How Do Betablockers with Alpha Activity Work?

Beta-blockers with alpha activity are drugs used for lowering blood pressure.

Alpha- and beta-adrenergic receptors are types of adrenergic receptors that play a central role in thesympathetic nervous system. The sympathetic nervous system is the part of the nervous system that increases heart rate, blood pressure, breathing rate, and eyepupilsize. Stimulation of alpha and beta receptors can lead to constriction of blood vessels, resulting in increased blood pressure. Beta-blockers with alpha activity bind to alpha-1 and beta receptors and prevent their stimulation, leading todilationof the blood vessels.

Beta-blockers with alpha activity are indicated forhypertensionandhypertensiveemergency.

Beta-blockers with alpha activity can cause the following side effects:

• Dizziness
• 头晕
• Nausea
• Tingling sensation of scalp
• Fatigue
• Shortness of breath
• Swelling
• Itching
• Rash
• Alteredsenseof taste
• Irregular heart rate
• Hair fall
• Depression
• Low blood pressure
• Weight gain
• Diarrhea
• Headache
• Cough
• Sleepiness
• Impotence

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

Genericand brand names of beta-blockers with alpha activity include:

• Carvedilol
• Coreg
• Coreg CR
• Labetalol
• Trandate