory and inhibitory effects on prostanoid production in human endothelial cells and platelets. Biochim.Biophys Acta 4-7-2003;1640(1):69-76. View abstract.

Tricon, S. and Yaqoob, P. Conjugated linoleic acid and human health: a critical evaluation of the evidence. Curr Opin Clin Nutr Metab Care 2006;9(2):105-110. View abstract.

Tricon, S., Burdge, G. C., Kew, S., Banerjee, T., Russell, J. J., Grimble, R. F., Williams, C. M., Calder, P. C., and Yaqoob, P. Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on immune cell function in healthy humans. Am J Clin Nutr 2004;80(6):1626-1633. View abstract.

Tricon, S., Burdge, G. C., Kew, S., Banerjee, T., Russell, J. J., Jones, E. L., Grimble, R. F., Williams, C. M., Yaqoob, P., and Calder, P. C. Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans. Am J Clin Nutr 2004;80(3):614-620. View abstract.

Troegeler-Meynadier, A., Nicot, M. C., and Enjalbert, F. Effects of fat source and dietary sodium bicarbonate plus straw on the conjugated linoleic acid content of milk of dairy cows. Arch.Anim Nutr 2007;61(5):406-415. View abstract.

Truitt, A., McNeill, G., and Vanderhoek, J. Y. Antiplatelet effects of conjugated linoleic acid isomers. Biochim.Biophys.Acta 5-18-1999;1438(2):239-246. View abstract.

Tsiplakou, E. and Zervas, G. The effect of dietary inclusion of olive tree leaves and grape marc on the content of conjugated linoleic acid and vaccenic acid in the milk of dairy sheep and goats. J Dairy Res 2008;75(3):270-278. View abstract.

Tsiplakou, E., Flemetakis, E., Kalloniati, C., Papadomichelakis, G., Katinakis, P., and Zervas, G. Sheep and goats differences in CLA and fatty acids milk fat content in relation with mRNA stearoyl-CoA desaturase and lipogenic genes expression in their mammary gland. J Dairy Res 2009;76(4):392-401. View abstract.

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Tsuboyama-Kasaoka N,高桥,M, Tanemura, K。, Kim, H. J., Tange, T., Okuyama, H., Kasai, M., Ikemoto, S., and Ezaki, O. Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. Diabetes 2000;49(9):1534-1542. View abstract.

Tsuyama, S., Oikawa, D., Tsuji, Y., Akimoto, Y., Jikuya, H., and Furuse, M. Dietary conjugated linoleic acid modifies the brain endocannabinoid system in mice. Nutr Neurosci. 2009;12(4):155-159. View abstract.

Tsuzuki, T. and Ikeda, I. Slow absorption of conjugated linoleic acid in rat intestines, and similar absorption rates of 9c,11t-conjugated linoleic acid and 10t,12c-conjugated linoleic acid. Biosci.Biotechnol.Biochem. 2007;71(8):2034-2040. View abstract.

Turini, M. E., Boza, J. J., Gueissaz, N., Moennoz, D., Montigon, F., Vuichoud, J., Gremaud, G., Pouteau, E., Piguet, C., Perrin, I., Verguet, C., Finot, P. A., and German, B. Short-term dietary conjugated linoleic acid supplementation does not enhance the recovery of immunodepleted dexamethasone-treated rats. Eur.J Nutr 2003;42(3):171-179. View abstract.

Turnock, L., Cook, M., Steinberg, H., and Czuprynski, C. Dietary supplementation with conjugated linoleic acid does not alter the resistance of mice to Listeria monocytogenes infection. Lipids 2001;36(2):135-138. View abstract.

Turpeinen, A. M., Barlund, S., Freese, R., Lawrence, P., and Brenna, J. T. Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man. Br J Nutr 2006;95(4):727-733. View abstract.

Turpeinen, A. M., Mutanen, M., Aro, A., Salminen, I., Basu, S., Palmquist, D. L., and Griinari, J. M. Bioconversion of vaccenic acid to conjugated linoleic acid in humans. Am J Clin Nutr 2002;76(3):504-510. View abstract.

Turpeinen, A. M., Ylonen, N., von Willebrand, E., Basu, S., and Aro, A. Immunological and metabolic effects of cis-9, trans-11-conjugated linoleic acid in subjects with birch pollen allergy. Br.J Nutr 2008;100(1):112-119. View abstract.

Tyburczy, C., Lock, A. L., Dwyer, D. A., Destaillats, F., Mouloungui, Z., Candy, L., and Bauman, D. E. Uptake and utilization of trans octadecenoic acids in lactating dairy cows. J Dairy Sci 2008;91(10):3850-3861. View abstract.

Uehara, H., Suganuma, T., and Negishi, S. Physical Properties of Two Isomers of Conjugated Linoleic Acid. JAOCS: Journal of the American Oil Chemists' Society 2008;85(1):13.

Urquhart, P., Parkin, S. M., Rogers, J. S., Bosley, J. A., and Nicolaou, A. The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein endothelial cells. Biochim.Biophys.Acta 2-28-2002;1580(2-3):150-160. View abstract.

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Valeille, K., Ferezou, J., Amsler, G., Quignard-Boulange, A., Parquet, M., Gripois, D., Dorovska-Taran, V., and Martin, J. C. A cis-9,trans-11-conjugated linoleic acid-rich oil reduces the outcome of atherogenic process in hyperlipidemic hamster. Am J Physiol Heart Circ.Physiol 2005;289(2):H652-H659. View abstract.

Valeille, K., Gripois, D., Blouquit, M. F., Souidi, M., Riottot, M., Bouthegourd, J. C., Serougne, C., and Martin, J. C. Lipid atherogenic risk markers can be more favourably influenced by the cis-9,trans-11-octadecadienoate isomer than a conjugated linoleic acid mixture or fish oil in hamsters. Br J Nutr 2004;91(2):191-199. View abstract.

Valente, L. M., Bandarra, N. M., Figueiredo-Silva, A. C., Rema, P., Vaz-Pires, P., Martins, S., Prates, J. A., and Nunes, M. L. Conjugated linoleic acid in diets for large-size rainbow trout (Oncorhynchus mykiss): effects on growth, chemical composition and sensory attributes. Br.J Nutr 2007;97(2):289-297. View abstract.

van Dorland, H. A., Wettstein, H. R., Aeschlimann, G., Leuenberger, H., and Kreuzer, M. Preference of dairy cows for ryegrass, white clover and red clover, and its effects on nutrient supply and milk quality. Arch.Anim Nutr 2007;61(5):371-389. View abstract.

van Erk, M. J., Pasman, W. J., Wortelboer, H. M., van Ommen, B., and Hendriks, H. F. Short-term fatty acid intervention elicits differential gene expression responses in adipose tissue from lean and overweight men. Genes Nutr 2008;3(3-4):127-137. View abstract.

Van Nieuwenhove, C. P., Oliszewski, R., Gonzalez, S. N., and Perez Chaia, A. B. Conjugated linoleic acid conversion by dairy bacteria cultured in MRS broth and buffalo milk. Lett.Appl.Microbiol. 2007;44(5):467-474. View abstract.

Vasta, V., Makkar, H. P., Mele, M., and Priolo, A. Ruminal biohydrogenation as affected by tannins in vitro. Br.J Nutr 2009;102(1):82-92. View abstract.

Vasta, V., Mele, M., Serra, A., Scerra, M., Luciano, G., Lanza, M., and Priolo, A. Metabolic fate of fatty acids involved in ruminal biohydrogenation in sheep fed concentrate or herbage with or without tannins. J Anim Sci 2009;87(8):2674-2684. View abstract.

Veaute, C., Andreoli, M. F., Racca, A., Bailat, A., Scalerandi, M. V., Bernal, C., and Malan, Borel, I. Effects of isomeric fatty acids on reproductive parameters in mice. Am.J Reprod.Immunol. 2007;58(6):487-496. View abstract.

Venkatramanan, S., Joseph, S. V., Chouinard, P. Y., Jacques, H., Farnworth, E. R., and Jones, P. J. Milk enriched with conjugated linoleic Acid fails to alter blood lipids or body composition in moderately overweight, borderline hyperlipidemic individuals. J Am.Coll.Nutr 2010;29(2):152-159. View abstract.

Vikbjerg, A. F., Mu, H., and Xu, X. Synthesis of structured phospholipids by immobilized phospholipase A2 catalyzed acidolysis. J Biotechnol. 2-20-2007;128(3):545-554. View abstract.

Virtanen, S. M., Niinisto, S., Nevalainen, J., Salminen, I., Takkinen, H. M., Kaaria, S., Uusitalo, L., Alfthan, G., Kenward, M. G., Veijola, R., Simell, O., Ilonen, J., and Knip, M. Serum fatty acids and risk of advanced beta-cell autoimmunity: a nested case-control study among children with HLA-conferred susceptibility to type I diabetes. Eur J Clin.Nutr 2010;64(8):792-799. View abstract.

Visonneau, S., Cesano, A., Tepper, S. A., Scimeca, J. A., Santoli, D., and Kritchevsky, D. Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. Anticancer Res 1997;17(2A):969-973. View abstract.

Voorrips, L. E., Brants, H. A., Kardinaal, A. F., Hiddink, G. J., van den Brandt, P. A., and Goldbohm, R. A. Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer: the Netherlands Cohort Study on Diet and Cancer. Am J Clin Nutr 2002;76(4):873-882. View abstract.

Vu, P. L., Shin, J. A., Lee, Y. J., Nam, H. Y., Lee, J. H., Akoh, C. C., and Lee, K. T. Development and characterization of structured lipids containing capric and conjugated linoleic acids as functional dietary lipid molecules. Int J Food Sci Nutr 2008;59(2):95-104. View abstract.

Wall, R., Ross, R. P., Shanahan, F., O'Mahony, L., O'Mahony, C., Coakley, M., Hart, O., Lawlor, P., Quigley, E. M., Kiely, B., Fitzgerald, G. F., and Stanton, C. Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues. Am.J Clin.Nutr 2009;89(5):1393-1401. View abstract.

Wallace, R. J., McKain, N., Shingfield, K. J., and Devillard, E. Isomers of conjugated linoleic acids are synthesized via different mechanisms in ruminal digesta and bacteria. J Lipid Res 2007;48(10):2247-2254. View abstract.

Walters, J. M., Hackett, T. B., Ogilvie, G. K., and Fettman, M. J. Polyunsaturated Fatty Acid dietary supplementation induces lipid peroxidation in normal dogs. Vet.Med Int 2010;2010:619083. View abstract.

Wanders, A. J., Brouwer, I. A., Siebelink, E., and Katan, M. B. Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects. PLoS.One. 2010;5(2):e9000. View abstract.

Wanders, A. J., Leder, L., Banga, J. D., Katan, M. B., and Brouwer, I. A. A high intake of conjugated linoleic acid does not affect liver and kidney function tests in healthy human subjects. Food Chem.Toxicol. 2010;48(2):587-590. View abstract.

Wang, L. S., Huang, Y. W., Liu, S., Chang, H. L., Ye, W., Shu, S., Sugimoto, Y., Funk, J. A., Smeaks, D. D., Hill, L. N., and Lin, Y. C. Conjugated linoleic acid (CLA) modulates prostaglandin E2 (PGE2) signaling in canine mammary cells. Anticancer Res 2006;26(2A):889-898. View abstract.

Wang, L. S., Huang, Y. W., Liu, S., Yan, P., and Lin, Y. C. Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. BMC.Cancer 2008;8:208. View abstract.

Wang, L. S., Huang, Y. W., Sugimoto, Y., Liu, S., Chang, H. L., Ye, W., Shu, S., and Lin, Y. C. Conjugated linoleic acid (CLA) up-regulates the estrogen-regulated cancer suppressor gene, protein tyrosine phosphatase gamma (PTPgama), in human breast cells. Anticancer Res 2006;26(1A):27-34. View abstract.

Wang, L. S., Huang, Y. W., Sugimoto, Y., Liu, S., Chang, H. L., Ye, W., Shu, S., and Lin, Y. C. Effects of human breast stromal cells on conjugated linoleic acid (CLA) modulated vascular endothelial growth factor-A (VEGF-A) expression in MCF-7 cells. Anticancer Res 2005;25(6B):4061-4068. View abstract.

Wang, Y., Lu, J., Ruth, M. R., Goruk, S. D., Reaney, M. J., Glimm, D. R., Vine, D. F., Field, C. J., and Proctor, S. D. Trans-11 vaccenic acid dietary supplementation induces hypolipidemic effects in JCR:LA-cp rats. J Nutr 2008;138(11):2117-2122. View abstract.

Watkins, B. A., Devitt, A. A., and Feng, S. Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. World Rev Nutr Diet. 2001;90:162-182. View abstract.

Watras, A. C., Buchholz, A. C., Close, R. N., Zhang, Z., and Schoeller, D. A. The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain. Int.J.Obes.(Lond) 2007;31(3):481-487. View abstract.

魏,M,崔、W。雪,z [bioconv动力学ersion of linoleic acid to conjugated linoleic acid by permeabilized Lactobacillus acidophilus cells]. Sheng Wu Gong.Cheng Xue.Bao. 2010;26(4):503-508. View abstract.

Weiler, H. A., Fitzpatrick, S., and Fitzpatrick-Wong, S. C. Dietary conjugated linoleic acid in the cis-9, trans-11 isoform reduces parathyroid hormone in male, but not female, rats. J Nutr Biochem. 2008;19(11):762-769. View abstract.

Weldon, S., Mitchell, S., Kelleher, D., Gibney, M. J., and Roche, H. M. Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages. Atherosclerosis 2004;174(2):261-273. View abstract.

Wendel, A. A., Purushotham, A., Liu, L. F., and Belury, M. A. Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice. J Lipid Res 2008;49(1):98-106. View abstract.

Wendel, A. A., Purushotham, A., Liu, L. F., and Belury, M. A. Conjugated linoleic acid induces uncoupling protein 1 in white adipose tissue of ob/ob mice. Lipids 2009;44(11):975-982. View abstract.

Whigham, L. D., Cook, E. B., Stahl, J. L., Saban, R., Bjorling, D. E., Pariza, M. W., and Cook, M. E. CLA reduces antigen-induced histamine and PGE(2) release from sensitized guinea pig tracheae. Am J Physiol Regul.Integr.Comp Physiol 2001;280(3):R908-R912. View abstract.

Whigham, L. D., O'Shea, M., Mohede, I. C., Walaski, H. P., and Atkinson, R. L. Safety profile of conjugated linoleic acid in a 12-month trial in obese humans. Food Chem Toxicol. 2004;42(10):1701-1709. View abstract.

Whigham, L. D., Watras, A. C., and Schoeller, D. A. Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. Am.J Clin.Nutr 2007;85(5):1203-1211. View abstract.

White, H. M., Richert, B. T., Radcliffe, J. S., Schinckel, A. P., Burgess, J. R., Koser, S. L., Donkin, S. S., and Latour, M. A. Feeding conjugated linoleic acid partially recovers carcass quality in pigs fed dried corn distillers grains with solubles. J Anim Sci 2009;87(1):157-166. View abstract.

Won, J., Oh, M. H., Oh, J. M., Kang, M. S., Choy, J. H., and Oh, S. Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. J Food Sci 2008;73(8):N39-N43. View abstract.

Wu, Z., Li, D., and Gou, K. Overexpression of stearoyl-CoA desaturase-1 results in an increase of conjugated linoleic acid (CLA) and n-7 fatty acids in 293 cells. Biochem.Biophys.Res Commun. 7-30-2010;398(3):473-476. View abstract.

Xiao, Y. F., Wright, S. N., Wang, G. K., Morgan, J. P., and Leaf, A. Coexpression with beta(1)-subunit modifies the kinetics and fatty acid block of hH1(alpha) Na(+) channels. Am J Physiol Heart Circ.Physiol 2000;279(1):H35-H46. View abstract.

Xiao, Y. F., Wright, S. N., Wang, G. K., Morgan, J. P., and Leaf, A. Fatty acids suppress voltage-gated Na+ currents in HEK293t cells transfected with the alpha-subunit of the human cardiac Na+ channel. Proc.Natl.Acad.Sci U.S.A 3-3-1998;95(5):2680-2685. View abstract.

徐,c . X。哦,y,李,h·G。金,t·G。李Z. H., Yin, J. L., Jin, Y. C., Jin, H., Kim, Y. J., Kim, K. H., Yeo, J. M., and Choi, Y. J. Effect of feeding high-temperature, microtime-treated diets with different lipid sources on conjugated linoleic acid formation in finishing Hanwoo steers. J Anim Sci 2008;86(11):3033-3044. View abstract.

Xu, H., Lee, H. Y., Hwang, B., Nam, J. H., Kang, H. Y., and Ahn, J. Kinetics of microbial hydrogenation of free linoleic acid to conjugated linoleic acids. J Appl.Microbiol. 2008;105(6):2239-2247. View abstract.

Xu, X., Storkson, J., Kim, S., Sugimoto, K., Park, Y., and Pariza, M. W. Short-term intake of conjugated linoleic acid inhibits lipoprotein lipase and glucose metabolism but does not enhance lipolysis in mouse adipose tissue. J Nutr 2003;133(3):663-667. View abstract.

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Yamasaki, M., Kishihara, K., Mansho, K., Ogino, Y., Kasai, M., Sugano, M., Tachibana, H., and Yamada, K. Dietary conjugated linoleic acid increases immunoglobulin productivity of Sprague-Dawley rat spleen lymphocytes. Biosci.Biotechnol.Biochem. 2000;64(10):2159-2164. View abstract.

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Zhang, G., Shirai, N., Higuchi, T., Suzuki, H., and Shimizu, E. A comparative study of the effects of erabu sea snake (Laticauda semifasciata) lipids, green tea extract and conjugated linoleic acid on the swimming endurance of mice. Int J Vitam.Nutr Res 2009;79(5-6):362-374. View abstract.

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Zhao, W. S., Zhai, J. J., Wang, Y. H., Xie, P. S., Yin, X. J., Li, L. X., and Cheng, K. L. Conjugated linoleic acid supplementation enhances antihypertensive effect of ramipril in Chinese patients with obesity-related hypertension. Am.J Hypertens. 2009;22(6):680-686. View abstract.

Zhao, Z. Y., Wu, T. X., Tang, H. G., and Zhang, J. Z. Influence of dietary conjugated linoleic acid on growth, fatty acid composition and hepatic lipogenesis in large yellow croaker (Pseudosciaena crocea R.). J Zhejiang.Univ Sci B 2008;9(9):691-700. View abstract.

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Zhou, X. R., Sun, C. H., Liu, J. R., and Zhao, D. Dietary conjugated linoleic acid increases PPAR gamma gene expression in adipose tissue of obese rat, and improves insulin resistance. Growth Horm.IGF.Res 2008;18(5):361-368. View abstract.

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