Brilinta vs. Coumadin

Brilinta(ticagrelor) andCoumadin(warfarin) areblood-thinners used to reducecardiovasculardeathandheart attackinpatients withacute coronary syndromes(ACS).

Side effects of Brilinta and Coumadin that are similar include bruising, bleeding more easily, andnausea.

Side effects of Brilinta that are different from Coumadin include nosebleeds,headache,dizziness,cough,diarrhea, irregular heartbeat,high blood pressure,back pain,low blood pressure,fatigue, andchest pain.

Side effects of Coumadin that are different from Brilinta include vomitingstomachpain, bloating, gas, and alteredsenseof味道.

Both Brilinta and Coumadin may interact with other medications to preventblood clots,seizuremedicines,antifungalmedicines, andtuberculosismedicines.

Brilinta may also interact withantiviralmedicines to treatHIVorAIDS,cholesterolmedications,heartorblood pressuremedications, andopioidmedications.

Coumadin may also interact with antibiotics, sulfa drugs,antidepressants,herbal(botanical) products (includingcoenzyme Q10,cranberry,echinacea,garlic,ginkgo biloba,ginseng,goldenseal, or St. John's wort), secobarbital, andbarbiturates.

Common side effects of Brilinta are related to bleeding and include increased bleeding, nosebleeds, and bruising.

Other side effects of Brilinta include:

• dizziness,
• 咳嗽,
• nausea,
• diarrhea,
• irregular heartbeat,
• high or low blood pressure,
• back pain,
• fatigue, and
• chestpain

Common side effects of Coumadin include:

• easy bruising and bleeding,
• nausea, vomiting,
• stomach pain,
• bloating,
• gas, or
• altered sense of taste

Brilinta is aprescriptionmedicine used to treat people who have had a heart attack or severe chest pain that happened because their heart was not getting enoughoxygen.

Brilinta is used to lower your chance of having a heart attack or dying from a heart attack orstrokebut Brilinta (and similar drugs) can cause bleeding that can be serious and sometimes lead to death.

Coumadin is prescription medicine used to treat blood clots and to lower the chance of blood clots forming in your body. Blood clots can cause a stroke, heart attack, or other serious conditions if they form in the legs orlungs.

It is not known if Coumadin is safe and effective in children.

Brilinta may interact with other blood thinners, HIV or AIDS medications,seizure medications, and antifungals. Brilinta may also interact withdexamethasone,digoxin, nefazodone, antibiotics, cholesterol-lowering medications, and heart or blood pressure medications.

Brilinta may also interact with dexamethasone (Decadron), digoxin (Lanoxin,Digitek,Digibind), nefazodone (Serzone), certain antibiotics, cholesterol-lowering medications (statins), and heart or blood pressure medications.

Coumadin may interact with antibiotics, St. John's wort,aspirinor other nonsteroidalanti-inflammatory drugs (NSAIDs), and antifungal medications.

Coumadin may also interact with other medications to prevent blood clots, sulfa drugs, medicines to treat tuberculosis, antidepressants, herbal (botanical) products (includingcoenzymeQ10, cranberry, echinacea, garlic, ginkgo biloba, ginseng, or goldenseal), secobarbital, barbiturates, and seizure medications.

Brilinta can be taken with or withoutfood.

Brilinta is taken with aspirin. Talk to yourdoctorabout the dose of aspirin that you should take with Brilinta. You should not take a dose of aspirin higher than 100mgdaily because it canaffecthow well Brilinta works. Do not take doses of aspirin higher than what your doctor tells you to take. Tell your doctor if you take other medicines that contain aspirin, and do not take newover-the-countermedicines with aspirin in them.

• Take Coumadin exactly as prescribed. Your healthcare provider will adjust your dose from time to time depending on your response to Coumadin.
• You must have regular blood tests and visits with your healthcare provider to monitor yourcondition.
• If you miss a dose of Coumadin, call your healthcare provider. Take the dose as soon as possible on the same day. Do not take a double dose of Coumadin the next day to make up for a missed dose.
  • Call your healthcare provider right away if you:
  • take too much Coumadin
  • are sick with diarrhea, aninfection, or have afever
  • fall orinjureyourself, especially if you hit your head. Your healthcare provider may need to check you