Cardizem vs. Cordarone

• Are Cardizem and Cordarone the Same Thing?
• What Are Possible Side Effects of Cardizem?
• What Are Possible Side Effects of Cordarone?
• Cardizem是什么?
• What Is Cordarone?
• What Drugs Interact with Cardizem?
• What Drugs Interact with Cordarone?
• How Should Cardizem Be Taken?
• How Should Cordarone Be Taken?

Cardizem(diltiazem hydrochloride) andCordarone(amiodarone) are used to treat different types ofheartproblems.

Cardizem is used to preventchest pain(心绞痛). Cardizem may help to increase your ability to exercise and decrease how often you may get angina attacks.

Cordarone is used for many serious arrhythmias of the heart includingventricular fibrillation,ventricular tachycardia,atrial fibrillation, andatrial flutter.

Cardizem and Cordarone belong to different drug classes. Cardizem is acalcium channel blockerand Cordarone is an antiarrhythmic.

Commonside effectsof Cardizem include:

• dizziness,
• lightheadedness,
• weakness,
• tiredfeeling,
• nausea,
• upsetstomach,
• flushing (warmth, redness, or tingly feeling),
• sore throat,
• cough,
• stuffy nose, and
• headache.

Tell yourdoctorif you have unlikely but serious side effects of Cardizem including:

• fainting,
• slow/irregular/pounding/fast heartbeat,
• swelling of ankles orfeet,
• shortness of breath,
• unusualtiredness,
• unexplained or sudden weight gain,
• mental/mood changes (such asdepression, agitation), or
• unusualdreams.

Common side effects of Cordarone include:

• Nausea
• Vomiting
• Constipation
• Weight loss
• Fatigue
• Pulmonary fibrosis
• Heart block
• Heart failure
• Dizziness
• Tiredness
• Shaking ortremor
• Numbness and tingling
• Stomachpain
• Loss of appetite
• Sleepproblems (insomnia)
• Weakness
• Lack of coordination
• Warmth, tingling, or redness under yourskin

Tell your doctor if you have serious side effects of Cordarone including:

• easy bruising or bleeding,
• loss of coordination,
• tingling or numbness of the hands or feet,
• uncontrolled movements, or
• new or worsening symptoms of heart failure (such asankleorlegswelling, increased tiredness, increased shortness of breath when lying down).

Cardizem (diltiazem hydrochloride) is acalciumchannel blocker used to preventchestpain (angina). Cardizem may help to increase your ability to exercise and decrease how often you may get angina attacks.

Cordarone (amiodarone) is an antiarrhythmic drug used for many serious arrhythmias of the heart includingventricularfibrillation, ventriculartachycardia,atrialfibrillation, and atrialflutter.

Cardizem may interact with amiodarone,digoxin, atazanavir,cimetidine, quinidine, St. John's wort, azole antifungals,macrolideantibiotics, rifamycins, buspirone,cyclosporine,sirolimus,statins, anti-seizuredrugs,benzodiazepines,caffeine,pseudoephedrine,phenylephrine, or other drugs that can raiseheart rate. Tell your doctor all medications and supplements you use.

Cordarone may interact with beta-blockers and certaincalcium channel blockersresultinginan excessively slow heart rate or a block in the conduction of the electrical impulse through the heart. Cordarone increases thebloodlevels of digoxin,氟卡尼,phenytoin, and procainamide. Cordarone interacts withwarfarinand increases the risk of bleeding. Amiodarone can interact withsimvastatin,atorvastatin, andlovastatin, increasing the risk of severemusclebreakdown andkidneyfailure orliver disease. Cordarone is harmful to thefetusand to infants. It should not be administered duringpregnancyand women should not breastfeed while taking Cordarone.

Dosage of Cardizem is individually adjusted. Starting with 30mgfour times daily, before meals and at bedtime, dosage is increased gradually (given in divided doses three or four times daily) at 1- to 2-day intervals until optimum response is obtained. The average optimum dosagerangeis 180 to 360 mg/day.

Dosing varies depending onindication.