Bonsity vs. Evenity

Are Bonsity and Evenity the Same Thing?

Bonsity(teriparatide injection) andEvenity(romosozumab-aqqg) are used to treatpostmenopausalwomen withosteoporosisat high risk forfracture.

Bonsity is also used to increasebonemassinmen withprimaryor hypogonadal osteoporosis at high risk for fracture; and for treatment of men and women with osteoporosis associated with sustainedsystemicglucocorticoidtherapyat high risk for fracture.

Evenity is also used in patients who have failed or are intolerant to other available osteoporosis therapy.

Bonsity and Evenity belong to different drug classes. Bonsity is aparathyroid hormoneanalog(PTH 134) and Evenity is a sclerostin inhibitor.

Side effectsof Bonsity and Evenity that are similar includejointpain, andheadache.

Side effects of Bonsity that are different from Evenity include body pain,nausea,流鼻涕,dizziness,diarrhea,constipation, indigestion,cough, andsore throat.

Side effects of Evenity that are different from Bonsity includemusclespasms, swelling of extremities, weakness,neck pain,insomnia, and numbness and tinglingsensation.

Bonsity may interact withdigoxin.

Evenity may interact with other drugs.

What Are Possible Side Effects of Bonsity?

Common side effects of Bonsity include:

  • joint pain,
  • body pain,
  • nausea,
  • runnynose,
  • dizziness,
  • headache,
  • diarrhea,
  • constipation,
  • indigestion,
  • cough, and
  • sorethroat

What Are Possible Side Effects of Evenity?

Common side effects of Evenity include:

  • joint pain,
  • headache,
  • muscle spasms,
  • 四肢肿胀,
  • weakness,
  • neckpain,
  • insomnia,
  • numbness and
  • tingling sensation

What Is Bonsity?

Bonsity (teriparatide injection) is a parathyroidhormone模拟(甲状旁腺素1 - 34)治疗后表示menopausal women with osteoporosis at high risk for fracture; to increase bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture; and for treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture.

What Is Evenity?

Evenity (romosozumab-aqqg) is a sclerostin inhibitor indicated for the treatment of osteoporosis in postmenopausal women at high risk for fracture, defined as a history of osteoporotic fracture, or multiple risk factors for fracture; or patients who have failed or are intolerant to other available osteoporosis therapy.

What Drugs Interact With Bonsity?

Bonsity may interact with digoxin. Tell yourdoctorall medications and supplements you use. Bonsity is not recommended for use duringpregnancy; it is unknown how it wouldaffectafetus. It is unknown if Bonsity passes intobreast milk. Because of a possible potential forosteosarcoma,breastfeedingis not recommended during treatment with Bonsity.

What Drugs Interact With Evenity?

Evenity may interact with other drugs. Tell your doctor all medications and supplements you use. Evenity is not recommended for use in women of reproductive potential so it is not intended for use by women who arepregnantor breastfeeding.

How Should Bonsity Be Taken?

The recommended dose of Bonsity is 20 mcg subcutaneously once a day. Bonsity may interact with digoxin.

How Should Evenity Be Taken?

A healthcare provider can administer 210mgEvenity subcutaneously once every month for 12 doses in theabdomen,thigh, or upperarm. Two separatesubcutaneousinjections are needed to administer the total dose of 210 mg Evenity.

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References
FDA. Bonsity Drug Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211939s000lbl.pdf

Amgen. Evenity Product Information.

https://www.evenity.com

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