Buprenex vs. Oxycodone

Are Buprenex and Oxycodone the Same Thing?

Buprenex(buprenorphinehydrochloride) andoxycodoneare narcotics indicated for the relief of moderate to severepain.

Brand names for oxycodone includeOxycontin,Roxicodone, andXtampza ER.

What Are Possible Side Effects of Buprenex?

Commonside effectsof Buprenex include:

Tell yourdoctorif you have serious side effects of Buprenex including:

  • weak or shallow breathing,
  • lightheadedness,
  • fainting,
  • bluelipsor fingernails,
  • confusion,
  • feelings of extreme happiness,
  • fast or slowheart rate, or
  • urinating less than usual or not at all.

What Are Possible Side Effects of Oxycodone?

Common side effects of Oxycodone include:

  • constipation,
  • nausea,
  • stomachpain,
  • loss of appetite,
  • vomiting,
  • sleepiness,
  • tiredness,
  • drowsiness,
  • dizziness,
  • lightheadedness,
  • weakness,
  • itching,
  • headache,
  • dry mouth,
  • sweating, and
  • decreasesinthe ability to feel pain.

Tell your doctor if you experience serious side effects of Oxycodone including

What Is Buprenex?

Buprenex (buprenorphine hydrochloride) injectable is anarcoticdrug indicated for the relief of moderate to severe pain.

What Is Oxycodone?

Oxycontin (oxycodone hydrochloride) is anopioiddrug used for the management of moderate to severe pain, usually for an extended time period. Oxycontin is not an "as needed for pain (PRN) drug." Oxycontin is available as ageneric drug.

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What Drugs Interact With Buprenex?

Buprenex may interact withalcohol, other narcotic pain medications, sedatives, tranquilizers, sleeping pills,musclerelaxers, other medicines that can make you sleepy or slow your breathing,dexamethasone, imatinib,isoniazid, nefazodone, St. John's wort, antibiotics,antifungalmedications,barbiturates,bloodthinners,heartor blood pressure medications,HIV/AIDSmedicines, MAO inhibitors, medicines to treatnarcolepsy, phenothiazines, orseizuremedications. Tell your doctor all medications and supplements you use.

What Drugs Interact With Oxycodone?

Oxycodone may interact with alcohol, other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, monoamine oxidase inhibitors (MAOIs),antidepressants, methscopolamine,scopolamine,bladderorurinarymedications, or irritablebowelmedications.

Oxycodone may also interact with mixedagonist/antagonistanalgesics,macrolideantibiotics, azole-antifungals,proteaseinhibitors,rifampin, andcardiovasculardrugs (includingamiodaroneand quinidine).

How Should Buprenex Be Taken?

The usual dosage for persons 13 years of age and over is 1 ml Buprenex given bydeepintramuscularor slow (over at least 2 minutes)intravenousinjection at up to 6-hour intervals, as needed.

How Should Oxycodone Be Taken?

Oxycodone hydrochloride is available as controlled-release tablets in strengths of 10, 15, 20, 30, 40, 60, 80, and 160mgtablets (60 mg and above used only for opioid tolerant patients). The tablets must be swallowed whole because broken or chewed tablets release the drug too rapidly and because Oxycodone is rapidly adsorbed, too concentrated levels will be present in the body which can lead to death. Oxycodone may interact with other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, pentazocine, nalbuphine, butorphanol, or buprenorphine. Tell your doctor all medications and supplements you use. This opioid is often the drug of choice for addictive use and can easily lead to dependency. Some patients may developtolerancefor Oxycodone and need to be slowly weaned off the drug. Safety has not been established in children under age 18; caution or avoidance is suggested inpregnantandbreastfeedingwomen as infants can be born with opioid tolerance and depressed respirations. In addition, low concentrations of Oxycodone have been found inbreast milk.

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References

DailyMed. Buprenex Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b086772e-d15a-4d13-b1a2-38bfbde1f18c
FDA. Oxycontin Product Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020553s060lbl.pdf

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