螺内酯和青春痘特效药

Are Aldactone and Accutane the Same Thing?

Aldactone(spironolactone) andAccutane(isotretinoin用于治疗痤疮。

Aldactone is used off-label for acne. Aldactone is typically used to reduce fluid retention (edema) caused by heart, liver or kidney problems,high blood pressure(hypertension), and certain patients withhyperaldosteronism.

The brand name Accutane is discontinued in the U.S., butgenericversions are available.

Aldactone is an一个ldosteronereceptor一个ntagonist一个nd Accutane is aretinoid.

What Are Possible Side Effects of Aldactone?

Common side effects of Aldactone include:

  • skin rash,
  • headache,
  • dizziness,
  • nausea,
  • vomiting,
  • gas, and
  • stomach pain.

Tell your doctor if you have serious side effects of Aldactone including irregular heart rate, muscle pain or weakness, urinating less than usual, shallow breathing, tremors, confusion, or a severe skin reaction,hyperkalemia(high levels ofpotassiumin the blood), and numbness.

What Are Possible Side Effects of Accutane?

Common side effects of Accutane include:

  • dry skin,
  • itching,
  • rash,
  • dry nose,
  • nosebleeds,
  • cracks in the corners of the mouth,
  • dry mouth,
  • dry lips,
  • cracking or peeling skin,
  • inflammation of the whites of the eyes,
  • dry eyes,
  • joint pain,
  • back pain,
  • dizziness,
  • drowsiness,
  • nervousness, or
  • changes in your fingernails or toenails.

What Is Aldactone?

Aldactone (spironolactone) is an aldosterone receptor antagonist that causes the kidneys to remove water and sodium from the body, with reduced losses of potassium. Aldactone is used to reduce edema caused by heart, liver or kidney problems, high blood pressure (hypertension), and certain patients with hyperaldosteronism.

What Is Accutane?

Accutane (isotretinoin) is a retinoid used for the treatment and prevention of severe acne. The brand name Accutane is discontinued in the U.S., but generic formulations are available.

What Drugs Interact With Aldactone?

Aldactone may interact withlithiumor steroids.

Aldactone may also interact with other medicines that make you sleepy (such as cold or一个llergymedicine, sedatives,narcoticpain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety),digoxin,ACE inhibitors, or nonsteroidal anti-inflammatory drugs (NSAIDs).

What Drugs Interact With Accutane?

Accutane may interact with steroids,seizuremedications, ortetracycline一个ntibiotics

How Should Aldactone Be Taken?

Aldactone is available in 25, 50 and 100 mg tablets. Because of tumor formation in experimental animals, use in pregnancy should be avoided unless the benefits outweigh the potential risks to the fetus; women who are breastfeeding are advised not to use Aldactone. In addition, the drug should not be used to decrease the normal edema of pregnancy. An active metabolite of Aldactone appears in breast milk. Breastfeeding while using Aldactone is not recommended. If use of Aldactone is deemedessential, an alternative method of infant feeding should be used.

How Should Accutane Be Taken?

The recommended dose of Accutane is 0.5 to 2 mg per kg of body weight daily.

Disclaimer

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References

Pfizer. Aldactone Product Information.
https://www.pfizermedicalinformation.com/en-us/ald一个ctone
FDA. Accutane Product Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/018662s059lbl.pdf

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