Boniva vs. Prolia

Are Boniva and Prolia the Same Thing?

Prolia(denosumab) andBoniva(ibandronate) are used to prevent and treat bone loss (osteoporosis) in women who are at high risk for bonefractureaftermenopause.

Prolia and Boniva belong to different drug classes. Prolia is amonoclonal antibodyand Boniva is a二磷酸盐.

What Are Possible Side Effects of Boniva?

Common side effects of Boniva include:

What Are Possible Side Effects of Prolia?

Common side effects of Prolia include:

  • low calcium levels (especially if you have kidney problems),
  • weakness,
  • 便秘,
  • back pain,
  • muscle pain,
  • pain in your arms and legs,
  • anemia,
  • diarrhea, or
  • skin problems (eczema, blisters, dry skin, peeling, redness, itching, smallbumps).

You may also be more likely to get a serious infection, such as a skin, ear, stomach/gut, orbladderinfection while taking Prolia. Tell your doctor if you develop signs of infection, such as:

  • fever/chills,night sweats,
  • red/swollen/tender/warm skin (with or withoutpus),
  • severe stomach or abdominal pain,
  • ear pain or drainage, trouble hearing,
  • frequent/painful/burning urination, or
  • pink/bloody urine.
  • severe itching, burning, rask, blistering, peeling, or dryness of the skin,
  • 咳嗽,
  • shortness of breath,
  • pinpoint purple or red spots under your skin,
  • flu symptoms, or
  • weight loss.
Tell your doctor if your experience serious side effects of Prolia including jaw pain, new or unusual thigh/hip/groinpain, or bone/joint/muscle pain.

What Is Boniva?

Boniva (ibandronate) is a bisphosphonate drug that alters the cycle of bone formation and breakdown in the body used to treat or prevent osteoporosis in women after menopause. Boniva slows bone loss while increasing bone mass, which may prevent bone fractures.

What Is Prolia?

Prolia (denosumab) is amonoclonalantibody used to treat bone loss (osteoporosis) in women who are at high risk for bone fracture after menopause.

What Drugs Interact With Boniva?

Boniva may interact withaspirinor otherNSAIDs(non-steroidal anti-inflammatory drugs).

Boniva may also interact with products containing calcium, aluminum, magnesium, or iron (such asantacids, supplements or vitamins).

What Drugs Interact With Prolia?

Prolia may interact with steroids or cancer medicine,cyclosporine, sirolimus, tacrolimus, basiliximab, muromonab-CD3,mycophenolatemofetil,azathioprine,leflunomide, or etanercept.

How Should Boniva Be Taken?

Boniva取决于t的剂量he condition being treated.

How Should Prolia Be Taken?

The dose of Boniva is one 150 mg tablet taken once monthly on the same date each month.

Disclaimer

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References
SOURCE:

Genentech. Boniva Product Information.

https://www.gene.com/download/pdf/boniva_tablets_prescribing.pdf

Amgen. Prolia Product Information.

https://www.prolia.com

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